E-Newsletter 3rd Edition

September 2011

A Message from ASHI's Secretary, Dorothy Levis

Fall is arriving and our annual meeting is just around the corner.  I look forward to seeing so many friends each year as well as attending the sessions. ASHI has been busy preparing for the International Summer School in addition to our annual meeting.  September is time for ABHI certification exams and I send best wishes to all who are taking their exams at this time. Fall also is the time for labs to plan for next year's proficiency testing and at the meeting we will hear about some exciting enhancements to the surveys.

Many ASHI members have responded to the call for volunteer opportunities and will soon be hearing about upcoming committee activities at the annual meeting. Watch for announcements for these committee meetings.  The pre-meeting accreditation inspector's workshop will train volunteers interested in doing inspections and will also help laboratories learn more about the inspection process.  Seasoned inspectors need to attend the afternoon session every two years or do on-line review sessions to stay current.  The Accreditation Update session always brings the newest information from the Accreditation Review Board (ARB), Quality Assurance and Standards (QAS), Proficiency Testing (PT) and Centers for Medicare and Medicaid (CMS). Attending this session helps prepare your laboratory for its next inspection.  Also, this year there will be a special workshop on CPT codes for Histocompatibility. 

We hope our members are enjoying this e-newsletter with its timely updates between the Quarterly issues.  Melissa Roberts is your contact for comments or suggestions for this information. She may be contacted via .

ASHI 37th Annual Meeting/ Registration

Early Registration Deadline: September 19  
(Register Now - Click Here)

The ASHI 37th Annual Meeting is only one month away.  If you haven't registered yet, there is still time to make the early registration deadline and save up to $135 on registration fees.

Be sure to take advantage of all that this year's meeting has to offer.  Beginning with new morning sessions aimed at providing attendees with an overview of the day's theme, and including a full day dedicated to both bone marrow and solid organ transplantation, this year's meeting has been designed with the attendees needs in mind.

Three Ways to Register

1. INTERNET

For online registration, click here.

2. FAX

Fax your completed registration form, including payment information to ASHI at: 877-716-6404
 
3. MAIL
Mail your completed registration form, including payment information to:

ASHI
15000 Commerce Parkway, Suite C
Mount Laurel, NJ 08054
All checks must be made payable to ASHI, in U.S. dollars and drawn on a U.S. bank

To register, download the Annual Meeting brochure or for more information, click here.

Get 'In the Groove' with Soul Incision at the House of Blues

Tickets are still on sale for ASHI's Annual Banquet at the House of Blues.

Eat, drink and get jazzed in true New Orleans style at this unique venue.  Located in the heart of the world famous French Quarter, the House of Blues is just a short walk from the Sheraton New Orleans. Tickets for this soulful event include an open bar and a hearty buffet of local favorites such as Catfish Bites, BBQ Brisket and Pistolettes. Cut a rug on the spacious dance floor as you listen to the ever popular stylings of Soul Incision. Don't miss the chance to enjoy classic southern hospitality with ASHI in this unique and down to earth atmosphere.

Top 3 Reasons to Stay at ASHI Annual Meeting Host Hotel
Reservation Deadline: September 14

ASHI Discounted Room Rate:  $239+tax (rate includes complimentary Internet)
Online Reservations: www.starwoodmeeting.com/Book/ashi1
Toll Free Reservations: (800) 325-3535

The Sheraton New Orleans is the official host hotel for the ASHI 37th Annual Meeting.  The reservation deadline is quickly approaching, so book now!

1.    Great Location
The Sheraton New Orleans is in the center of it all.  Visit Bourbon Street, ride the Canal Street Trolley or stop in Cafe Du Monde for a cafe au lait and beignet.  By staying at the Sheraton New Orleans, youíll be surrounded by all that New Orleans has to offer. 

2.    Great Convenience
Cut your travel time to just a minute by staying steps away from all meetings, receptions and events. Eliminate the stress commuting to the Annual Meeting when all you have to do is open your hotel room door and hop on the elevator.  Networking opportunities are everywhere when you stay at the host hotel.  Network in the lobby, in the elevator or even at the pool!

3.    Support ASHI
ASHI has worked diligently with the hotel to provide the best rate and service as a convenience for meeting attendees. In order to reserve the required meeting space, ASHI has a contractual obligation to fill a specified number of sleeping rooms.

If reservations are made at other hotels, ASHI will be at risk for defaulting on this obligation. Failure to meet the contractual obligation will result in ASHI paying higher costs (penalties) to the hotel. This will likely force ASHI to increase annual registration fees for future meetings.

For more information the Sheraton New Orleans, click here.

MEMBERSHIP COMMITTEE SPOTLIGHT

Over the last several years, the ASHI Membership Committee has been working to update the ASHI membership categories and benefits so that they will be most useful and cost-effective to those in our field.  The Technologist Membership category was added several years ago and now represents nearly 20% of our total membership.  More recently, the Affiliate Membership category was added to allow vendors and consultants to be an official part of our organization.  Some of the benefits of Affiliate Membership include access to ASHI-U and Human Immunology on-line as well as the ability to serve on ASHI committees.  We have also increased the benefits for Institutional Members. Institutional Members can now receive discounted registration for up to 6 individuals for the ASHI Regional and Annual meetings in addition to continuing education credits from 24 modules from ASHI-U, free of charge.  The Institutional Members are also eligible to receive free access to Human Immunology online or can opt for a paper copy of Human Immunology for only $30.  All ASHI members continue to receive the ASHI Quarterly, have free access to ASHI-U and receive discounted registration at ASHI Regional and Annual meetings.   It is our hope that these expanded categories and benefits will encourage membership for the continued growth of our organization.  For specific descriptions of all categories, please refer to the Membership page of the ASHI website at http://www.ashi-hla.org/about/membership/.


Current membership totals by category

ASHI's Recent Accomplishments in National Transplant and Laboratory Affairs

For many ASHI members, awareness of ASHI's activities is limited to attendance at annual and regional meetings, having and performing lab inspections, subscribing to the PT program, reading the Quarterly and Human Immunology, and completing continuing education from ASHI University. But there's a lot more going on behind the scenes. Most members don't realize that ASHI is heavily involved in influencing national policies on transplantation and advocating for histocompatibility laboratories and professionals.  Recently, ASHI has made huge strides in increasing our involvement with other organizations and government agencies. The following is a list of the many activities ASHI has been involved in during the past year (in no particular order):

• Entered into Cooperative Agreement with The Joint Commission (TJC) - the first organization to do so!

• Participated in The Joint Commission Liaison meeting as well as the Laboratory Professional and Technical Advisory Committee (Lab-PTAC), a group of laboratory professionals from many disciplines that reviews TJC activities as they relate to the operation and accreditation of the laboratories

• Responded to UNOS proposals including the new kidney allocation algorithm 

• Was invited to participate in the UNOS Society Leadership Roundtable to discuss issues of mutual interest

• Provided written testimony and an oral presentation to the Center for Medicare and Medicaid Services (CMS)/Medicare Evidence Development & Coverage Advisory Committee (MEDCAC) on the impact on kidney transplant graft survival of alternative modalities for treating anemia in individuals with chronic kidney diseases, i.e. red blood cell transfusions vs. erythropoiesis-stimulating agents (ESAs)

• Responded to the Technology Assessment Program at the Agency for Healthcare Research and Quality on the Impact of Pre-transplant Red Blood Cell Transfusions in Renal Allograft Rejection Commented on a Proposed Decision Memorandum issued by CMS as part of its ongoing National Coverage Analysis for ESAs in nephrology

• Attended an open meeting with a coalition of laboratory professional associations, including the American Clinical Laboratory Association (ACLA) and Association for Molecular Pathology (AMP), on the issue of Food and Drug Administration (FDA) oversight of laboratory developed tests (LDTs).

• Responded to FDA draft guidance on commercially distributed in vitro diagnostic products labeled for research use only, and investigational use only

• Initiated a letter writing campaign for ASHI members regarding FDA oversight of LDTs

• Was invited to be on the steering committee for The Office of Blood Research and Review (OBRR) Heritable Marker Workshop to clarify and provide updated regulatory and scientific information to manufacturers of CBER-regulated heritable markers in vitro diagnostic kits

• Endorsed the American Society for Transplantation (AST) document addressing the FDA's changes to the Laboratory Developed Assays rules - this document was presented on Capitol Hill and to the FDA and Department of Health and Human Services (DHHS)

• Was invited to participate as a key partner in a consensus conference on paired and chain kidney exchange by the AST Kidney Pancreas Advisory Council

• Was invited to participate in the formation of the AST Transplant Diagnostics Community of Practice

• Held a Transplant Histocompatibility Conference to address concerns regarding the use of solid-phase HLA antibody test results for assessing risk in organ transplants.

• Participated in the AMA Molecular Pathology Coding Workgroup and attended a CMS meeting on CPT codes for molecular diagnostic tests. Made recommendations on National Correct Coding Initiative (NCCI) edits and Medically Unbelievable Edits (MUE) for HLA codes.

• Participated in a coalition with the AMP and the American College of Medical Genetics (ACMG) to pursue PhD status as a Qualified Healthcare Practitioner for Molecular Genetic studies in Genetics and Oncology

• Collaborated with the AABB in a response to the DHHS's Request for Information regarding the development of a public-private partnership to establish a national biovigilance system to prevent malignancies and infections from being transferred by blood, organ and tissue donors

• Participated with ASBMT and NMDP on the Harmonization of Histocompatibility Typing Terms Group

• Commented on proposed changes to NMDP standards

• Was invited to join the Worldwide Network for Blood Marrow Transplantation (WBMT) and participate in planning a scientific symposium at the BMT Tandem meetings and EBMT in 2012.

• Was invited by the Foundation for the Accreditation of Cellular Therapy (FACT) and the Joint Accreditation Committee of ISCT-EBMT (JACIE) to review and comment on the FACT-JACIE International Standards for Cellular Therapy Product Collection, Processing, and Administration

• Was invited to join the Coordinating Council on the Clinical Laboratory Workforce (CCCLW) to promote clinical laboratory education to ensure a qualified workforce for the future

• Partnered with the European Federation for Immunogenetics (EFI) and the Asia-Pacific Histocompatibility and Immunogenetics Association (APHIA) to organize the 8th annual International Summer School for Immunogenetics

• Partnered with the Association of Medical Laboratory Immunologists (AMLI) and the AST Basic Science Advisory Council to host two satellite symposia at the 2011 FOCIS annual meeting

• Collaborated with FOCIS on a call for clinical trial contributions for their Translational Immunology Update ePublication

• Was invited to participate in program planning for the FOCIS 2012 meeting

• Was invited to join the National Medical Laboratory Professionals Week coalition as a supporting organization

• Was invited to have an entry in a directory of CMS-deemed health care accrediting organizations.

ASHI would like to thank the many volunteers who have spent countless hours representing ASHI at meetings and writing comments and testimonials on our behalf. Without them, we could not accomplish our vision of being the foremost authority and leading educational resource in immunogenetics and histocompatibility and to improve the quality of human life and health through the translation and implementation of scientific innovations to clinical practice. The many invitations we have received to participate in coalitions, workgroups and program planning committees speak to our increased visibility in the national and international transplantation arena.

ASHI-U and Lab Manual Update

The Education Committee would like to provide an update to membership regarding the status of ASHI University. The initial model for ASHI-U successfully provided a platform for technologists to engage in educational modules while earning necessary continuing education credits. Initially, our next steps were to build more modules until we covered all techniques and methodologies employed in the histocompatibility lab.

Coinciding with the development of ASHI-U was the growing need to update the ASHI Lab Manual. Members of the committee asked to address the needs of revising the Lab Manual and those from ASHI-U conceived a product which is complimentary to each (ASHI-U and the Lab Manual) while maintaining their own distinct value to membership. The end product will be a combined web-based educational resource and lab manual available to all members as a benefit to membership.

The ASHI Board of Directors has charged the Education Committee with developing this new model. Development of new modules has stopped and we have begun revising current ASHI-U modules to provide a distinct lab manual section which will eventually be a stand alone product as well as have a link to the corresponding ASHI-U module.

This new product will be a member benefit and we need members to assist us in completing these modules to meet our very aggressive timeline for completion. If you have previously authored a section of the Lab Manual or ASHI-U, we need your help. You have already done much of the work and some simple changes in format will allow you to be recognized as a published author.

If you previously missed out on the opportunity to author an ASHI-U module or section of the Lab Manual and have an interest in being an author, or have an interest in reviewing modules for scientific content, please contact us via the ASHI-U website or by contacting Melissa Roberts at Association Headquarters, .

Dean Sylvaria & Lori Osowski
Co-chairs, Education Committee

This E-Newsletter is sponsored by:

Life Tech Submits 3500 CE Analyzer and HLA Typing Kits for FDA 510(k) Clearance

Life Technologies announced on August 1st, 2011, in a press release, that the company had completed its clinical trial and had subsequently submitted the 3500 Dx Genetic Analyzer capillary electrophoresis sequencer and Secore® HLA typing kits for US Food and Drug Administration 510(k) clearance.  If cleared, the assay would be the first sequencing-based HLA typing test to receive clearance from the FDA.  To read the press release click here:
http://www3.appliedbiosystems.com/cms/groups/mcb_marketing/documents/generaldocuments/cms_097440.pdf

In response to the July, 2011 IMGT database update of over 400 allele discoveries, updates have already been made to the Secore® product line and uTYPE® analysis software.  Product line updates include the addition of 3 new GSSP kits for additional ambiguity resolution, and references of the July, 2011 IMGT release have been built-into the analysis software for the most up-to-date data analysis.  Continual maintenance of kits and software is the key to being able to deliver 100% resolution, 100% of the time.

Life Technologies is planning to exhibit at the annual ASHI meeting this October, highlighting the Secore® SBT workflow.  The company will also host a luncheon at the conference, including speakers from one of the US clinical trial sites and a leading registry.

American Society for Histocompatibility and Immunogenetics

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Home > Travel Expenses

Travel Expenses

The following are approved forms and documentation for use when planning and submitting reimbursement request for ASHI related travel. We advise bookmarking this page for quick access and most up-to-date documentation.

Best Practices Travel Guidelines

Financial Policy - Board Approved 

Reimbursement Request Form

 

 

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Home > E-Newsletter 2nd Edition

E-Newsletter 2nd Edition

June 2011

A Message From The Vice President Of Operations, John Hart

Just as each spring brings a renewal of nature, there are many new, exciting things happening at ASHI.  The current newsletter highlights many of the areas that continue to grow and be updated, affecting both our membership and those who interact with us through the delivery of laboratory services. 

If you are planning to attend the International Summer School, you won’t want to miss the opportunity to apply for a travel stipend.  The Proficiency Testing committee continues to improve our first class program and the Molecular Pathology Workgroup is busy with the overhaul of the Histocompatibility CPT codes.  Opportunities for ASHI members also exist with FOCIS and the IDAWG 16th International Histocompatibility Workshop survey.

All of these activities highlight the volunteer efforts of so many ASHI members.  Getting involved is one of the many ways members can contribute to our field.  If you have any comments or suggestions for future e-newsletters, please, send them to Melissa Roberts via email, .

Please enjoy this issue.

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In the Groove

Many thanks to Michael Gautreaux for participating in our online social media discussion and suggesting "In the Groove"  as the new official name of the ASHI E-Newsletter.  To get connected with other ASHI members and participate in industry-related discussions, visit http://www.ashi-hla.org/news/connect/ to get started.  Then post YOUR first discussion!

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2011 International Summer School
San Juan, Puerto Rico

ASHI announces that two travel stipends will be available to support students/scientists who wish to attend the 2011 International Summer School to be held at the Sheraton Old San Juan in Puerto Rico from September 19-22, 2011.  

An announcement regarding the details of the International Summer School and the opening of the travel stipend application process will be made soon.  In preparation for that announcement, the information below has been made available. 

Applicants for travel stipends must supply:

• Completed application
• Statement of motivation for attending this meeting
• A summary of current research
• Letter of support from their supervisor/head of department
• Curriculum Vitae

Travel stipend criteria are listed below:

• Have current ASHI membership
• The applicant must currently be enrolled or have recently completed an advanced degree (Ph.D., MD, or equivalent)
• Research and active technical staff will also be considered
• Have background slides and data (or research plan) for a 20 minute presentation to be given at the International Summer School
• Stay for the duration of the meeting

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Membership Directory

The 2011 Membership Directory is now available on the ASHI web site.  It is available in both a pdf version and an online search option.  To view the directory and verify that your contact information is correct, please log in to the Members Only section.  To correct or update your information, please click on “Update Your Profile” from the red navigation toolbar.  Be sure to click the "Submit" button upon completion. 

NOTES:

• The pdf version of the Membership Directory is published annually.  For the most up-to-date information, please use the online search option.
• The ASHI Accredited Laboratories is listed separately in the Lab Center section of the web site under Accreditation.

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Committee Spotlight: The ASHI Proficiency Testing (PT) Program

Those of you who aren’t directly involved in entering ASHI PT Survey results or, in  reading the Performance and Summary Reports may not be aware of the incredible number of improvements that have been made during the last 2 years as ASHI has changed to an entirely in-house system. 

The ASHI PT Program offers surveys designed to assess laboratory performance in HLA typing by serological, low resolution DNA, and/or high resolution DNA   methods: the detection of HLA B27 by any method; HLA antibody screening and/or specificity identification and crossmatching by different methods; and monitoring engraftment after allogeneic HPC transplant.   Some of the most significant improvements, thanks in large part to the efforts of our PT Program’s Data Manager, Danny Youngs, are the following:

• All results entry and Summary and Performance Reports for 2010 and 2011 use the new WHO HLA nomenclature.
• The entry of results is more user friendly– all results can be entered at once for each sample or partially entered and saved for additional entry later.  All results for the B27 and EMO Surveys can be entered on a single “page”.
• Analyses of consensus for antibody specificities for all “regions” are now combined.  (All regions receive the same sera for analysis but separate analyses in the past caused some discrepancies between regions in consensus results.)
• The selection of “serology equivalent” results for low resolution molecular no longer requires a separate field entry (e.g., B*(60)40 or B*(61)40 are now possible low resolution molecular entries).
• The collected information about cell quality for HLA Typing and Crossmatching are now included in the Summary Reports for Surveys HT and AC, respectively.
• Types reported for any loci are included in the combined analyte grades, even if only results for a single locus or single allele are reported (as might occur for labs only doing disease or drug hypersensitivity risk testing).
• The PT Vendor continues to provide samples for HLA Typing with substantial allele variety from ethnically diverse populations.  Three new HLA-alleles have been identified in the last two years: B*27:51, A*03:71 and another new A*03 allele. This new A*03 allele has an exon 4 substitution at nucleotide position 643 that changed codon 191 from histidine to aspartic acid.  In addition, one of the samples sent in 2010 surprised laboratories by having a DRB1*15 haplotype without a DRB5 gene and some alleles previously thought to be “rare” have been seen more than once (e.g., A*23:17).  The expert evaluation of results enhances the educational value of these surveys.
• Performance Reports and Summary Reports for each survey are available at the same time, allowing survey participants immediate access to explanatory comments about the unusual features of any of the samples tested. 
• Typing for Cells sent for crossmatching now includes DQA1 types in addition to A, B, C, DRB1, DRB3/4/5, DQB1, and DPB1 types.   This assists labs in interpreting the PT Crossmatch results in ways that are similar to the way they can interpret clinical crossmatch results.
• Laboratories accredited by ASHI are now able to request that their Survey Performance Reports be sent directly to the ASHI Accreditation Review Board.  (Laboratories accredited by the CAP continue to be able to request that their Performance Reports be sent to the CAP.)   This new option for ASHI accredited laboratories will reduce considerably the number of documents laboratories will need to submit with their ASHI re-accreditation applications.
• The deadlines for submission of results were extended to 11:59 PM Pacific Time on the Survey Due dates to accommodate west coast laboratories with last-minute entries.

There have been other improvements as well, many of which were made in response to user comments. The committee is happy to receive questions and suggestions from PT users.  For further questions about the ASHI PT Surveys or, to provide suggestions please contact Cecilia Blair ( or 856-642-4411).

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Major Changes To Molecular CPT Coding For 2012

As most of you are aware, the current CPT codes for molecular testing, including HLA, are composed of a complex list of "stacking" codes that must be used to build the charge for any non-microbiology molecular test.  This has proved to be cumbersome and confusing for those creating the charge and has not been informative for the payors who are billed for this charge, despite the use of modifiers to identify the gene tested.  

In December of 2009, the AMA CPT Editorial Panel convened a workgroup to propose solutions to issues for coding molecular assays in cancer, genetics and histocompatibility.   ASHI as part of the original workgroup has participated actively for the last year and a half in the development of new codes for these molecular assays.   In March of this year (in an unprecedented move) the AMA CPT Editorial Panel released a draft of the molecular testing codes that had been approved for 2012 and asked for public comment.   The link to this information was provided at that time in a blast email from ASHI Headquarters.    The link and a brief overview provided by the AMA is given below.  ASHI continues to participate in the workgroup as it responds to the public comment and works on other issues. 

For more information about the workgroup process and what it will mean for the coding of molecular testing, a link is provided to an article written by Mark Synovec, one of the co-chairs of the workgroup, and published in CAP Today. 
http://digital.olivesoftware.com/Olive/ODE/CapToday/Default.aspx?href=CAP/2011/04/01&pageno=5&view=document

Because of the extensive nature of the changes, there will be a workshop at the ASHI Annual Meeting that will provide information on how these codes should be used.  The presentation will be given by ASHI members who participated in the workgroup.  There will also be time for questions and answers at the end of the workshop.

FROM THE AMA
Following is a summary of the announcement that is located on the CPT web site at:
http://www.ama-assn.org/ama1/pub/upload/mm/362/request-for-molecular-pathology-code-review-and-feedback.pdf (ed.note:  this was included in the March 2011 blast email from ASHI)
 
In December 2009, the AMA CPT Editorial Panel convened a workgroup to propose solutions to issues for coding molecular assays in cancer, genetics and histocompatibility.

• The output of that workgroup, illustrated in the test descriptors provided and available in this release for review and comment to interested stakeholders before publication for CPT 2012, represents the major changes to molecular assay reporting that are coming next year.
• These changes do NOT affect molecular microbiology tests or most cytogenetic assays.
• The most commonly-performed tests (Tier 1) will have a test (analyte) specific CPT code.
• Less commonly-performed tests (Tier 2) have been assigned to 9 resource level codes determined by level of resources required for their performance and interpretation.
• Analytes/tests that have new codes assigned and are listed in Tiers 1 and 2 MUST be coded using the most specific CPT code available and NOT with 'stacking codes' (83890-83914).
• CPT 'stacking codes' (83890-83914) will remain available to report tests in 2012 for tests that have not been assigned analyte-specific or resource level codes. 'Stacking codes' will be retired at the conclusion of this initiative (most likely 2013).
• This process is ongoing and there will be significant additional analytes included in 2013

Access to the proposed descriptors is necessary to ensure that a broad base of review is performed by those who will be required to report these services.
Any requests for revision should be sent to AMA staff by April 15th at .

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Opportunity for International Collaboration and Visibility: Call for Clinical Trial Contributions

ASHI is a member of the Federation of Clinical Immunology Societies (FOCIS), which has created an opportunity for collaboration with their member societies in building an interdisciplinary clinical trial listing in the new ePublication, Translational Immunology Update. The section will include phase 1 and 2 studies using novel immunotherapeutics or standard immunotherapeutics in new diseases or new ways.  The trials will be formatted in a table with key variables including the drug name, disease, N, overall study design, primary outcome variable and result.  The goal is for readers to have a better understanding of the application of clinical immunology outside of their field. To participate, submit trials of which you are aware to http://translationalimmunology.pbworks.com/Clinical-Trial-Contributions. Please note, you will need to request access to the contribution site, which will be granted within 24 business hours. 2011 publication deadlines: June 1, August 1, October 1, December 1.

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ASHI At FOCIS 2011

The Federation of Clinical Immunology Societies (FOCIS) is the leading collaborative forum for education, research and networking across the broad field of clinical immunology. ASHI has partnered with the American Society for Transplantation (AST) and the Association of Medical Laboratory Immunologists (AMLI) to sponsor two exciting Member Society Symposia at FOCIS 2011 on Thursday, June 23, 2011 at the Marriott Wardman Park Hotel, Washington, D.C.  ABHI has approved the ASHI/AMLI symposium for three (3) hours or .45 CECs. Please join us as we explore the various immunologic issues that bind our community.

For more information on FOCIS 2011:
June 23, 2011 Washington D.C.
http://www.focisnet.org/FOCIS/index.php?option=com_content&task=view&id=120&Itemid=152

ASHI/AST co-sponsored symposium:
June 23, 2011 8:00 am-12:15 pm.
Tolerogenic B Cells and B cell Signatures in Transplant Rejection and Tolerance. 
http://www.focisnet.org/FOCIS/images/focis2011/ast-ashi agenda final-3.8.pdf
 
ASHI/AMLI co-sponsored symposium:
June 23, 2011 12:45 pm-4:15 pm.
Recent Progress in Elucidating the Role of Host Genetics and Immune Responses in Transplantation and Infectious Disease: Implications for the Clinical Immunology/HLA Laboratory. 
http://www.focisnet.org/FOCIS/images/focis2011/amli-ashi agenda-4.14.11.pdf
Note: This symposium has been approved for three (3) hours or .45 ABHI CECs.
 
Additional FOCIS Educational Offerings: 
http://www.focisnet.org/FOCIS/index.php?option=com_content&task=view&id=17&Itemid=30

To learn more about FOCIS and membership:
http://www.focisnet.org/FOCIS/index.php

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IDAWG Survey

ASHI IDAWG 16th IHIW Survey of Immunogenetic Data Management and Analysis Practices

ASHI is collaborating with the Immunogenomics Data Analysis Working Group (IDAWG) to survey the histocompatibility and immunogenetics community on current data management and analysis practices.

The IDAWG is an international collaboration of histocompatibility and immunogenetics investigators with the goal of making immunogenetic data more useful across studies and between research groups. Toward this end, the IDAWG has initiated an International Histocompatibility and Immunogenetics Workshop (IHIW) project for the development of new data-management tools and documentation standards.

This IHIW project will be informed by the responses to the ASHI IDAWG 16th IHIW Survey of Immunogenetic Data Management and Analysis Practices.  This is a broad survey of the approaches for HLA and KIR data management and transmission, HLA ambiguity management and resolution, and primary data analysis as currently applied by the community.

The survey is available at http://www.surveymonkey.com/s/IDAWG, and should take approximately 15 minutes to complete. All members of the histocompatibility and immunogenetics community are invited to take the survey.

The survey can be submitted anonymously, and although survey participants are invited to take part in the larger IDAWG Workshop project, information specific to individual laboratories will be kept confidential; individual laboratories will not be identified without providing consent.

When survey participants have indicated their interest, the survey will be followed-up with synthetic datasets for the purpose of demonstrating HLA ambiguity resolution and primary data-analysis practices.

More information about this project can be found at http://immunogenomics.org/workshop.html. Please direct any questions or comments about the survey to .

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This E-Newsletter is sponsored by:

 

 

 

Life Technologies Initiates Clinical Trials Leading to 510(k) Submission of a Class I and Class II HLA Sequence-Based Typing Solution

Life Technologies announced on March 21, 2011 in a company press release that the company is entering into clinical trials to prove the safety and effectiveness of their DNA sequence-based typing platform for analysis of the HLA system for the purpose of submission for 510(k) clearance. 

The company’s exhibit at the American Association for Clinical Chemistry (AACC) Annual Meeting in Atlanta, Georgia July 24-28th will include components of the HLA workflow that are planned for submission.  Featured products include the 3500 Dx Genetic Analyzer system, SeCore® kits and uTYPE® analysis software. Company representatives will be available at the exhibit to discuss the HLA workflow in detail.  To read the press release click here.

Other Life Technologies HLA events include a luncheon on June 17th during the ASHI Regional Meeting in Seattle.  The event will feature customer discussions about first-hand research experiences with the company’s HLA-related products including SeCore® SBT kits, uTYPE® Analysis Software, AllSet™ Gold SSP kits, and the PlexMark® BioMarker Panel.  Please contact Bill Yang () to attend.

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In the Groove

Welcome to 'In the Groove' an ASHI e-newsletter publication.  The e-newsletter contains timely and important information for professionals working in histocompatibility, immunogenetics and transplantation. This e-newsletter is intended to supplement the ASHI Quarterly by providing information that just can’t wait until the next issue.

The e-newsletters include updates from ASHI committees, proposals out for public comment from regulatory agencies, news from other associated societies, surveys, notices about ASHI meetings and other meetings of interest to our members, tables of contents from recent issues of Human Immunology, and news from our sponsoring vendors. The electronic format provides the opportunity to read information on the go from portable devices and the ability to click directly to the items that interest you most.

If you have any comments or suggestions for future e-newsletters, please send them to Melissa Roberts via email:

 

2012 Newsletters

2012 1st Edition (March 2012)

2011 Newsletters

2011 - 4th Edition (December 2011)
2011 - 3rd Edition (September 2011)
2011 - 2nd Edition (June 2011)
2011 - 1st Edition (March 2011)

American Society for Histocompatibility and Immunogenetics

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Home > E-Newsletter 1st Edition

E-Newsletter 1st Edition

March 2011

A Message from the President Elect, Amy Hahn

Welcome to the inaugural edition of the ASHI e-newsletter! We’re starting small, but future e-newsletters will be full of the timely and important information you need as a professional working in histocompatibility, immunogenetics and transplantation. This e-newsletter isn’t intended to take the place of the ASHI Quarterly, rather it will supplement it by bringing you information that just can’t wait until the next issue. The items you see in the e-newsletter will include news from ASHI committees, proposals out for public comment from regulatory agencies, news from other associated societies, surveys, notices about ASHI meetings and other meetings of interest to our members, tables of contents from recent issues of Human Immunology, and news from our sponsoring vendors. By having this information in electronic format, you’ll be able to click right through to the items that interest you most. We hope that you’ll find this e-newsletter to be a useful and educational benefit of being a member of ASHI. If you have any comments or suggestions for future e-newsletters, please send them to Melissa Roberts via email:

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Save the Date – ASHI Regional Workshops

The ASHI Education Committee cordially invites you to attend this year’s ASHI Regional Workshops in Chicago and Seattle. We are honored to have our President, Dr. Geoffrey Land, provide a Keynote Address on volunteerism at our Thursday evening reception. Make plans to arrive early   - you don’t want to miss out on this opportunity. The faculty is eager to share their expertise and experience with the attendees. Our goal is to provide an interactive, educational atmosphere that will provide ASHI members,  from the novice to experienced bench technologists and supervisors, with some necessary theory and practical application in the laboratory.  For more information or to download the regional brochure, click here.

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Changes to CPT Appendix I Effective January 1, 2011

We would like to bring to your attention a change that was made in the AMA 2011 CPT Coding Manual Appendix I.  (see page 431 of the 2011 Standard Edition of the CPT Coding Manual. )

The Histocompatibility/Blood Typing/Identity/Microsatellite section has been changed for 2011.  Modifiers are now available for all HLA loci.  
•  Modifier 4E, previously designated DR, has been changed to 'DRB All' and should only be used for a combined low resolution DRB1/3/4/5 typing.
•  Modifiers 4F and 4G, previously designated DQ and DP, have been changed so that they now code for DQB1 and DPB1 respectively. 
•  HLA D has been deleted. 
•  Unique modifiers for DRB1, DRB3, DRB4, DRB5, DQA1, and DPA1 have been added. 

Labs that are using the genetic testing code modifiers from Appendix I should make the appropriate changes to their CPT codes. 

From CPT codes, Appendix I, Genetic Testing Code Modifiers

4A HLA-A*
4B HLA-B*
4C HLA-C*
4E HLA DRB all (use for typing for DR that includes DRB1/3/4/5 in the same kit or same test.)
4P HLA-DRB1*
4Q HLA-DRB3*
4R HLA-DRB4*
4S HLA-DRB5*
4T HLA-DQA1*
4F HLA-DQB1*
4U HLA-DPA1*
4G HLA-DPB1*

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 AST Establishes Transplant Diagnostics Community of Practice

The American Society of Transplantation is excited to announce the launch of the Transplant Diagnostics Community of Practice (Tx Dx COP).  This community of practice is open to all transplant professionals involved in diagnostics, including transplant pathologists, immunogeneticists, and other laboratory medicine specialists.  The COP serves as a forum to network and share ideas, expertise, and knowledge to achieve shared goals.
 
An executive committee was formed to represent the diverse group of transplant diagnostics, and consists of a Chair, Co-Chair, and 3-4 Members-at-Large.  Overall goals of the Tx Dx COP are to:

•  provide a mechanism by which physicians and medical professionals involved in transplantation diagnostics can network

•  serve as an authoritative voice on matters related to diagnostics in transplantation for the AST, as well as other medical organizations and governmental institutions

•  create and promote the spread of best practices through the communication, implementation and maintenance of diagnostic and quality assurance standards;

•  develop educational resources for medical professionals and patients involved with organ transplantation

•  Provide strong networking opportunities and develop professional skills by sharing knowledge and experience with preexisting organizations

 
Annually, the COP meets face-to-face at the American Transplant Congress (ATC).  At this meeting, members of the COP can network, discuss future initiatives and volunteer for projects. 
 
Membership is open to anyone involved in the science and practice of transplantation. Non-AST members can participate for a one-year trial. After this period, non-members must join AST to continue participation in the COP.
 
If you are interested in becoming a member of the AST Transplant Diagnostics Community of Practice, please use the online form to submit your professional interest details and contact information. For more information visit, the AST Tx Dx COP website at http://www.a-s-t.org/cop/transplant-diagnostic-cop.

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ASHI sponsors Symposia at FOCIS 2011

Please join ASHI at the upcoming FOCIS 2011 for the satellite symposia on June 23rd in Washington, DC.  For details about FOCIS or the ASHI sponsored event please visit FOCIS.

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ASHI’s comments for the MEDCAC on “The Impact of ESA Use in Renal Transplantation” and “The Impact of Pre-Transplant Red Blood Cell (RBC) Transfusions in Renal Allograft Rejection.”

 

The Medicare Evidence Development & Coverage Advisory Committee (MEDCAC) held a January 19, 2011 hearing on “The Impact of Erythropoiesis Stimulating Agents (ESA) on Renal Transplant Survival.” Dr. Susie Leffell presented comments on ASHI’s behalf. To read her testimony, click here.

Following this hearing there was a February 3, 2011 deadline for comments on the technology assessment portion of “The Impact of Pre-Transplant Red Blood Cell (RBC) Transfusions in Renal Allograft Rejection.” The ASHI leadership submitted comments which will be reviewed and posted by May 3, 2011 at http://www.ahrq.gov/clinic/techix.htm. To read these comments now, click here.

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Mexico City Workshops

IMMUNOGENETICS:
Monday, July 25 – Friday, July 29

MOLECULAR GENETICS:
Monday, August 1 – Friday, August 5

For more information, click here click here.

For information about the agenda, click here.

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Membership Connection

Get connected with Facebook, Linkedin, and Twitter for the latest ASHI announcements and discussions regarding the association, education and events, and industry related topics. Don’t forget to check out the Eblasts Archives page for the latest e-mail blasts and the News Archives for the latests news postings to ASHI.

 

Facebook
http://www.facebook.com/pages/American-Society-for-Histocompatibility-Immunogenetics/147211865310535

 

Linkedin
http://www.linkedin.com/groupRegistration?gid=1878945&sharedKey=22ABC2119A72

 

Twitter
http://twitter.com/ASHI_HLA

 

News Archives
http://www.ashi-hla.org/news

 

Eblast Archives
http://www.ashi-hla.org/news/eblasts

 

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Home > ARB Release Form

ARB Release Form

Click here if the download does not automatically start.

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Shared Resources

Documents

Summary of the ASHI presentation at the FDA meeting on LDTs(Adobe PDF)

 

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Forms

Application Form For Continuing Certification (89KB, PDF)

Application Form for Provider Status (582KB, PDF)

Application Form for ABHI Laboratory Director Continuing Education (63KB, PDF)

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Annual Dues

The following is the current schedule for the ABHI's annual dues. Annual Dues for CHA, CHT, and CHS $45 Annual Dues for Histocompatibility Director $150

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Home > Provider Fee Schedule

Provider Fee Schedule

The ABHI approved provider fee schedule is provided in the table below.

Category	Provider	Fees or Corporate/Vendor Sponsorships	Program Hours	Fee
A	Laboratory/Organization/Society	No attendee registration fees, membership fees, or sponsorships collected	15 or fewer hrs per year	$50
B			More than 15 hrs per year	$100
C	Laboratory/Organization/Society	Program does collect registration fees, membership fees, or sponsorships	15 or fewer hrs per event	$175
D			More than 15 hrs per event	$350
E	Corporate, Commercial, Vendor	Sponsorship	10 or fewer hrs per program	$290
F			More than 10 hrs per program	$400
G	Organization/Society, Corporate, Commercial or Vendor	Not applicable	Offering same program at multiple venues	$600

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Home > Taking the Exam

Taking the Exam

Administering or Taking the Examination
The examination will be by computer at an AMP Assessment Center . Candidates do not need any prior computer experience or typing skills to take the examination. On the day of the examination, report to the Assessment Center no later than the scheduled testing time. Look for signs indicating AMP Assessment Center Check-in. A CANDIDATE WHO ARRIVES MORE THAN 15 MINUTES AFTER THE SCHEDULED TESTING TIME WILL NOT BE ADMITTED.

Identification
To gain admission to the Assessment Center , a candidate needs to present two forms of identification, one with a current photograph. Both forms of identification must be current and include the candidate's current name and signature. The candidate will be required to sign a roster for verification of identity. Acceptable forms of photo identification include a current driver's license with photograph, a current state identification card with photograph, a current passport, or a current military identification card with photograph. Employment ID cards, student ID cards and any type of temporary identification are NOT acceptable as the primary form of identification. CANDIDATES MUST HAVE PROPER IDENTIFICATION TO GAIN ADMISSION TO THE ASSESSMENT CENTER . Failure to provide appropriate identification at the time of the examination is considered a missed appointment. There will be no refund of the testing fee.

Rules for Examination
Security
AMP maintains test administration and test security standards that are designed to assure that all candidates are provided the same opportunity to demonstrate their abilities. The Assessment Center is continuously monitored by audio and video surveillance equipment for security purposes.

The following security procedures apply during the examination: Examinations are proprietary. No cameras, notes, tape recorders, personal digital assistants (PDAs), pagers or cellular phones are allowed in the testing room.

No programmable calculators are permitted. Only silent, hand-held, solar-or battery-operated calculators without paper tape-printing capabilities or alphabetic keypads, may be used. Financial calculators are allowed if they meet these specifications. Calculator malfunction during a test does not constitute grounds for challenging test scores or requesting additional test time. No guests, visitors or family members are allowed in the testing room or reception areas. No personal items, valuables, or weapons should be brought to the Assessment Center . Only keys and wallets may be taken into the testing room. AMP is not responsible for items left in the reception area.

Examination Restrictions
No personal belongings will be allowed in the Assessment Center . Pencils will be provided during check-in. The candidate will be provided with scratch paper to use during the examination, which must be returned to the supervisor at the completion of testing, or the candidate will not receive a score report. No documents or notes of any kind may be removed from the examination room. No questions concerning the content of the examination may be asked during the examination.

Eating, drinking or smoking will not be permitted in the Assessment Center . The candidate may take a break during the examination, but will not be allowed additional time to make up for time lost during breaks.

Misconduct
Individuals who engage in any of the following conduct may be dismissed from the examination, their scores will not be reported and examination fees will not be refunded. Examples of misconduct are when a candidate: creates a disturbance, is abusive, or otherwise uncooperative; uses electronic communications equipment such as pagers, cellular phones, PDAs; gives or receives help or is suspected of doing so; attempts to record examination questions or make notes; attempts to take the examination for someone else; or is observed with notes, books or other aids.

Copyrighted Examination Questions
All examination questions are the copyrighted property of ABHI. It is forbidden under federal copyright law to copy, reproduce, record, distribute or display these examination questions by any means, in whole or in part. Doing so may subject the candidate to severe civil and criminal penalties.

Practice Test
After the candidate's identification has been confirmed, he/she will be directed to a testing carrel. The candidate will be instructed on-screen to enter their Social Security number, and instructed on how to take their photograph which will remain on screen throughout the testing session. This photograph will also print on the score report.

Prior to attempting the examination, the candidate will be given the opportunity to practice taking a test using the computer. The time used for this practice test is NOT counted as part of the examination time or score. Once the candidate is comfortable with the computer testing process, he/she may quit the practice session and begin the timed examination.

Timed Examination
Following the practice test, the actual examination will begin. Before beginning, instructions for taking the examination are provided on-screen.

The computer monitors the time spent on the examination. The candidate will have 3.5 hours to complete the CHA, CHS, and CHT examinations and 5 hours to complete the Labratory Director examination. The examination will terminate if testing exceeds the time allowed. Click on the "Time" box in the lower right portion of the screen or select the Time key to monitor testing time. A digital clock indicates the time remaining to complete the examination. The Time feature may be turned off during the examination.

Only one examination question is presented at a time. The question number appears in the lower right portion of the screen. Choices of answers to the examination questions are identified as A, B, C, or D. The candidate must indicate his/her choice by either typing in the letter in the response box in the lower left portion of the computer screen or clicking on the option using the mouse. To change an answer, enter a different option by pressing the A, B, C, or D key or by clicking on the option using the mouse. The candidate may change his/her answer as many times as he/she wishes during the testing time limit.

To move to the next question, click on the forward arrow (>) in the lower right portion of the screen or select the NEXT key. This action will move the candidate forward through the examination question by question. To review any question, click the backward arrow (<) or use the left arrow key to move backward through the examination.

An examination question may be left unanswered for return later in the testing session. Questions may also be bookmarked for later review by using the mouse and clicking in the blank square to the right of the Time button. Click on the hand icon or select the NEXT key to advance to the next unanswered or bookmarked question on the examination. To identify all unanswered and bookmarked questions, repeatedly click on the hand icon or press the NEXT key. When the examination is completed, the number of examination items answered is reported. If not all questions have been answered and there is time remaining, return to the examination and answer those questions. Be sure to provide an answer for each examination question before ending the examination. There is no penalty for guessing.

Candidate Comments
During the examination, online comments may be provided for any question by clicking on the button displaying an exclamation point (!) to the left of the Time button. This opens a dialogue box where comments may be entered. Comments will be reviewed, but individual responses will not be provided.

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Statement of Competence

Statements of Competence for Histocompatibility Personnel (Adobe PDF)

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Applying

Submitting an application for the examination s
Complete the paper application included in the Candidate Handbook and mail it with the appropriate fee to ABHI, P.O. Box 19173 , Lenexa , Kansas 66285 -9173.  ABHI overnight address is: 18000 W. 105th Street, Olathe, Kansas  66061

The application is processed and a confirmation notice of eligibility is sent to the candidate within approximately two weeks. If a confirmation notice is not received within three weeks, contact the ABHI at 913/895-4602., ext. 4778.

Scheduling the examination and Administration Process
Once the candidate receives their confirmation notice he/she should immediately schedule an examination appointment at their convenience during the month in which they have applied. The confirmation notice contains a web address and toll-free telephone number for the candidate to contact AMP; ABHI’s testing agency. Appointments can also be scheduled online 24 hours a day, seven days a week at www.goAMP.com . The toll-free line is answered from 7:00 a.m. to 7:00 p.m. (Central Time) Monday through Thursday and 7:00 a.m. to 5:00 p.m. (Central Time) on Friday. The candidate must be prepared to confirm a date and location for testing and to provide her/his Social Security number as a unique identification number.

A candidate's eligibility and acceptance of the application is valid only during March or September. A candidate who fails to schedule an appointment for examination by the end of either month's eligibility deadline must re-submit a complete application including examination fee to schedule an examination appointment.

The ABHI examination is administered via computer at over 150 Applied Measurement Professionals (AMP) Assessment Centers geographically distributed throughout the United States and Canada . The international assessment centers that are available can be viewed at: http://www.goamp.com/AMP/Internationallocations.htm

The examinations are administered by appointment only Monday through Friday at 9:00 a.m. or 1:30 p.m. during the months of March and September . Individuals are scheduled on a first-come, first-served basis. Refer to the chart below.

Note: Examinations will not be offered on Labor Day.

If the candidate contacts AMP by 3:00 p.m. Central Time on...	Depending on availability, an examination may be scheduled beginning...
Monday	Thursday
Tuesday	Friday
Wednesday	Monday
Thursday	Tuesday
Friday	Wednesday

The candidate must contact AMP to schedule an appointment and will be given the specific time to report to the center. No admission ticket will be issued; therefore, the specified examination location, date and time should be noted. Candidates who arrive at the Assessment Center later than 15 minutes from the scheduled appointment time will not be admitted. Unscheduled candidates (walk-ins) will not be admitted to the Assessment Center .

ABHI reserves the right to verify information supplied by the candidate. An application is considered complete only if all requested information is complete and accurate; if the candidate is eligible for the examination; and if fees are submitted. Examination fees for ineligible applications will be refunded minus a $50 processing fee.

Computerized Version Appointment Changes
A candidate may reschedule ONE appointment for the computerized version of the examination at no charge by calling AMP at 888/519-9901 at least four business days prior to the scheduled testing session. (See table below.)

If an examination is scheduled on...	The candidate must call AMP by 3:00 p.m. Central Time to change his/her reservation by the…
Monday	previous Tuesday
Tuesday	previous Wednesday
Wednesday	previous Thursday
Thursday	previous Friday
Friday	previous Monday

A candidate who wishes to reschedule their examination but fails to contact AMP at least four business days prior to the scheduled testing session forfeits the application and all fees paid to take the examination. A complete application and examination fee are required to reapply for examination.

A candidate who cancels their examination after confirmation of eligibility forfeits the application and all fees paid to take the examination. A complete application and examination fee are required to reapply for examination. If a candidate must cancel an examination appointment or would like to request a refund due to a medical emergency the candidate must submit the request in writing accompanied by official written notification from attending physician to the ABHI Executive Office.

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Exam Fees

The following is the new schedule for the ABHI's examination application fees January 1, 2009. CHA and CHT Examination Application Fees $195 CHS Examination Application Fee $225 Histocompatibility Laboratory Director Examination Application Fee $890

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Exam Schedule

The ABHI Certification Examination for Associates, Technologists and Specialists will be offered in March and September . The examination will be administered by computer, and offered on any weekday during the months of March and September at over 150 assessment centers in the United States. There will be no specific pre-scheduled testing dates. Once a candidate’s eligibility is confirmed he/she will receive notice from the testing agency including instructions on how to schedule their examination appointment during March and September.  Test time for the Associates, Technologists and Specialists has been extended an additional 30 minutes allowing 3.5 hours to testing time.

The application deadlines will be January 1 and June 1 respectively for the CHA, CHS and CHT examinations.

The Histocompatibility Laboratory Director examination will be offered in September of each year. The application deadline will be June 1.

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Continuing Education

Only CHAs, CHSs, and CHTs who are due to recertify in the current year will be required to submit the completed application for Continuing Certification and documentation of CECs.  ABHI will no longer be reviewing every individual's CE activity each year. ABHI will review the CE Activity of only those individuals whose certification will be expiring at the end of the current year.  The application and documentation of activity will now be due to the ABHI Executive office by November 15 of the recertifying year.  All other ABHI certificants who are not within their recertifying year will be required to submit annual dues, notices will be released in December. 

Accepted CE Activities

Annual Dues

Approved Providers

CE Requirements

Forms

Provider Fee Schedule

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Examinations

 

Applying
Candidate Handbook
Exam Fees
Exam Matrices
Exam Schedule
Preparation
Statement of Competence
Taking the Exam

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2004

Search 1997-2005 Abstracts

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2005

Search 1997-2005 Abstracts

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Candidate Handbook

ABHI Candidate Handbook

American Society for Histocompatibility and Immunogenetics

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Related Links

Links to Resources and Useful Information

We hope you will use this collection of links for accessing resources and useful information. If you know of any useful resources related to our field, please send your suggestions . While we strive to check the validity of the links, web sites come and go, or move quite frequently. If any link operates incorrectly, please let us know so that it can be corrected.

Clinical and Transplantation
Government and Regulations
Immunology and Societies
Journals and Libraries
MHC and HLA
Molecular Biology and Genetics

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Clinical and Transplantation

clinical information and transplant organizations

• ABO Mismatch Reporting Center - accumulates and analyses available data with the aim to reach a deeper insight and to bring together those interested in ABO disparate transplantation. Great bibliography on ABO-mismatched transplants.
• AllergyImmunoLinx.com/Surgery/Transplantation Articles - a free, fast, and easy-to-use Web site designed to keep medical professionals informed of daily clinical developments. Each morning, the top Allergy and Immunology articles in surgery/transplantation and other specialties are aggregated from hundreds of premier medical journals.
• American Society of Transplantation
• Anthony Nolan Bone Marrow Trust [UK]
• Bone Marrow Donors Worldwide [The Netherlands]
• Bone Marrow Transplant Topics @ http://www.bmtinfo.org
• The Immune Tolerance Network (ITN) is an international clinical research consortium founded by the National Institute of Allergy and Infectious Diseases (NIAID), with additional support from the Juvenile Diabetes Research Foundation (JDRF), whose mission is to accelerate the clinical development of immune tolerance therapies. The ITN develops, implements, and conducts trials of novel immune tolerance therapies in type 1 diabetes, autoimmune diseases, solid organ and islet transplantation, and allergy and asthma. ITN trials look beyond the traditional endpoints of safety and efficacy, building into each trial a complementary set of genetic, cellular, and immunological studies that explore the underlying mechanisms of tolerance and disease.
• International Society for Hemotherapy & Graft Engineering (ISHAGE)
• International Pediatric Transplant Association - The International Pediatric Transplant Association (IPTA) is a professional organization of individuals in the field of pediatric transplantation.
• Medical Matrix-Guide to Internet Clinical Medicine Resources
• MedScape - a robust and integrated multi-specialty medical information and education tool. You may choose a personal Medscape home page from an assortment of specialty sites including Transplantation, primary care medicine sites, and nonclinical sites such as "Money & Medicine" or "Humor & Medicine." Requires a simple, one time, free registration. Excellent source for review of current medical literature, access to electronic journals, and CE programs (mostly free).
• National Marrow Donor Program (NMDP)
• NIAID Plan for Research on Immune Tolerance: Clinical Trials of Transplant Tolerance
• American Foundation for Donation and Transplantation (AFDT) (formerly SEOPF)
• TransplantHealth is a patient-oriented web site designed to provide transplant patients with information during the various stages of transplantation
• Transplant Pathology Internet Services (TPIS) at the University of Pittsburgh - a great source of transplant-related information and educational resources -- download the updated HLA Matchmaker Software by Rene Duquesnoy, Ph.D.
• Transweb: An Internet Resource Devoted to Transplantation and Donation
• UNOS

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Government and Regulations

CLIA, HCFA, OSHA, MSDS's, Federal Register and more

• Centers for Medicare and Medicaid Services (CMS, formerly HCFA)
• Federal Register - search for rules and regulations here.
• Analyte Specific Reagents - Final Rule (PDF). Requires free Acrobat Reader software.
• HIPAA Privacy Regulation Guidance - guidance on the final HIPAA regulations issued by HHS on 7/6/2001; full compliance by health care organizations, including labs, is required by 7/14/2003.
• MSDS Database at Vermont SIRI
• OSHA Information
• Cahaba Government Benefits Administrator - administers Medicare health insurance for the Centers for Medicare & Medicaid Services (CMS).
• Thomas: Legislative information (Library of Congress)

More Information on the Analyte Specific Reagent Rule:

• ASR Fact Sheet from the College of American Pathologists (CAP)
• Questions & Answers from the College of American Pathologists (CAP)
• "ASR: FDA Issues Final Rule" - an article by Jeffrey N Gibbs published in IVD Magazine, January 1998

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Immunology and Societies

Immunology resources and links to related organizations

• American Association of Blood Banks (AABB)
• American Association of Immunologists
• The Antibody Resource Page
• AMLI - Association of Medical Laboratory Immunologists
• ASCB - American Society for Cell Biology - this site has excellent information on public policy issues, such as discussions on human cloning and its impact on the practice of transplantation.
• ASEATTA - The Australasian and South East Asian, Tissue Typing Assoc. Inc. It has members in Australia, New Zealand, Hong Kong, Thailand, India, Singapore, Mongolia, Malaysia, The Phillipines, South Africa, Indonesia, Japan, the USA and New Guinea. [Australia]
• British Society for Histocompatibility and Immunogenetics (BSHI) [UK]
• Clinical Cytometry Society
• More about Corticosteroids [CH]
• Cyclosporin A images [UK]
• Cytokines Online Pathfinder Encyclopedia [DE]
• European Federation for Immunogenetics (EFI)
• Federation of Clinical Immunology Societies (FOCIS) - ASHI is now a participating society! See meeting announcement below.
• Immune Responses lecture guide
• Molecular Immunology - a great collection of immunology information and a wealth of links
• Images of Immunoglobulin Structures [UK]
• International Society for Analytical Cytology (ISAC)
• The Lymphatic System and Immunity
• Facts about Leukocytes and Mast Cells [CH]
• How Lymphocytes Produce Antibody - Cells Alive

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Journals and Libraries

tables of contents, abstracts and full-text articles; Medline

• Allergy and Clinical Immunology International , official journal of the World Allergy Organization, includes reviews and original articles on both clinical and research topics, association and meeting news, and a regular website review column. Currently, volumes from 1995 through the present are available online in full-text form free of charge.
• ASM Journals Online
• Blood & Marrow Transplant Newsletter is a not-for-profit organization that provides publications and support services to bone marrow, peripheral blood stem cell, and cord blood transplant patients and survivors.
• Clinical and Applied Immunology Reviews - table of contents
• Clinical and Experimental Allergy - tables of contents
• Clinical and Experimental Immunology - tables of contents
• Elsevier: Table of Contents of 900 journals including Human Immunology You can also sign up for the Table of Contents to be emailed to you directly each month. [The Netherlands]
• Entrez (Medline-Molecular Biology)
• European Journal of Immunogenetics - tables of contents
• Experimental and Clinical Immunogenetics - tables of contents
• Genes and Immunity - tables of contents
• HighWire Press - a service of Stanford University Libraries, is claimed to be the Earth's largest free full-text science archives
• Treatment Strategies - Hematology - a print and on-line eBook publication that provides the readership with a collection of comprehensive and thought provoking articles from the most respected key opinion leaders, leading doctors and authorities in the field.

Human Immunology Online! - tables of contents and abstracts; full-text and PDF format are available to ASHI members for downloading

• Immunity
• Immunogenetics - tables of contents and abstracts; full-text is available in PDF format for registered users
• Immunology - tables of contents
• International Digital Electronic Access Library - IDEAL is a developmental project of Academic Press, aiming to greatly expand and improve access to a large number of scientific journals. Journal tables of contents and abstracts are freely available to anyone (guest login required). Authorized Users at sites within the licensed consortia of the project can view, search, print, and download complete articles in the Acrobat format.
• Journal of Biological Chemistry
• Journal of Immunology
• Journal of Molecular Biology [UK]
• Journal of Molecular Diagnostics
• Leukemia Insights Newsletter from the M.D. Anderson Cancer Center - a source of information on Bone Marrow transplantation.
• National Library of Medicine
• Nature
• Nature Immunology - access to first two issues free; register for free access to tables of contents
• New England Journal of Medicine
• Reviews in Immunogenetics [DK] - tables of contents and sample full-text issue
• Science
• "The Scientist" On line
• Seminars in Immunology - tables of contents and abstracts
• Search Medline free through the National Library of Medicine:
  • PubMed
  • Medline provides free access to MEDLINE, sets of related articles pre-computed for each article cited in MEDLINE, and linkages to publishers' sites for full-text journals. At least 24 journals available, some by subscription only.
  • MEDLINEplus has extensive information from the National Institutes of Health and other trusted sources on over 500 diseases and conditions. There are also lists of hospitals and physicians, a medical encyclopedia and dictionaries, health information in Spanish, extensive information on prescription and nonprescription drugs, current health news, and links to thousands of clinical trials.
• Scandinavian Journal of Immunology - tables of contents
• Tissue Antigens [Denmark]
• Transplantation
• Virtual Library-Immunology

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MHC and HLA

immunogenetics, MHC, HLA and disease association resources

• Allele Frequencies in Worldwide Populations
• Birkbeck College XRay Crystalography images
• HLA Class I and Class II Sequence Data at the Anthony Nolan Research Institute [UK]
• HLA Gene and Haplotype Frequencies in the North American Population : The National Marrow Donor Program Donor Registry
• HLA and Disease Resources :

    HLA-B27 and Spondyloarthropathy

Select Entries from OMIM

    Mechanisms of HLA Association in Disease from the Institute of Transplantation Immunology [Norway]

    Rheumatic Diseases A nice lecture outline from Temple University

    Major Histocompatibility Complex and Rheumatoid Arthritis

A Cutting Edge Article for RHEUMA21ST by Editor Robert F. Willken

• IMGT/HLA Database - The IMGT/HLA Database is part of the international ImMunoGeneTics IMGT project and provides a specialist sequence databases for sequences of the human major histocompatibility complex (HLA). This includes all official sequences for the WHO HLA Nomenclature Committee For Factors of the HLA System. Development of this database has been undertaken by James Robinson, Julia G Bodmer and Steven GE Marsh. [UK]
• Immunogenomic Data-Analysis Working Group (IDAWG)
• Online Mendelian Inheritance in Man (OMIM) - This database is a catalog of human genes and genetic disorders authored and edited by Drs. Moyra Smith, Victor A. McKusick and their colleagues at Johns Hopkins and elsewhere, and developed for the World Wide Web by NCBI, the National Center for Biotechnology Information. The database contains textual information, pictures, and reference information. It also contains copious links to NCBI's Entrez database of MEDLINE articles and sequence information. The following are direct links to MHC entries:
  • HLA-A
  • HLA-B
  • HLA-C
  • HLA-DMA
  • HLA-DMB
  • HLA-DNA
  • HLA-DOB
  • HLA-DPA1
  • HLA-DPB1
  • HLA-DQA1
  • HLA-DQB1
  • HLA-DR
  • HLA-E
  • HLA-G
  • HLA-H

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Molecular Biology and Genetics

databases, protocols and other resources for molecular genetics

• Association for Molecular Pathology Homepage - source for info on clinical application of molecular biology techniques with links to related sites.
• ATCC - The American Type Culture Collection - search this catalog to find available cell lines.
• The Comprehensive Protocol Collection (CPC) from Dartmouth U.
• Genome Database-Home Page
• The ImMunoGeneTics Database ,IMGT, is an integrated specialised database containing nucleotide sequence information of genes important in the function of the immune system, including the B cell antigen receptor (Immunoglobulin or Ig), the T cell antigen receptor (TcR) and the class I and class II genes of the Major Histocompatibility Complex (MHC). [FR]
• National Center for Genome Resources
• PCRLinks - a website that provides selected Internet resources about the Polymerase Chain Reaction Technique.
• Search GenBank
• Sequence Submission Forms and Data Retrieval

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Home > Press Policies

Press Policies

The American Society for Histocompatibility and Immunogenetics (ASHI) welcomes press coverage of its major meetings, specialty conferences, and regional educational workshops. Representatives from recognized news organizations or publications are cordially invited to attend scientific sessions at these events for the express purpose of gathering news and information to produce editorial coverage of the meetings.

In addition to the Annual Meeting, ASHI holds a series of educational workshops and specialty meetings throughout the year. The following policies and guidelines have been prepared for news media interested in covering these meetings. If you have any questions regarding policies or available resources, please contact ASHI’s communications manager at . We look forward to working with you.

Complimentary registration is available to representatives of print, electronic and Internet general interest media and healthcare trade media (collectively known as press). To register as press, journalists must contact ASHI’s communications manager at least two weeks in advance of the meeting. There will be no on-site media registration available.

Journalists may attend the conference and report about research presented at the meeting, only if they have prior approval from the scientists presenting the research. Registration for the Annual Meeting, educational workshops or special conferences will be coordinated through ASHI’s communications manager.

To qualify as press, journalists must present media identification or a business card issued by a recognized news organization in addition to two bylined medical articles. Freelance journalists must also present a letter of assignment on letterhead from a recognized news organization or publication.

Journalists working for medical publishing companies must have appropriate press credentials (i.e., proof of an editorial assignment) in order to register and the publication must meet the following criteria:

- Must have multiple sponsors (no single-sponsor publications)
- Must have complete editorial freedom from their sponsors
- Exhibitors will not be allowed to register as press unless they can provide proof of an editorial assignment

Journalists reporting for online media outlets who wish to register as press must work for news-making organizations that meet the following criteria:

- The Web site must provide original, editorial news coverage
- Editorial content must be independent of advertising and sponsorship
- Advertising on the Web site must be clearly identifiable as such
- Any sponsors of the Web site should be clearly identified as such and should be multiple in number (i.e., no single-sponsored Web sites)

No filming or photography is allowed during any of the program sessions, including general sessions, symposia, workshops, and oral or poster presentations.

All news releases regarding presentations made at the specialty conferences must indicate that they are embargoed for release at the date and time the data are presented at the meeting.

Reporters, producers and editors agree to the embargoes and release times stated on the news releases and other materials. Failure to abide by the embargoes will result in suspension of credentials, which will affect attendance at the current and future conferences and ability to receive advance press materials.

Information regarding media registrants is proprietary. ASHI does not make available press registration lists.

Media events or news briefings other than those organized by ASHI are not permitted in any ASHI meeting areas without prior consent from ASHI’s communications manager.

ASHI reserves the right to bar from this and future meetings any journalist who deliberately promotes the viewpoint of one company or institution, or who attempts to solicit manuscripts, advertising, or subscriptions from registrants or exhibitors.

For more information regarding ASHI specialty conferences please contact:

Communications Manager
American Society for Histocompatibility and Immunogenetics
15000 Commerce Pkwy., Suite C
Mt. Laurel, NJ 08054
Telephone: 856-642-4420
Email:

*Please note that smoking is not permitted in meeting areas or at other ASHI events.

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Home > Related Meetings

Related Meetings

2012 Meeting Dates

16th International HLA and Immunogenetics Workshop and Conference

For more information: http://www.16ihiw.org

Joint IHWS/EFI/BSHI Conference

May 28 - June 3, 2012 Liverpool

For more information: http://ihiwefibshi.org/

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FOCIS 2012

June 20 - June 23, 2012
Vancouver, BC, Canada

For more information: http://www.focisnet.org/FOCIS/index.php?option=com_content&view=article&id=37&Itemid=31

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American Foundation for Donation & Transplantation (AFDT) 

16th Histocompatibility Specialist Course
June 22-30, 2012
New York, New York Hotel & Casino in Las Vegas, NV
http://www.amfdt.org

The curriculum is designed for senior technologists and new laboratory directors involved in the day to day management and development of the
histocompatibility laboratory. Applicants should have a background in immunology, Immunogenetics and histocompatibility.
Cost: $1,500
Hotel per weeknight: $69++; weekend: $99++
Registration to start January 2012

For more information: Contact: Arlene Skinner, 800-kidney9,

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APHIA

The 9th International Summer School on Immunogenetics

11th - 13th November 2012
Victor Harbor - South Australia
Whaler's Inn Resort

For accomodations visit www.bluffview.com.au.

 

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Home > Membership & Lab Directory

Membership & Lab Directory

ACCREDITED LABORATORIES
A listing of Accredited Laboratories may be found in the Accreditation section of the Lab Center.

 

MEMBERSHIP DIRECTORY
The ASHI Membership Directory is a copyrighted document that is not for commercial use.  It may be used for personal or professional use. It is available in two formats. 

PDF  MEMBERSHIP DIRECTORY (for downloading)
The PDF version of the directory is published annually and is available to ASHI members upon request.  For the most up-to-date information, please use the searchable online directory provided below. Request can be made by emailing .

SEARCHABLE ONLINE DIRECTORY (online search)
For the most up-to-date directory information, please use the search box listed below.

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Home > White Papers

White Papers

• Pre-Transplant Assessment of Donor-Reactive, HLA-Specific Antibodies in Renal Transplantation: Contraindication vs Risk (pdf, 107KB)

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Home > ASHI Quarterly

ASHI Quarterly

Articles printed in ASHI Quarterly

The ASHI Quarterly is a newsletter published to communicate information to the membership regarding Society activities, and clinically-relevant scientific articles of interest to the histocompatibility and immunogenetics community.  Issues addressed include updates on the activities of the Accreditation Program, new governmental regulations, summaries of the annual meeting and regional workshops, new product updates, literature reviews, and a classified section with position announcements. An ASHI Quarterly subscription is included as a membership benefit to all full, associate, institutional and sustaining members.

Tables of Contents for the Scientific Communications presented in each issue. Click on the volume number to view the list of articles.

Volume 36, Number 1 (2012)

• President's Column, Amy B. Hahn, PhD, D(ABHI)
• From the Editor-in-Chief, Thalachallour Mohanakumar, PhD
• The Role of Chromatin in Cytomegalovirus Latency and Reactivation
• Importance of Optimizing Pronase Treatment to Eliminate Rituximab Interference in B Cell Crossmatching
• My Life in HLA
• ASHI Board of Directors Meeting Summary
• A Response to "ASHI PT Survey Sample, AC 432: A Challenge"
• Call for ASHI Board Nominations - 2012
• ASHI Congratulates Recent ABHI Certificants
• PT Program Update Common Mistakes and How to Avoid Them
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by June 1, 2012)
• Scientific Communications

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Volume 35, Number 4 (2011)

• President's Column, Amy B. Hahn, PhD, D(ABHI)
• From the Editor-in-Chief, Thalachallour Mohanakumar, PhD
• HLA-G Regulation in Cancer: A Mystery Yet to be Resolved
• Biology and Function of CD4+ Regulatory T Cells: How Close are We to Translating into Clinical Application?
• Board of Directors Meeting Summary
• 2011-2012 Board of Directors
• Reflections on Resolution and Accuracy as New UNOS Typing Guidelines Are Up for Public Comment
• ASHI PT Survey Sample AC 432: A Challenge
• ASHI Proficiency Testing Program Update
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by March 15, 2012)

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Volume 35, Number 3 (2011)

• President's Column, Geoffrey A. Land, PhD
• From the Editor-in-Chief, Thalachallour Mohanakumar, PhD
• Luminex-based Single-antigen-bead Testing: Explanation and Solution for the Prozone Phenomenon
• Do FY Antigens Act as Minor Histocompatibility Antigens in the Graft-Versus-Host Disease Paradigm After Human Leukocyte Antigen-Identical Sibling Hematopoietic Stem Cell Transplantation?
• ASHI 2011 Regional Meetings Highlights
• Board of Directors Meeting Summary
• 2010 Year End Financial Summary
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by December 1, 2011)

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Volume 35, Number 2 (2011)

• President's Column, Geoffrey A. Land, PhD
• From the Editor-in-Chief, Maria P. Bettinotti, PhD
• A New PCR-SSP Method for HLA DR-DQ Risk Assessment for Celiac Disease
• Anti-HLA Antibody Testing and its Clinical Application: The Japanese Red Cross Tokyo Blood Center Experience
• Our Experience in Expanding SBT Typing to Include Solid Organ HLA Typings
• Meeting Report: HLA Epitopes in Clinical Transplantation
• Proficiency Testing Program News
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by September 30, 2011)

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Volume 35, Number 1 (2011)

• President's Column, Geoffrey A. Land, PhD
• From the Editor-in-Chief, Maria P. Bettinotti
• ABO-Incompatible Renal Transplantation
• Guidelines for Selection of Unrelated Adult Volunteer Donors for Hematopoietic Progenitor Cell Transplantation
• Update on the 16th International HLA and Immunogenetics Workshop Projects
• ASHI Board of Directors Meeting Summary
• Management Corner
• 2011 Call for Award Nominations
• 2011 Call for ASHI Board Nominations
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by June 1, 2011)

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Volume 34, Number 4 (2010)

• President's Column, Geoffrey A. Land, PhD
• From the Editor-in-Chief, Sharon Adams, MT, CHS(ABHI)
• HLA Alleles and Drug Hypersensitivity Reactions
• Pancreatic Islet Transplantation - Recent Progress
• Molecular Characterization of Human Neutrophil Antigen System 3 (HNA-3): New Opportunities to Prevent TRALI
• Scenes from 36th Annual Meeting
• ASHI Board of Directors Meeting Summary
• 2010-2011 ASHI Board of Directors
• Transplant Histocompatibility Conference Follow-up Meeting: Issues and Approaches to Consistency in HLA Antibody Testing
• Accreditation News
• ASHI Proficiency Testing Program News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by March 15, 2011)

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Volume 34, Number 3 (2010)

• President's Column, Marcelo Fernández-Viña, PhD, D(ABHI)
• From the Editor-in-Chief, Sharon Adams, MT, CHS(ABHI)
• Next Generation Sequencing: Entering a New Era in HLA Sequence-Based Typing.
• British Guidelines for the Detection and Characterization of Clinically Relevant Antibodies in Allotransplantation
• ASHI 2009 Financial Summary
• The Management Corner
• Accreditation News
• ASHI Proficiency Testing Program Update
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by December 1, 2010)

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Volume 34, Number 2 (2010)

• President's Column, Marcelo Fernández-Viña, PhD, D(ABHI)
• From the Editor-in-Chief, Sharon Adams, MT, CHS(ABHI)
• Establishment of a Local Sample Exchange to Ensure Crossmatch Consistency in a Multicenter, Multilaboratory Organ Procurement Organization
• The Role of the Histocompatibility Laboratory in Kidney-Paired Donation Programs
• The Usefulness of Artificial Neural Networks in Predicting the Outcome of Hematopoietic Stem Cell Transplantation: A Crystal Ball to Foresee the Future?
• Recent Articles in Pronase-treatment of Lymphocytes: A Review of Selected Current Literature
• Directors' Training and Review Committee Update
• ASHI 36th Annual Meeting
• Accreditation News
• Summary of ASHI Board of Directors Meeting
• ASHI Proficiency Testing Program Update
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by October 1, 2010)

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Volume 34, Number 1 (2010)

• President's Column , Marcelo Fernández-Viña, PhD, D(ABHI)
• From the Editor-in-Chief , Sharon Adams, MT, CHS(ABHI)
• Executive Director Letter "Community"
• An Update to HLA Nomenclature, 2010
• Single Chain MHC Class I Molecules as Modulators or Monitors of Immunity to Tumors, Pathogens and Transplants
• What’s Happening at http://www.allelefrequencies.net
• Summary of ASHI Board of Directors Meeting
• Summary of 2008 Joint Histocompatibility Conference
• 2010 Call for Award Nominations
• Quality Assurance and Standards Committee Activities
• Accreditation News
• ASHI Proficiency Testing Program Update
• ASHI-U Update "Living History: My life in HLA"
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by June 1, 2010)

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Volume 33, Number 4 (2009)

• President's Column , Marcelo Fernández-Viña, PhD, D(ABHI)
• From the Editor-in-Chief , Sharon Adams, MT, CHS(ABHI)
• Killer Immunoglobulin Receptors, Natural Killer Cells and Leukemia
• The Perfect Match? The Immunogenetics of Balancing Graft-versus-Host and Graft-Versus Leukemia in Hematopoietic Stem Cell Transplantation
• Has Solid Phase Testing for Alloantibody Moved us Ahead?
• Call for Board Nominations
• Summary of Board of Directors Meeting
• 2010 Board of Directors
• Accreditation News
• 16th International HLA and Immunogenetics Workshop
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by March 15, 2010)

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Volume 33, Number 3 (2009)

• President's Column , Deborah Crowe, PhD, D(ABHI)
• From the Editor-in-Chief , Sharon Adams, MT, CHS(ABHI)
• Natural Killer Cell Reconstitution and Outcome of Unrelated Donor Hematopoietic Stem Cell Transplantation
• Testing Platelet Donors for Leukocyte Antibodies
• Urine-based Biomarkers for Kidney Damage: Novel Assay for Monitoring Transplant Patients
• Board of Directors Meeting Summary
• ASHI 2008 Financial Summary
• Literature Review
• ASHI Staff Update
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by December 1, 2009)

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Volume 33, Number 2 (2009)

• President's Column , Deborah Crowe, PhD, D(ABHI)
• From the Editor-in-Chief , Sharon Adams, MT, CHS(ABHI)
• The Significance of HLA in Nasopharyngeal Carcinoma
• Alloimmune Responses Leading to Autoimmunity: Role in Chronic Rejection
• Ultraspecific Probes for High Throughput HLA Typing
• The Value of Volunteerism
• Natural Killer Cells in Solid Organ Transplantation: A Review of Selected Current Literature
• Accreditation News
• ASHI-U Update
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by September 1, 2009)

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Volume 33, Number 1 (2009)

• President's Column , Deborah Crowe, PhD, D(ABHI)
• From the Editor-in-Chief , Sharon Adams, MT, CHS(ABHI)
• Understanding Pre-Infection CD8+ T Cell Repertoires is Required for the Design of a T Cell HIV Vaccine
• Solid-Phase Anti-HLA Screening for Transplantation: The Pros and Cons of Available Methods
• Be Your Lab's Sherlock Holmes: Fingerprint Your Patient's Serum Profile
• Board of Directors Meeting Summary
• Recent Articles in Immunogenetics and Histocompatibility: A Review of Selected Current Literature
• "What's Hot" at the 34th Annual ASHI Meeting
• Call for Board Nominations
• Call for Award Nominations
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by June 1, 2009)

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Volume 32, Number 4 (2008)

• President's Column , Deborah Crowe, PhD, D(ABHI)
• From the Editor-in-Chief , Sharon Adams, MT, CHS(ABHI)
• Meeting the "Multi" Challenges for Quantitative Chimerism Testing: Multi-Donor and Multi-Lineage Analysis after SCT
• Distinguishing DRB1*1401 and DRB1*1454
• Quality Assurance and Standards Update
• Board of Directors Meeting Summary
• 2008–2009 Board of Directors
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by March 1, 2009)
• 34th Annual Meeting: Scenes from Toronto

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Volume 32, Number 3 (2008)

• President's Column , Carol Pancoska, PhD, D(ABHI)
• From the Editor-in-Chief , Sharon Adams, MT, CHS(ABHI)
• Successful Use of Bioinformatics to Identify Broadly Immunogenic HLA Class I Restricted T-cell Responses against HIV
• Neutrophil Antibody Testing
• Involvement of the HLA Genetic Diversity in Schizophrenia: Supporting Data and Perspectives
• Summary of Board of Directors Meeting
• ASHI 2007 Financial Summary
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members – must be submitted by December 1, 2008)

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Volume 32, Number 2 (2008)

• President's Column , Carol Pancoska, PhD, D(ABHI)
• From the Editor-in-Chief , Sharon Adams, WT, CHS(ABHI)
• Introduction to BioArray Solutions' BeadChip Technology
• Got Milk? A Simple Method for Reducing the Undesirable Effects of Pronase Treatment of Lymphocytes
• In Silico Resolution of Ambiguous HLA Typing Data
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by September 1, 2008)

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Volume 32, Number 1 (2008)

• President's Column , Carol Pancoska, PhD, D(ABHI)
• From the Editor-in-Chief , Sharon Adams, WT, CHS(ABHI)
• Optimizing Natural Killer Activity in Allogeneic Stem Cell Transplantation
• A Quality Management System for HLA Laboratories
• The Future of Immunogenetics – Relevance to HLA
• ABHI Exam Schedule
• Summary of Board of Directors Meeting
• Accreditation News
• 2008 Call for Board Nominations
• 2008 Call for Award Nominations
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by June 1, 2008)

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Volume 31, Number 4 (2007)

• President's Column , Carol Pancoska, PhD, D(ABHI)
• From the Editor-in-Chief , Francesco M. Marincola, MD
• Update on HLAMatchmaker: A Molecularly Based Algorithm for Histocompatibility Determination at the Epitope Level
• Non-HLA Genomics and Allo-transplant Outcome
• Cord Blood Transplants in the Absence of Immune Suppression:A Potential Stem Cell Source for Regenerative Medicine
• ABHI Exam Schedule
• Summary of Board of Directors Meeting
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by March 1, 2008)

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Volume 31, Number 3 (2007)

• President' s Column , Karen Nelson, PhD, D(ABHI)
• From the Editor-in-Chief , Francesco Marincola, MD
• A Web-Based Program for Pyrosequencing Primer Design
• HLA Class II Antibodies in Potential Renal Transplant Recipients
• An Innovative Twist in Transplanting Multiple Patients
• Accreditation Update
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by December 1, 2007)

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Volume 31, Number 2 (2007)

• President' s Column , Karen Nelson, PhD, D(ABHI)
• From the Editor-in-Chief , Francesco Marincola, MD
• HLA in North Africa: From Population Studies to Clinics at
  the Bridge Between Europe and Sub-Saharan Africa
• Renal Transplantation in African Americans:
  The Impeding Factors
• Hurricane Katrina and the LSU Immunocytogenetics
  Laboratory:Actions Taken and Lessons Learned
• Accreditation Update
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by September 1, 2007)

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Volume 31, Number 1 (2007)

• President' s Column , Karen Nelson, PhD, D(ABHI)
• From the Editor-in-Chief , Francesco Marincola, MD
• Is it a Novel HLA Allele? How to Identify, Confirm and Report Novel HLA Alleles
• Clinical Aspects of MICA
• Quantitative Real Time PCR: A Rapid and Sensitive Screening Method
• Summary of ASHI Board of Directors Meeting
• Accreditation News
• Call for Nominations
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by June 1, 2007)

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Volume 30, Number 4 (2006)

• President' s Column , Karen Nelson, PhD, D(ABHI)
• From the Editor-in-Chief , Francesco Marincola, MD
• The Idiopathic Inflammatory Myopathies (IIM)
• KIR and Population Studies
• Immunogenetic Markers and the Sporadic Alzheimer’s
  Disease Diagnostic Knot
• Review of Post-Transplant Immune Monitoring Survey
• 2007 Board of Directors
• Board of Directors Meeting Summary
• Accreditation Update
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by March 1, 2007

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Volume 30, Number 3 (2006)

• President' s Column , Peter Nickerson, MD, FRCPC
• From the Editor-in-Chief , Francesco Marincola, MD
• Significance of Non-MHC Antibodies in Transplantation
• Leukocyte Antibodies and Transfusion Reactions
• Impact of Host and Viral Diversity on HIV-specific T cell Responses
• Summary of Board of Directors Meeting
• 2005 Year End Audit Summary
• ASHI University Regional Meetings, Class Of 2006
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by December 1, 2006)

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Volume 30, Number 2 (2006)

• President' s Column , Peter Nickerson, MD, FRCPC
• From the Editor-in-Chief , Francesco Marincola, MD
• UNOS Update
• Disease Predisposing Genes in the Extended Major Histocompatibility Complex
• Identifying Associations Between HLA Type and Severity of Autoimmune Lymphoproliferative Syndrome
• Polymorphism in Clinical Immunology
• ASHI Committee Updates
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by September 1, 2006)

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Volume 30, Number 1 (2006)

• President’s Column , Peter Nickerson, MD, FRCPC
• From the Editor-in-Chief , Francesco Marincola, MD
• New Advances in the Immunogenetics of Hashimoto’s Thyroiditis
• The Role of Regulatory T-cells in Transplantation Tolerance
• The Immunogenetics of Psoriasis
• Summary of Board of Directors Meeting
• Accreditation News
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by June 1, 2006)

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Volume 29, Number 4 (2005)

• President’s Column
• Accreditation News
• Early History of Transplantation Immunology: Part II
• Proteomics: Bridging the Genome and the Bed Side
• Magic Matches: Unrelated-donor Transplants Facilitated by the National Marrow Donor Program
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by March 1, 2006)

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Volume 29, Number 3 (2005)

• President's Column
• Early History of Transplantation Immunology: Part I
• Virus-like Particles (VLPs) as Anti-viral Vaccines: An Effective
  Approach for an HIV-1 Vaccine Strategy
• KIR Gene Allele Diversity
• Summary of Board of Directors Meeting
• ASHI 2004 Financial Summary
• ABHI Update
• Summary of the 2005 Regional Workshops
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by December 1, 2005)

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Volume 29, Number 2 (2005)

• The President's Column
• ABHI Update
• Accreditation News
• The IMGT/HLA Sequence Database and the Immuno Polymorphism Database
• From MAC to MIC: MHC Class I Genes Come Full Circle
• HLA Typing of Volunteers for a Hematopoietic Stem Cell Donor Registry: Ensuring and Maintaining Quality of the NMDP Registry
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by September 1, 2005)

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Volume 29, Number 1 (2005)

• The President's Column
• ABHI Update
• Accreditation News
• ASHI Web Site Update
• Assays with HLA Antigens Attached to Polystyrene Beads and How We Interpret and Use Them
• Cytokine Polymorphisms, Cancer Susceptibility, and Prognosis
• Role of CD103 in the Pathogenesis of Organ Allograft Rejection and Graft-versus-host Disease Pathology
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by June 1, 2005)

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Volume 28, Number 4 (2004)

• The President's Column
• ABHI Update
• Accreditation News
• Receptors Mediating Interactions Between Natural Killer Cells and Their Viral Associates
• Graft-versus-Leukemia Effects of Natural Killer Cells
• Paternity Testing: Benefits of the Marriage of Tissue Typing and STR Analysis
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by March 1, 2005)

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Volume 28, Number 3 (2004)

• The President's Column
• ABHI Update
• Accreditation News
• Guidelines for the Development of Joint Written Agreements
• Pathology of Acute Rejection in the Renal Allograft
• Transfusion-Related Acute Lung Injury (TRALI)
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by December 1, 2004)

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Volume 28, Number 2 (2004)

• The President's Column
• ABHI Update
• Accreditation News
• Neutrophil Antigens and Antibodies
• HLA and HIV: Implications for HIV Vaccine Design
• HLA-DP Alloantibodies
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by September 1, 2004)

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Volume 28, Number 1 (2004)

• The President's Column
• Question Corner
• Evolutions in Tumor Immunology: Directing Allogeneic Immune Cells Against Metastatic Cancers
• Liver Transplant-Associated Graft-versus-host Disease
• Signal Transduction via HLA Class I Molecules in Epithelial and Endothelial Cells
• STR-Based Chimerism Testing: Using "ChimerTrack" Interactive Graphics Software to Ease the Burden
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by June 1, 2004)

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Volume 27, Number 4 (2003)

• The President's Column
• Question Corner
• Genomic Diversity of Human Natural Killer Cell Receptors
• Ambiguous Allele Combinations in Sequence-based Typing
• Fc Gamma Receptors: A MAgic Link with the Outside World
• Johns Hopkins Comprehensive Transplant Center InKTP Program
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by March 1, 2004)

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Volume 27, Number 3 (2003)

• The President's Column
• Accreditation News
• High-throughput Genomics: An Emerging Tool in Biology and Immunology
• Transplantation Options for Type1 Diabetes
• Luminex
• The Possibilities and Realities of a Computerized HLA LAboratory
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by December 1, 2003)

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Volume 27, Number 2 (2003)

• The President's Column
• Accreditation News
• HLA and Nasopharyngeal Carcinoma: 30 Years On
• From Nomenclature to Biochemistry
• Antibody Screening Beyond Tears
• Summary of Humoral Rejection Conference
• ASHI Quarterly Continuing Education Quiz (Free CEUs for ASHI Members - must be submitted by September 1, 2003)

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Volume 27, Number 1 (2003)

• The President's Column
• Letter from the Editor-in-chief
• Detecting Donor-Reactive Immune Regulation in Transplant Patients
• Amazing Arrays: Unraveling the Transcriptsome in Transplantation
• Applying Pyrosequencing To HLA-Typing
• Question Corner

---

Volume 26, Number 4 (2002)

• The President's Column
• Letter from the Editor-in-chief
• The Clinical Relevance of Non-HLA Polymorphisms in Transplantation
• The Study of Polymorphism in Cytokine and Cytokine Receptor Genes
• HLA Typing Using Reference Strand Conformation Analysis (RSCA)
• National Kidney Allocation in the UK - Issues for Histocompatibility and Immunogenetics Laboratories
• Summary of the ASHI Council Meeting
• Accreditation News
• Question Corner

---

Volume 26, Number 3 (2002)

• A New Allele Frequency Database
• Molecular HLA Class I Typing for UNOS Laboratories
• HLA-G - An Ace Up the Sleeve?
• Immunotracking of Specific Cancer Vaccine CD8 Lymphocytes
• Editorial: A Strategy to Initiate Post-transplant Antibody Testing

---

Volume 26, Number 2 (2002)

• HLA and Platelet Transfusion Outcome
• HLA Matchmaker: A Molecularly Based Algorithm for Histocompatibility Determination (sorry, file too large to download - 21MB)
• Polymorphism and Antigenicity of HLA-MICA
• Diversity of NK Cell Receptors and Their HLA Class I Ligands
• Tech Tips: Effects of Thymoglobulin on Immune Monitoring and Crossmatch Interpretation
• Editorial: A National Conference to Analyze the Wait List for Kidney Transplantation

---

Volume 26, Number 1 (2002)

• Dissecting Tumor Antigen-Specific CD8 T Cell Responses in Cancer Patients
• Natural Killer Cell Repertoires: Defining a New Role for MHC Class I Molecules
• Bone Marrow Infusion for Tolerance Induction in Clinical Organ Transplantation
• Tech Tips: Elimination of Prospective Crossmatching . . .
• MHC Tetramers for Monitoring CMV Response

---

Volume 25, Number 4 (2001)

• Editorial: PRA and Crossmatching - Should We Raise the Bar?
• Monitoring of Cytotoxic T Cells by HLA Class I Tetramers

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  Professional Standards

  Division of Professional Standards: Quality Assurance & Standards Committee, Proficiency Testing Committee, Directors Training Review Committee, Accreditation Review Board (click link to download or view)

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  Science and Education

  Division of Science and Education: Scientific Affairs Committee, Education Committee, Program Planning Committee
  (click link to download or view)

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  Membership Services

  Division of Membership Services: Membership Committee, Technologists Affairs Committee, Directors Affairs Committee, International Affairs Committee, Bylaws Committee, Awards Committee, Rose Payne Committee, Outstanding Technologist Committee, J. Marilyn MacQueen Committee
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  Communications

  Division of Communications: Publications Committee, Web Committee
  (click link to download or view)

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  Operations

  Division of Operations: Finance & Audit Committee, Nominations Committee, External Affairs Committee, Corporate Development Sub-Committee
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  Careers

  Template!

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  Standards

  2012 ASHI Standards with Guidance
  

   

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  Questions & Feedback

  Use this page to share your ideas for enhancing the ASHI Accreditation Program.

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  Home > ARB Appeals Process

  ARB Appeals Process

  Background and Introduction

  The ASHI Laboratory Accreditation process involves a multilevel evaluation by a Commissioner, Co-Chair, and, on alternate years at a minimum, an on-site Inspector. The final review is performed by and the outcome of the evaluation determined by the entire Accreditation Review Board that is comprised of the Program Director who serves as a non-voting chair (except when a tie-breaker is needed), the Co-Chairs, and the Commissioners. The structure of this process provides a high assurance of a thorough, fair, and impartial evaluation of compliance with the minimum standards that must be followed to assure reliable test results. Nonetheless, when accreditation is denied, revoked, suspended or limited, the applicant shall have the opportunity to appeal the decision.

  Exceptions: Applicants who refuse to cooperate with reasonable requests for information, data, or documentation; who deny an inspector access to the laboratory for purposes of performing an on-site inspection; or who knowingly and willfully obstruct the evaluation process shall not have the right to appeal the Accreditation Review Board’s decision.

  Description of the Process

  When there is NOT a condition of immediate threat to patient care or danger to the general public, the Appeal Process occurs in two stages.

  First, the Appeal Board reviews documents submitted by the applicant and the laboratory evaluation documentation to determine if an Appeal Hearing is warranted. A hearing is warranted when there is clear evidence suggesting the decision of the Accreditation Review Board resulted from bias, misrepresentation, or unavailability of critical information. If the Appeal Board determines that a hearing is not warranted, the initial decision of the ARB is upheld and the Appeal Process ends. If the Board determines that a hearing is warranted, the process moves to a second stage in which a hearing is conducted. For purposes of the hearing, the Appeal Board may request additional documentation from any members of the ARB, the inspector (s), or the applicant, which must be provided if the Appeal is to proceed. The Appeal Board will meet and will conduct interviews of relevant individuals either at the meeting site or by teleconference. Subsequent to the hearing and within 30 days of the filing of the appeal, the Appeal Board will render its decision. In cases in which the ARB has assessed there to be a threat to patient care or danger to the general public, the process must be completed within 10 calendar days of the notification of the applicant. The Appeal must be submitted within 5 days and the Appeal Board will review and render a decision within 10 days. In these cases, an appeal does not stay the decision of the ARB.

  All documents associated with the hearing shall remain confidential. The applicant shall receive a summary statement of the basis of the Appeal Board’s decision. If the Appeal Board upholds the initial decision of the ARB, the action of the ARB will be imposed immediately and the applicant shall be billed for all costs associated with he appeal process. These costs will include but are not necessarily limited to: phone calls, photocopying, personnel costs, shipping, legal fees. If the Appeal Board reverses the decision of the ARB, accreditation will be granted or renewed retroactive to the previous renewal.

  Materials and testimony are to be limited to documentation of conditions existent at the time of the laboratory evaluation. No actions taken and no data generated subsequent to the evaluation are to be considered. The evaluation process itself is not to be evaluated but rather whether or not the findings of the ARB were correct and factual. The decision of the Appeal Board shall be final.

  For an appeal application to be valid, it must contain all necessary documents and a check or money order to cover the filing fee. One-third of the filing fee is a non-refundable processing fee. If the Appeal Board finds against the applicant, part or all of the remaining two thirds of the filing fee will be applied to the cost of the Appeal Process. If the Appeal Board finds in favor of the applicant laboratory, two thirds of the filing fee will be returned to the applicant. If the application for an appeal is incomplete, the applicant will have 48 hours to submit the necessary materials or shall forfeit the right to an appeal.

  Instructions for Filing an Appeal

  Submit the following materials prior to the deadline for filing an appeal that was indicated on the Notice of Right to Appeal.

  1. Five copies of documents providing evidence that the findings of the ARB were incorrect. These materials must be page numbered, bear the lab’s ASHI number, and be bound together in a ring binder or other system that provides reasonable assurance of maintaining the order of the documents.

     The first page of the packet must be a table of contents.

     The front of each document must indicate the citation(s) address by the information/data contained in the document. This material must be limited to information about conditions that existed at the time of review and must not contain materials that discuss actions taken or data generated subsequent to the action of the ARB.

  2. A check, bank draft, or money order made payable to ASHI in the amount of $1500.
  3. A signed agreement of financial obligation.
  4. A written summary of no more than 2 pages in length, highlighting the bases of refuting the ARB decision.

  All materials must be sent by overnight courier and must be traceable.

  Send materials specified in A - D, above, to:
  Melissa (McElroy) Weeks
  Accreditation Manager
  ASHI Accreditation Office
  90 West County Road C
  Suite 300
  St. Paul, MN 55117
  (651) 487-2806 / Fax: (651) 489-3387
  

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  Home > Interim Packet Forms

  Interim Packet Forms

  Documentation

  The following forms are required for all laboratories renewing their ASHI Accreditation during the off cycle or interim years of the two-year Accreditation cycle.  To set up a new interim application, please contact ASHI's Accreditation Manager, Melissa Weeks () for assistance.

  Accreditation Review Program Interim Application Instructions (Adobe PDF)

  Accreditation Program Inspector Guidelines and Checklist (Adobe PDF)
  Including the most recent ASHI Standards for Histocompatibility Testing

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  Application Packet Forms

  New Applications Packet / Renewal Application Packet

  Documentation

  The following forms are examples of what is required for all laboratories seeking renewal Accreditation from ASHI, during the on-site cycle of their Accreditation.  To set up a new laboratory application, please contact ASHI's Accreditation Manager, Melissa Weeks () for assistance.

   

  "New ASHI Laboratory Checklist" (Adobe PDF)

  Accreditation Review Program On-Site Application Instructions (Adobe PDF)

  Accreditation Program Inspector Guidelines and Checklist (Adobe PDF)

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  Accreditation Process

  Levels of Review

  The inspection process involves three levels of review:

  1. The Inspector who inspects the labs and submits an inspection report to the laboratory Cirector and the Commissioner.

  2. The Commissioner who reviews first, the application packet completing a Commissioner’s Summary Form and secondly, the Inspector’s report and then notifies the laboratory Director of deficiencies. The Commissioner is the primary reviewer in the new process and is responsible for the assessment of compliance providing all facts as necessary.

     Commissioner Accreditation Timeline (.doc 33kb)

     Commissioner Accreditation Timeline (.pdf 43kb)

  3. The Accreditation co-Chair who acts as secondary reviewer.

     A fourth level of review by the Accreditation Review Board is used in all circumstances, to maintain fairness and consistency of all decisions and policies.

     The ASHI Board of Directors has oversight of the entire Accreditation process.

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  Home > Accreditation Application

  Accreditation Application

  This page contains the complete accreditation applications for new and existing laboratories. Click on the links above to download forms. Forms are in a PDF format and require the Adobe Acrobat reader. A link is provided for a free download of this software.

  Application Packet Updates

  Application packets are all online. When your laboratory cycle comes due, the Accreditation Manager will send your laboratory an email with a link to the application online, a password, and instructions. The information that you enter online will be stored in a database for years. This information creates a historical record of each laboratory's applications and will serve as the template for future application packets. Future packets will require only changes and updates to the stored information.

  Accreditation Cycles

  Each laboratory is assigned a cycle which will not change from year to year. Thus, deadlines remain constant within each cycle. New laboratories are assigned to a specific cycle based on when their application is submitted for review.

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  Home > Online Inspector Checklist

  Online Inspector Checklist

  You must be an approved ASHI Inspector with an assigned code to access this site in full.

  Online Inspector Checklist

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  Home > Online Interim Report

  Online Interim Report

  Please wait while we take you to the Online Interim Report. If you are not automatically redirected Online Interim Report.

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  Home > Validation Checklist

  Validation Checklist

  Please wait for your download to begin. If your download does not begin automatically begin within 10 seconds, click here to open.

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  Home > Accredited Laboratories

  Accredited Laboratories

  The list of ASHI Accredited laboratories is published by ASHI.  Laboratories are listed in alphabetical order by state. Contact information for each laboratory is provided as well as categories in which they are accredited. Updates and clarifications to this list may be addressed to Melissa (McElroy) Weeks, ASHI Accreditation Manager.

  Clicking on the following link will provide a listing of laboratories.

  Listing of ASHI Accredited Laboratories (Adobe PDF)

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  Inspection Schedule

  The Joint Commission has a policy of releasing certain organization-specific information to the public. One such item is the date(s) of the biennial on-site inspection (survey). The list below provides the timeframes in which specific laboratories are inspected.

  Laboratory Inspection Schedule

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  Inspector Training

  ASHI Inspectors serve as the first level of review in the Accreditation process. The Inspectors provide the hands-on evaluation of a laboratory. It is the goal of the Accreditation Review Board that inspectors provide consistent, objective evaluations of a laboratory. Thus, it is vital that inspectors are informed of changes in policies and regulations that can affect a laboratory's compliance. If you would like to become an inspector, please contact the Accreditation Manager to obtain an application.

  Requirements

  Appointment and Term

  1. Appointed by the Review Board.
  2. No set appointment time. Active in the computer database.

  Qualifications

  1. Employed by an ASHI Accredited laboratory.
  2. Willing to perform on-site visits in a timely, professional and confidential manner as a voluntary service to ASHI with reimbursement of usual and customary expenses.
  3. Attended one (1) full day training workshop since August 2002 and attended either an update session or completed an Accreditation self study program every other year. Attended one training session to perform the on-line inspection using the audit guide.
  4. Performed at least one site visit as a trainee.
  5. Meet or exceed the criteria of Histocompatibility General Supervisor as defined in the ASHI Standards. (See also, the Statements of Competence for Histocompatibility Personnel).
  6. Minimum of two (2) of the following for specific approved technologies: 1). CHS; 2). Diplomat; or 3) documented technical competency. The specific approved technologies include: serology, molecular, flow, solid phase and cellular.

  Responsibilities

  1. Perform inspections according to the guidelines in this manual.
  2. Submit to the Commissioner, a copy of the Inspector's Summary Form and the Inspector's Checklist. Electronic submission is immediate. Additional comments should be sent within 2 days.
  3. Notify the Commissioner whenever there may be a conflict of interest.
  4. Sign a Conflict of Interest and Statement of Confidentiality annually.

  Inspector Workshop Dates

  The next full day workshop will be at the ASHI Annual Meeting, Monday, October 8, 2012 in San Juan, Puerto Rico.  To register, contact Melissa Weeks by email: . 

  Date	Time	Who attends	Location
  October 8, 2012	8 am - 5 pm	All Inspectors	ASHI Annual Meeting 2012 - San Juan, Puerto Rico

   

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  Inspection

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  Policy Update

  The Accreditation Review Board meets three times per year to review laboratory applications and determine accreditation status. The board meets during the annual meeting to address administrative issues and polices with regards to changes in standards and other pertinent regulatory issues. As policies are adopted or changed, the junior Co-chair maintains the records. These polices have been approved by the ASHI Board of Directors. Updates will be posted quarterly. New policies since the last update will be designated as [New].

  ASHI ACCREDITATION PROGRAM POLICIES LIST

  ASHI ACCREDITATION PROGRAM POLICIES

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  Home > Directors’ Training Review & Credentialing

  Directors’ Training Review & Credentialing

  The process of evaluating new directors or directors seeking to add areas of accreditation and has been redefined by the Accreditation Review Board and the Directors Training Review and Credentialing Committee in accordance with current laboratory Standards of the American Society for Histocompatibility and Immunogenetics.

  The members of the Director Training Review Committee are listed below. Please contact them for any questions regarding Director Training Programs and portfolio reviews

  Chair: Angelo Arnold, PhD Director, Transplant Immunology Laboratory Westchester Medical Center 100 Woods Rd. Valhalla, NY 10595 Email:

  Vice-Chair: Paul R. Warner, PhD, D(ABHI) Puget Sound Blood Center Immunogenetics Lab 921 Terry Avenue Seattle, WA 98104-1256 Email:

  DTRC COMMITTEE MEMBERS

  • Geoffrey Land, PhD - ad hoc
  • Lawrence Jennings, MD, PhD
  • Yenhui Chang, MD, PhD
  • Philip Ruiz, MD, PhD
  • Diane Pidwell, PhD
  • Brian Susskind, PhD
  • Manish Gandhi, MD
  • Daniel Ramon, PhD
  • Neal den Hollander, PhD
  • John Gerlach, PhD (nonvoting)

  CRITERIA FOR MEMBERSHIP ON THE DIRECTOR TRAINING REVIEW COMMITTEE
  
  The candidate must:

  • be an ASHI member
  • have experience as an approved Laboratory Director
  • not be a member of the ASHI Foundation
  • sign a confidentiality agreement and a conflict of interest disclosure statement

  GUIDELINES FOR NEW DIRECTORS

  • Guidelines for Submission of Portfolios
  • Sample case file
  • Case file template
  • Case log template
  • Registration form

  APPLICANT PROCESS TIMELINE

  STEPS IN PROCEDURE	TIME
  1. Register with the Accreditation Manager	Clock Starts
  2. DTRC review of initial documentation**	Week 1-2
  3. Case profile development - Mentor communicates to DTRC	Week 3
  4. DTRC approval letter to begin training	Last of training
  5. Submission of case profiles	End 23 month
  6. Case Profile evaluation	24 month
  7. Oral interview	24 mon +3 wk
  8. DTRC decision letter	24 mon +3 wk
  9. Register for ABHI or similar approved board examination	As offered

   

  DIRECTOR TRAINING PROGRAMS

  New guidelines for the development and implementation of ASHI accredited Director Training Programs are available through the link below. These guidelines were approved by the ASHI Board in August 2011.
  

   

  Guidelines for Director Training Programs

  Criteria for Approval of Histocompatibility & Immunogenetics Training Programs

  ASHI-Approved Training Programs in Histocompatibility & Immunogenetics

   

  DTRC APPEALS PROCESS
  

  For instructions regarding filing an appeal, please click here.

   

   

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  Home > Review Board

  Review Board

  Michael Gautreaux, PhD, D(ABHI)
  Program Director (2012)
  Wake Forest University Health Sciences
  HLA/Immunogenetics Laboratory
  145 Kimel Park Dr., Suite 250
  Winston-Salem, NC 27103
  Business Phone: 336/716-4456
  Pager: 336/806-7972
  FAX Number: 336/774-7665
  Email:

   

  ---

  Co-Chairs

  Regions 1-4

  John Schmitz, PhD, D(ABHI)
  Co-Chair (2013)
  University of North Carolina Hospitals
  HLA Laboratory
  101 Manning Drive
  Room 1035 East Wing
  Chapel Hill, NC 27514
  Business Phone: 919/966-8453
  FAX Number: 919/966-0486
  Email:

  Regions 5-8

  Maurine Davidson, CHS
  Co-Chair (2012)
  University of Minnesota Medical Center
  Immunology Lab, Mayo Mail Code 724
  420 Delaware Street, SE
  Minneapolis, MN 55455
  Business Phone: 612/273-3100
  FAX Number: 612/273-7036
  Email:

  Regions 9-12

  Linda Buckert, MT(ASCP), SBB, CHS
  Co-Chair (2014)
  Loma Linda University Medical Center
  11234 Anderson Street
  Room 2125
  Loma Linda, CA 92354
  Business Phone: 909/558-4144
  FAX Number: 909/558-0144
  Email:

  ---

  Commissioners

  Region 1

  David F. Kiger, CHS
  Commissioner (2012)
  Wake Forest University Health Services
  145 Kimel Park Drive
  Suite 250, General Surgery
  Winston Salem, NC 27103
  Phone: 336/716-1816
  FAX Number: 336/774-7665
  Email:

  Region 2

  Nancy Higgins, MT, CHS
  Commissioner (2013)
  Indiana University Health Methodist
  Transplant Immunology Laboratory
  1812 N. Capitol Avenue
  Wile Hall 116
  Indianapolis, IN 46202
  Phone: 317/962-6194
  FAX Number: 317/962-6195
  Email:

  Region 3

  Ellen Klohe, PhD, D(ABHI)
  Commissioner (2012)
  Inland Northwest Blood Center
  HLA Laboratory
  210 W. Cataldo
  Spokane, WA 99201
  Business Phone: 509/232-4485
  FAX Number: 509/232-4528
  Email:

  ---

  Region 4

  Noureddine Berka, PhD, D(ABHI)
  Commissioner (2012)
  Calgary Laboratory Services
  Tissue Typing Laboratory
  9, 3535 Research Road NW
  Calgary, Alberta T2L 2K8 Canada
  Business Phone: 403/770-3655
  FAX Number: 403/770-3738
  Email:

  Region 05

  Myra Coppage, PhD, HCLD
  Commissioner (2012)
  University of Rochester Medical Center
  Pathology & Laboratory Medicine
  601 Elmwood Ave. Box 608
  Room 2-3659
  Rochester, NY 14642
  Business Phone: 585/275-0985
  FAX Number: 585/275-2436
  Email:

  Region 06

  Denise Owens, BS, CHS
  Commissioner (2013)
  VA Medical Center
  Iowa Regional Histocompatibility and
  Immunogenetics Laboratory
  601 Highway 6 West
  Iowa City, IA 52246
  Phone: 319/338-0581 ext. 5640
  FAX Number: 319/339-7032
  Email:

  ---

  Region 07

  Afzal Nikaein, PhD, HCLD
  Commissioner (2013)
  Texas Medical Specialty, Inc.
  7777 Forest Lane, Building C Suite 768
  Dallas, TX 75230
  Phone 1: 972/566-5761
  Fax: 972/566-7720
  Email:

  Region 08

  John Crawford, BS, CHS
  Commissioner (2012)
  University of North Carolina Hospitals
  HLA Laboratory
  101 Manning Drive
  Room 1035 East Wing
  Chapel Hill, NC 27514
  Business Phone: 919/843-0185
  FAX Number: 919/966-7897
  Email:

  Region 09

  Paul Sikorski, MS, CHS
  Commissioner (2013)
  Johns Hopkins University School of Medicine
  Immunogenetics Laboratory
  2041 East Monument Street
  Baltimore, MD 21205-2222
  Phone: 410/955-3600
  FAX Number: 410/955-0959
  Email:

  ---

  Region 10

  Medhat Askar, MD, PhD, D(ABHI)
  Commissioner (2012)
  Allogen Laboratories
  Cleveland Clinic Foundation
  9500 Euclid Ave
  Cleveland, OH 44195
  Business Phone: 216/444-5918
  FAX Number: 216/444-8261
  Email:

  Region 11

  Dean R. Sylvaria, BS, CHS
  Commissioner (2013)
  Beth Israel Deaconess Medical Center
  Histocompatibility Lab
  One Deaconess Rd, WCC-210
  Boston, MA 02215
  Phone: 617/754-3320
  FAX Number: 617/754-3288
  Email:

  Region 12

  Zahra Mehdizadeh Kashi, PhD
  Commissioner (2012)
  Kashi Clinical Laboratories
  10101 SW Barbour Blvd. Ste 200
  Business Phone: 503/206-4989 x201
  FAX Number: 503/206-6939
  Email:

  ---

  OMBUDSPERSONS

  Charlene Hubbell, BS, MT(ASCP), SBB
  Health Science Center
  Upstate Medical University
  HLA Laboratory
  750 E. Adams Street
  Syracuse, NY 13210
  Business Phone: 315/464-4775
  FAX Number: 315/464-9557
  Email:

  Vera Hauptfeld-Dolejsek, PhD, D(ABHI)
  University of Alabama at Birmingham
  West Pavilion P290
  619 19th Street South
  Birmingham, AL 35249
  Business Phone: 205/934-4987
  FAX Number: 205/975-6698
  Email:

  ---

  ADVISORY BOARD

  John Gerlach, PhD, D(ABHI)
  Michigan State University
  B228 Life Science Building
  East lansing, MI 48824
  Business Phone: 517/432-3467
  FAX Number: 517/353-5436
  Email:

  Walt Herczyk, MT(ASCP), CHS
  University of Chicago Medical Center
  Transplant Immunology Laboratory
  MC 0006 Rm: G-320
  5841 S. Maryland Ave
  Chicago, IL 60637
  Business Phone: 773/702-5388
  FAX Number: 773/702-2984
  Email:

   

  Doreen Jezek, MS, CHS
  University of Kentucky
  Immuno Molecular Pathology Laboratory
  800 Rose Street – Room HA629
  Lexington, KY 40536
  Business Phone: 859/257-4583
  FAX Number: 859/257-0029
  Email:

  ---

  Director Training Review Committee

  Angelo Arnold, PhD, HCLD
  Westchester Medical Center
  Tissue Typing Laboratory
  Grasslands Road
  Valhalla, NY 10595
  Phone 1: 914/493-6777
  Fax: 914/493-1104
  Email:

  ---

  Inspector Training

  Walt Herczyk, MT(ASCP), CHS
  University of Chicago Medical Center
  Transplant Immunology Laboratory
  MC 0006 Rm: G-320
  5841 S. Maryland Ave
  Chicago, IL 60637
  Business Phone: 773/702-5388
  FAX Number: 773/702-2984
  Email:

  ---

  STAFF

  Kathy Miranda
  Executive Director
  Association Headquarters
  15000 Commerce Parkway, Suite C
  Mt. Laurel, NJ 08054
  Business Phone: 856/439-0500
  FAX Number: 856/439-0525
  Email:

  Melissa Weeks
  Accreditation Manager
  SmithBucklin
  90 West County Road C, Suite 300
  St. Paul, MN 55117
  Business Phone: 651/487-2806
  FAX Number: 651/489-3387
  Email:

   

   

   

   

   

   

   

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  History

  Accreditation Program Background

  Mission, Purpose and Goal

  The mission is to promote quality practice in Histocompatibility and Immunogenetics through the objective and consistent evaluation of compliance with ASHI standards. The purpose of the accreditation program is to evaluate laboratory personnel, procedures and facilities to deter­mine if they are in compliance with those published standards of ASHI and with those standards of organizations by which ASHI is deemed and which apply to the activities of that laboratory. Laboratories will be evaluated for the technology utilized and, if applicable, the clinical services provided.

  The goals of the accreditation program are:

  1. To perform the evaluation process in an ethical, objective and timely fashion
  2. To promote the educational aspects of the accreditation process.
  3. To provide to various committees of the Society, data obtained in the accreditation process, which are useful for maintaining the Society's awareness of standard and novel procedures and methodologies.

  A Brief History of the Accreditation Program . . .

  With the objective of maintaining the highest standards of reliability and quality in histocompatibility testing laboratories, ASHI established its accreditation program in 1974. ASHI Accreditation was originally and still remains voluntary. Its purpose is to evaluate laboratory personnel, procedures, and facilities to determine if they are in compliance with ASHI standards; to promote the educational aspects of the accreditation process, particularly in assisting laboratories in the correction of deficiencies; to provide expert advice and assistance to committees of the society; and to maintain the society's awareness of standard and novel procedures and methodologies. Categories and techniques of accreditation include:

  Areas Of Accreditation

  HCS/BM Transplantation: Related Donor

  HCS/BM Transplantation: Unrelated Donor

  Solid Organ Transplantation: Deceased Donor

  Solid Organ Transplantation: Live Donor

  Parentage Testing

  Histocompatibility Testing for Other Clinical Purposes

  Transfusion Support

  Techniques

  Technologies	Methods
  Serology I	CDC
  Serology II	CDC
  DNA I	SSP, SSO, SBT
  DNA II	SSP, SSO, SBT
  Antibody Screening	CDC, ELISA, Flow, Microarray
  Antibody Identification	CDC, ELISA, Flow, Microarray
  Crossmatch	CDC, Flow, Microarray, Solid phase
  Engraftment / Fragment Analysis	SBT, STR, VNTR
  Cellular assays	MLC, Immune Monitoring
  Flow Cytometry	Immunophenotyping, CD34 Enumeration

  This voluntary program has accredited over 200 histocompatibility laboratories and is administered through the ASHI Accreditation Review Board. The Centers for Medicare and Medicaid (CMS), National Marrow Donor Program (NMDP), United Network for Organ Sharing (UNOS), The American Foundation for Donation and Transplantation (AFDT, formerly SEOPF) and the states of California, Florida, Oregon and Washington grant deemed status to ASHI accredited labs. The Joint Commission on Accreditation of Healthcare Organizations (JCAHO) recognizes ASHI Accreditation with Complimentary status. Any of these organizations may do their own inspections, however, for validation purposes or complaint response.

  Accreditation Program Historical Timeline

  ASHI Accreditation was originally and still remains voluntary.

  1974	Establishment of the Accreditation Committee
  1976	Start of Laboratory Evaluations
  1986	Upon recognition of the increasing diversity of histocompatibility testing and the growing number of laboratories seeking ASHI Accreditation, the ASHI Council charged the Accreditation Committee to revise the program to make it more specific to the activities of the laboratory
  1987	The reorganization program began in August 1986 and became effective in January 1987 Accreditation was granted or denied for specific laboratory activities Recognizing the need for a responsive program, which could perform a thorough and unbiased evaluation of histocompatibility laboratories performing testing for organ transplantation, UNOS contracted with ASHI to perform evaluation of laboratories applying for membership
  1988	ADTF (formerly SEOPF) adopted a policy of accepting ASHI Accreditation as a recognized approval of its member laboratories
  1990	The NMDP contracted with ASHI for laboratory evaluation services
  1992	NMDP began requiring ASHI Accreditation for its contract and transplant center laboratories
  1995	The ASHI Accreditation program achieved its deemed status with CMS (formerly HCFA) and CLIA
  1997	Deemed status with JCAHO, State of New York, Florida, Oregon and Washington.
  1998	New name given, Accreditation Program. New structure, Accreditation Board, and process defined.
  2004	ASHI Standards, Checklists, Guidelines, Inspection Packets, and Operations Manual updated.
  2005	CMS grants deemed status to ASHI as an accrediting organization for a period of 6 years, March 25, 2011
  2005	New ASHI Accreditation Program debuts, May 1, 2005 including a new online Interim Application and online Inspection’s Checklist
  2006	The ARB debuts the online On Site Application Packet
  2008	The ARB gains approval from CMS to accredit laboratories for General Immunology Testing subspecialty.
  2011	CMS grants deemed status to ASHI as an accrediting organization for a period of 5 years, through March, 2016 ASHI enters in to a cooperative agreement with The Joint Commission.

   

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  Frequently Asked Questions

    Is the ASHI PT program recognized by the College of American Pathologists (CAP)?

    ASHI is recognized by CAP as an alternative PT Provider.

    Is the ASHI Proficiency Testing Program approved by CMS (The Centers for Medicare and Medicaid services)?

    CMS currently has no requirement or provision for approving HLA typing and HLA antibody testing surveys.

    How do I order PT surveys?

    Order forms can be obtained from the ASHI central office (Cecilia’s attention) or from the ASHI website with some further instructions.

    How long do I have to report my proficiency testing results?

    The date by which results are due is listed on the Survey Schedule, available on the ASHI Web Site. Due dates are also shown on the instructions received with the survey kit.

    How are results submitted?

    Results are submitted directly via the internet.

    If my lab receives a Discrepant grade, are we required to submit a response to the ASHI PT Committee or Accreditation Review Board?

    The ARB requires that a laboratory evaluate the circumstances surrounding any Discrepant grades it receives, and take any necessary corrective actions.  The ARB reviews the laboratory’s follow-up to a Discrepant grade when the laboratory’s ASHI accreditation is up for renewal.  The ASHI PT Committee never requires a response from a laboratory about Discrepant grades, however, if a laboratory feels a Discrepant grade is unfair or incorrect, they should contact, by letter or e-mail, Cecilia Blair at the ASHI Central Office (see below).

    My lab is required to supply copies of the PT testing reports to the state.  Will that be handled as part of subscription, as in other PT programs, or will I need to do that myself?

    ASHI will forward testing reports to participant designated regulatory and other offices.  Please contact Cecilia Blair at the ASHI Central Office. (see below)

    What should I do if I did not receive my proficiency testing kit?

    Please contact Cecilia Blair at the ASHI Central Office. (see below)

    I noticed an error on our evaluation; will ASHI correct our evaluation?

    Whether an evaluation is corrected depends on the type of error. Participants need to contact the ASHI central office and the inquiry will be directed to the appropriate individual for review. If the error is due to your transcription error or failure to complete the result form appropriately, your entry cannot be reevaluated.

    What should I do if the results were submitted too late for evaluation?

    The ASHI Proficiency Testing Committee has decided that late submissions will be not be accepted or evaluated, except in extraordinary circumstances.  Any such requests need to be made to the ASHI central office.

    Who should I contact regarding questions, feedback, or ideas for the ASHI PT program?

    Please contact Cecilia Blair at the ASHI Central Office, (phone 1-856-642-4411 or email to )

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  PT Shipping Schedule

  Click here if the download does not automatically start.

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  CAP Release Form

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  PT Order Form

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  PT Brochure

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  Operations Manual

  The operation and activities of the Accreditation Review Board are reviewed at several levels. These include ASHI Board of Directors and CMS. Because of the deemed status agreements with CMS, NMDP and UNOS, procedures and policies of the ARB must be submitted for review and approval. As a result a detailed Operations Manual was created to provide a single source document for all activities of the ARB. A copy is available by clicking on the link below. Questions and clarifications pertaining to this manual may be addressed to Melissa (McElroy) Weeks, ASHI Accreditation Manager.

  Accreditation Program Operations Manual (Adobe PDF)

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  Forms and Documentation

  Please click on the links above to access the appropriate forms.

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  Get Accredited

  Get Accredited! Learn how!

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  Accreditation

  Welcome to ASHI's Accreditation Program. Please click on the links above to access accreditation information and files.

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  Proficiency Testing Program

  

  ASHI is pleased to announce the 10th year of its comprehensive proficiency testing program.

  • Our program utilizes clinically-based samples to assess a laboratory’s ability to accurately perform its analyses. Specimens are characterized by recognized experts in histocompatibility testing with oversight by ASHI’s Proficiency Testing Committee.
  • Current survey categories, designed to emulate routine clinical testing, will be maintained: HLA Typing (Class I & II in the same survey), HLA-B27 Detection, Engraftment Monitoring, and Antibody Screening/Identification and Crossmatching.      
  • To further emulate clinical testing, Class I & II antibody tests and T & B cell crossmatching are reported using the same serum and cell samples. In addition, whole blood samples are provided for both typing and crossmatching tests.
  • Modular configuration of the surveys provides flexibility and cost savings. Additional cost savings are possible with the new 2012 Typing Survey configuration.  
  • Surveys continue to feature a user-friendly data submission Web site for easy results entry.
  • Summary Reports and concurrent individual Performance Reports present data in a concise and informative fashion, with emphasis on the educational goals of the ASHI Proficiency Testing Program.
  • As always, the program is designed to fully meet the latest ASHI standards for laboratory accreditation.
  • ASHI is accepted by the College of American Pathologists (CAP) as an alternative proficiency testing program provider for the HLA Typing, HLA-B27 Detection, and Antibody Screening/Identification and Crossmatching surveys. If your laboratory is accredited by CAP, ASHI is able to report your ASHI PT Survey Performance Reports directly to CAP.
  • ASHI-accredited laboratories may choose to have their ASHI PT Survey Reports sent directly to the ASHI Accreditation Review Board (ARB).

  If you are a new lab and have not registered before, please contact Cecilia Blair at the ASHI central office at .

  Click here to place your 2012 PT Order, to enter results for 2012 Surveys or to view your laboratory’s previous Performance Reports and Summary Reports for surveys that have been completed.

   

  ---

   

  SURVEY: 2012 AC-1

  Region A

  Specimen AC-045:  A2, 74; B35, 53; Cw4, w6; DR13, 15; DR51, 52; DQ6; DQA1*01:02; DPB1*01:01, 105:01  
  Specimen AC-046:   A33; B53; Cw4; DR13, 18; DR52; DQ4, 5; DQA1*01:02, 04:01; DPB1*01:01, 17:01

   

  Region B

  Specimen AC-047:  A2, 66; B8, 52; Cw7, C*16; DR13; DR52; DQ5, 6; DQA1*01:03; DPB1*01:01, 17:01/131:01 
  Specimen AC-048:  A2, 30; B18, 71; Cw2, w3; DR7, 11; DR52, 53; DQ2, 7; DQA1*02:01, 05:05/05:09; DPB1*01:01, 17:01/131:01

  
  

  Region C

  Specimen AC-049:  A2, 30; B27, 35; Cw2, w4; DR11, 13; DR52; DQ6, 7; DQA1*01:03, 05:01:01G; DPB1*01:01, 04:01  
  Specimen AC-050:  A23, 74; B7, 72; Cw2, w4; DR13, 14; DR52; DQ5, 6; DQA1*01:02, 01:04; DPB1*02:01

   

   

  SURVEY: 2012 HT-1

  Region B
  HT-121, HT-122, HT-123, HT-124, HT-125 - African American

  Region C
  HT-126, HT-127, HT-128, HT-129, HT-130 - African American

   

  SURVEY: 2011 AC-2
  CORRECTED TYPINGS 11/2/2011

  Region A
  Specimen AC-039: A29, 33; B53, 65; Cw4, w8; DR1, 8; DQ5, 7; DQA1*01:01, 04:01; DPB1*01:01, 17:01
  Specimen AC-040: A2, 3; B44, 51; Cw1, w7; DR1, 13; DR52; DQ5, 6; DQA1*01:02; DPB1*02:01

  Region B
  Specimen AC-041: A2; B8, 44 (not 44:03); Cw5, w7; DR15, 17; DR51; DR52; DQ2, 6; DQA1*01:02, 05:01; DPB1*04:01/126
  Specimen AC-042: A2, 32; B7, 27; Cw2, w7; DR12, 15; DR51; DR52; DQ6, 7; DQA1*01:02, 05:05/09; DPB1*03:01/104/124, 04:01/126
                         
  Region C
  Specimen AC-043: A1; B8, 27; Cw1, w7; DR4, 11; DR52; DR53; DQ7, 8; DQA1*03:01, 05:05; DPB1*03:01
  Specimen AC-044: A2, 68; B35, 53; Cw1, w4; DR9, 15; DR53; DQ2, 6; DQA1*01:02, 03:03; DPB1*01:01

  SURVEY: 2011 HT-3

  Region B
  HT-111, HT-112, HT-113, HT-114 – African American
  HT-115 –Caucasian
  
  Region C
  HT-116, HT-117, HT-118, HT-119, HT-120 – African American

  SURVEY: 2011 HT-2
  
  Region B
  HT-101, HT-103, HT-104 – African American
  HT-102, HT-105 –Caucasian
  
  Region C
  HT-106, HT-107 – African American
  HT-108, HT-109, HT-110 - Caucasian

  SURVEY: 2011 AC-1

  Region A
  AC-033: A1,2; B51,57; Cw1,w6; DR7,11; DR52; DR53*; DQ7,9; DQA1*02:01,*05:05; DPB1”04:01,*04:02
  AC-034:  A3,69; B35,63; Cw4,w7; DR1,11; DR52; DQ5,7; DQA1*01:01,*05:05; DPB1*04:01
  
  Region B
  AC-035:  A24, 33; B41,72; Cw6,*17; DR11,13; DR52; DQ6; DQA1*01:02; DPB1*02:01,*04:01
  AC-036:  A2,3; B44,47; Cw5,w6; DR4; DR53; DQ7,8; DQA1*03:01,*03:03; DPB1*04:01,*06:01
  
  Region C
  AC-037  A2,30; B42, 72; Cw2,*17; DR17,18; DR52; DQ2,4; DQA1*04:01,*05:01; DPB1*01:01
  AC-038  A1,2; B8,57; Cw6,w7; DR7,17; DR52; DR53*; DQ2,9; DQA1*02:01,*05:01; DPB1*02:01,*04:01/126:01
  
  * DR53 was assigned to these cells by low resolution molecular typing but is likely to be a “null” allele in both cases, based on known linkage disequilibrium with B57, DR7 and DQ9

  SURVEY: 2011 HT-1

  Region B
  HT-091, HT-092, HT-094, HT-095 – African American
  HT-093 – Caucasian
  
  Region C
  HT-096, HT-097, HT-098, HT-099, HT-100 - African American

   

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  ASHI Lab Center

  Welcome to the ASHI Lab Center…home for all the information that matters to your laboratory!  Click the links above to access information regarding ASHI’s Accreditation or Proficiency Testing Program.

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  New Login Procedure

  Member Restricted Access

  If you are like most people who use the internet, you probably have a multitude of usernames and passwords to remember. There is information on the ASHI web site that is restricted to viewing by ASHI members only () and, up to this point, the password has changed with every new issue of ASHI Quarterly. From now on, you will only need to remember two things to access these areas.

  Your first initial and last name is now your username, and the password is your 5-digit Membership ID Number. Both your name and your Membership ID number are indicated on the membership card issued to each member beginning with the current membership year. For example, if your name were John Jones and your Membership ID Number 00000, when clicking on a page restricted to viewing by members only, you would enter “JJones” as your username, and “00000” as your password (without quotes).

  Once you have logged in, you will not have to log in again for any member-restricted area during your visit to the site. In order for this to work, you must enable the use of "cookies" on your computer. In this case, the "cookie" is a small piece of information stored in memory (nothing is written to your hard disk) that tells our web site you have successfully logged in. The "cookie" is removed when you leave. The same login mechanism will also allow you to edit and update your membership directory information on line. Parts of ASHI Digital Discussions area will still require a separate password, but you could change your password to your Membership ID Number to keep it consistent across the web site.

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  Update Your Profile

  Use the form below up update your information on record with the ASHI national office.  An ASHI representative may contact you to confirm details.

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  For Patients

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  For general information: ASHI Executive Office 15000 Commerce Parkway, Suite C Mt. Laurel, NJ 08054 Phone: 856-638-0428 Fax: 856-439-0525 Get connected with social media, click here.
  Executive Director	Kathy Miranda (856) 793-0907
  Assistant Executive Director	Leslie Clark (856) 380-6861
  Accreditation	Melissa (McElroy) Weeks Accreditation Manager (651) 487-2806  (651) 489-3387 fax
  Meetings	Nadege Toth Meeting Manager (856) 793-0766 Craig Solomon Meeting Coordinator (856) 380-6806
  Membership/Proficiency Testing	Cecilia Blair Membership Services Coordinator (856) 642-4411
  Communications	Frank Scussa Managing Editor, ASHI Quarterly (856) 642-4427

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  Home > In Memorium

  In Memorium

  We celebrate the memory of members who are no longer with us. Your contributions to these pages are always welcome.

  
  

  ---

  
  

  Jean Dausset, MD was a French immunologist.  He received the Nobel Prize in Physiology or Medicine in 1980 along with Baruj Benacerraf and George Davis Snell for their discovery and characterization of the genes making the major histocompatibility complex. With his Nobel Prize and a grant from the French Television, Dausset was able in 1984 to create the Human Polymorphism Study Center (CEPH). 
  

  Jean Dausset passed away on Saturday, June 6th 2009 at the age of 92 in Mallorca, Spain.  We will remember him as a giant and a visionary as well as a dedicated humanist.

  
  

  http://en.wikipedia.org/wiki/Jean_Dausset

  
  
  

  
  

  ---

  
  Yehia Awadalla, M.D., Ph.D.

  Yehia Awadalla, M.D., Ph.D. passed away on July 9, 2008, at the age of 58. He was Professor of Microbiology and Immunology at Ain Shams University School of Medicine in Cairo, Egypt. He served as Director of the Tissue Typing Laboratories at King Fahad Hospital Saudi Arabia, and at Ain Shams University Medical Center.

  In 2001, Dr. Awadalla joined the Tissue Typing Laboratories at the University of Pittsburgh Medical Center as a visiting professor. His research in Histocompatibility dealt with the structural basis of HLA matching, antibody reactivity with HLA epitopes, and the role of HLA in BK virus nephropathy in kidney transplant recipients. He has presented his data at ASHI Meetings and other HLA meetings, and he authored several peer-reviewed publications. Dr. Awadalla was a member of ASHI, and he became an ASHI-certified laboratory director.

  Yehia received a liver transplant in 1994. Unfortunately, he experienced many medical complications that lead to his untimely death. He is survived by his wife, Gigi, and three teenaged children. We at the UPMC Tissue Typing Laboratories will miss our dear friend and colleague.

  René Duquesnoy, Ph.D.

  
  

  ---

  
  

  Norman C. Kramer
  Physician, Kidney Specialist

  Norman Clifford Kramer, 78, a kidney specialist who became an emeritus professor of medicine at George Washington University Medical Center,
  died Oct. 11 at the center. He had complications from pneumonia.

  Dr. Kramer, a Washington resident, spent more than 20 years on the center’s staff before retiring in 1985. Besides his teaching duties, he was involved in clinical studies of organ donation for kidney transplants.

  He was the founding director of GWU’s histocompatibility and immunogenetics laboratory, which aided the medical center’s transplant program. During his career, he also was co-director of D.C. General Hospital’s renal clinic.

  After his retirement, he was director of laboratories at the Maryland Medical Laboratory Inc. in Halethorpe, Md.; what is now the Lehigh Valley Hospital and Health Network in Allentown, Pa.; and the University of Puerto Rico in San Juan.

  Since 1999, he had been director of Howard University Hospital’s histocompatibility and immunogenetics laboratory.

  He was a native of the Bronx, N.Y., and a chemistry and physics graduate of the Citadel in South Carolina. He received a master’s degree in biochemistry from GWU, where he was also a 1954 graduate of the medical school.

  After three years in the Air Force, he did his residency at D.C. General and had a renal fellowship at GWU.

  He was a former board member of several medical societies and associations, including the Southeastern Organ Procurement Foundation.

  He retired from the Air Force Reserve as a captain in 1972.

  Survivors include his wife of 52 years, Patricia Elly Kramer of Washington; five children, Mary Virginia Custer of Burtonsville, John Kramer of Rockville, Bernard Kramer of Silver Spring, Peter Kramer of Arlington and Anne DiMarco of Adamstown, Md.; and 12 grandchildren.

  
  

  ---

  
  

  Charles G. Orosz
  WALKING WITH GIANTS

  I have suspected it often and for a long time. Now, I’m sure: I walked and talked and worked with a giant.

  On August 23, 2005, we feted the life and accomplishments of Charles G. Orosz, affectionately known to everyone as “Charley,” at a memorial gathering held at the Ohio State University Medical Center. The speakers were a diverse group of 15 individuals, including a dean, distinguished immunologists, PhDs and MDs Charley had mentored, ASHI’s immediate past president, and Charley’s local “lieutenants,” which included me. What struck me most was how we all, from diverse perspectives and experiences, sounded the same broad themes that underpinned his remarkable life.

   

  DISTINGUISHED SCIENTIST AND IMMUNOLOGIST
  Charley will be recognized as ASHI’s 2005 Distinguished Scientist in Washington at the annual meeting. His development of experimental approaches to understand cellular interactions involved in graft acceptance/rejection are recognized throughout the world.

  PRODIGIOUS AUTHOR
  Charley’s research on the immunobiology of graft acceptance was supported for many years by the National Institutes of Health. He authored more than 200 peer-reviewed publications and received many honors and awards. In addition, he was associate editor for the Journal of Immunology and served on the editorial boards of seven international journals.

  MENTOR
  Charley mentored a variety of individuals at many different levels. He helped forge the professions of individuals seeking post-graduate training in transplantation immunobiology, careers in academic medicine, and clinical histocompatibility testing at both the technologist and director level. His mentoring continued well after the termination of someone’s formal training.

  COLLABORATOR
  Whether it was a program project, meeting organizer, or the ASHI board of directors, Charley was skilled at ferreting out the very best that every player brought to the table. He coordinated everyone’s talents to work to greatest advantage on the project at hand.

  DEDICATION TO EXCELLENCE
  Whatever Charley undertook, the goal was to execute with excellence. If it was worth doing, it was done very well. This dedication to excellence was fueled by boundless energy and an enthusiasm that was infectious.

  MISCHIEVOUS MAVERICK
  With a glint in his eye, mirrored by the grin on his face, Charley might give vent to the rebel in his spirit. The challenge was never meant to harm, but it often threatened the status quo and always with good purpose. Those who were fortunate to work closely with Charley quickly discovered that he thought out-of-the-box. This thinking brought new ways to approach old problems. He was uniquely gifted to take ASHI’s new structure and put it to the test. He was confident and comforted to know that, despite the interruption of his active presidency since late December 2004, ASHI was still moving forward.

  HAPPY FEET
  At the end of the day, after all the committee work, workshops, and sessions it was time for those tired, but happy feet. Charley worked hard and played hard. Who can recall an ASHI meeting without Charley’s frenzy on the dance floor coming to mind? I last saw Charley dance at his son’s wedding this past June. Although Charley was in attendance in a wheel chair, due to a painful leg infection, he got out of his chair when it came time to dance. Those happy feet demanded their moment.

  FRIEND
  No matter the context, Charley forged friendships and naturally perforated the line separating professional and personal lives. He was easy to get to know, and eagerly shared his expertise and life experiences with many stories and a broad smile stretching beneath his hallmark mustache.

  CHARLEY’S CHALLENGE
  Charley last addressed our membership at the annual meeting held in San Antonio on October 5, 2004. He presented his vision as our incoming president during this address. He said, “We are now entering the young adulthood of ASHI, which is characterized by an altruistic citizenship, an interest in taking our place as a recognized, contributing member of the transplant community. This period is marked by an emergence from the self interests of our adolescence, and the adoption of a clear, outward focus on the interest and needs of the various components of the transplant community.” He ends, “In short, we need to let people know that we are ready, willing and able to help them.” These words reflect the passionate commitment to excellence and service that were hallmark characteristics of Charley Orosz. They can be summarized as: We’re ASHI, and we’re here to help. That’s the challenge Charley gave us as we left the meeting and went back to our home labs and local programs.

  THE MEASURE OF THE MAN
  Following their death, a very select group of individuals become larger than life. These are the heroes that we draw on for inspiration. Once in a very great while, someone comes along who is larger than life while they are with us. Charley Orosz was one of these rare giants.

  Ed. Note: Charles G. Orosz passed away Sunday, August 7, 2005. He had been ill for the past eight months.

  Article contributed by:
  Patrick Adams, CHS

  
  

  ---

  
  

  J. Roberto Moraes, MD, PhD
  (1944-2005)

  The loss of a dear friend
  We have said good-bye to a friend, almost a member of our family. Jose Roberto Moraes came to Dallas the first time in 1973: that is 32 years ago. When he first came to us, he stayed in our home. He played soccer with our kids. We loved him dearly and will miss him forever and so will many others who were touched by his gentle character, his friendly smile, his behavior of gentleman and scholar.

  A model student and a hard worker
  Having finished his residency in internal medicine just about when his hospital in Rio decided to start a kidney transplant program, Roberto Moraes was asked to set up the Histocompatibility Laboratory. And so he came to learn typing, screening and crossmatching in our lab. He was dedicated and hard working and tireless in his pursuit of new knowledge.

  Many happy returns to the mentor’s lab: 1973, 1975-1977, 1988-1991
  Having quickly learned the basics and after the transplant program in Rio became a reality, Roberto came back on two occasions to do research. In 1975, he was joined by his wife Maria Elisa and they both worked on related problems for two years. Roberto started his life-long interest in endothelial cell antigens and published key papers. In 1988, they came again. This time they remained for three years. The family then included three daughters.

  Alloantigens other than HLA expressed in endothelial cells and their probable role in transplant rejection
  The main topic of Roberto’s research was the investigation of antibodies against alloantigens distinct from HLA, expressed in endothelial cells and not in lymphocytes. He rapidly obtained results and the first paper appeared already in 1975. These polymorphic antigens were later found also in monocytes and in keratinocytes. Through hard work and perseverance it was established that such antibodies were correlated with early humoral rejection of kidney allografts.

  Brazilian Society for Histocompatibility and Immunogenetics (1979); Latino-American Histocompatibility Society (1981); International Histocompatibility Workshops.
  Roberto was active in forming a Brazilian Histocompatibility Society and together with others, particularly Zulay Layrisse of Venezuela , founded the Latino-American Histocompatibility Society. He also participated in the International Histocompatibility Workshops and was highly regarded by members of the international community.

  Bone Marrow Transplant Center (CEMO, 1984) and Solid Organ Transplant Center (PITO, 1986) in Rio ; Database of Unrelated Bone Marrow Donors in Sao Paulo , started in 1993
  In subsequent years, much of Roberto’s effort went to the establishment of immunogenetic support for bone marrow transplantation in Rio de Janeiro and in Sao Paulo . He also facilitated and coordinated the distribution of donor kidneys for transplant centers in five participating hospitals.

  Brazilian Bone Marrow Registry in Rio (1998)
  After he visited the American National Marrow Donor Program (NMDP) these efforts culminated in the development of a Brazilian Marrow Donor Registry, first in Sao Paulo and subsequently, on a much larger scale, in Rio de Janeiro.

  A legacy and a memory
  This kind man, taken away prematurely from his family and friends, will be remembered always by his colleagues. He was liked by everyone, he was trusted and he was admired for his integrity and his contributions to our community. Farewell Roberto. We will miss you

  Article contributed by:
  Peter Stastny, MD
  Transplantation Immunology Division
  Department of Internal Medicine
  UT Southwestern Medical Center

   

  
  

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  • ASHI Quarterly (3rd Qtr 2002) (*.pdf, 64KB)
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  ASHI News Room

  The American Society for Histocompatibility and Immunogenetics (ASHI) is a not-for-profit association of clinical and research professionals including immunologists, geneticists, molecular biologists, transplant physicians and surgeons, pathologists and technologists. As a professional society involved in histocompatibility, immunogenetics and transplantation, ASHI is dedicated to advancing the science and application of histocompatibility and immunogenetics; providing a forum for the exchange of information; and advocating the highest standards of laboratory testing in the interest of optimal patient care.  If you would like to receive ASHI press releases regularly via email, please subscribe by writing to .

  Media Contact: Communications Manager

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  Corporate Support

  By becoming an ASHI Corporate Supporter, your organization will benefit by contributing to ASHI's educational programs.  This is your chance to increase exposure to leading professionals, ASHI members, and non-members from all types of organizations and institutions, and the histocompatibility and immunogenetics community worldwide. ASHI offers a variety of support levels to fit your organization's interest, budget and marketing goals.  We can help you identify the sponsorship level that best fits your needs and makes the most of your support contributions!

  Questions?  Please contact ASHI Headquarters at or 856-638-0428.

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  Join ASHI

  The American Society for Histocompatibility and Immunogenetics (ASHI) is a not-for-profit association of clinical and research professionals including immunologists, geneticists, molecular biologists, transplant physicians and surgeons, pathologists and technologists.  As a professional society involved in histocompatibility, immunogenetics and transplantation, ASHI is dedicated to advancing the science and application of histocompatibility and immunogenetics; providing a forum for the exchange of information; and advocating the highest standards of laboratory testing in the interest of optimal patient care.

  To print and download membership application form, click here.

  To begin the online application, please select the button below.

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  Home > HLA 1998

  HLA 1998

  Published by: American Society for Histocompatibility & Immunogenetics
  Edited by: David W. Gjertson, PhD and Paul I. Tersasaki, PhD

  Click here for Table of Contents

  HLA 1998 was produced to provide the HLA community with the latest information on the frequencies of HLA alleles and goes hand in hand with HLA 1997 which included mainly Class II data. In HLA 1998, much more Class I data is included. This timeless reference text contains summary tables, together with world maps on HLA-A, -B and –DP allele frequencies and provides an idea of how alleles are distributed in different populations. Tables of 2-locus haplotype frequencies for A/B and DRB1/DQB1 alleles were generated across four ethnic groups (Asians, Blacks, European and North American Caucasians) formed by combining appropriate studies. Chapter 4 includes a particularly useful table that lists the two hundred most common HLA-A,-B,-DR haplotypes with their estimated frequencies and ranking within five different racial groups.

  If you are interested in purchasing a copy of HLA 1998, please complete and return your order form to the ASHI Central Office by email () or fax (856-439-0525).

  HLA 1998 Order Form

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  Suggested Study Materials

  As a certifying agency, ABHI is not directly involved in assisting individuals to prepare for examinations. Applicants may wish to consult some of the following sources for background and specific information in the various content areas to be covered by the CHA, CHT, CHS, or Histocompatibility Laboratory Director examinations. Alternate materials are also available in most medical libraries.

  
  

  Content Areas

  
  

  • ABHI Statements of Competence for Histocompatibility Personnel, 1998
  • ASHI Standards for Histocompatibility Testing, 2006
  • UNOS Standards for Histocompatibility, 2005
  • ASHI Laboratory Accreditation Inspection Checklist, 2006
  • CAP Laboratory General Checklist, 2005
  • CAP Histocompatibility Checklist, 2005, 2007

  
  

  General Laboratory Skills and Safety

  
  

  • OSHA Guidelines, Federal Register, 56 (No235): pp 64175-64182, 1991
  • CMS CLIA Regulations, Federal Register, 68 (No16): pp 3639-3714, 2003
  • Laboratory Safety: Principles and Practices (1995) Am Society Micro, Washington, DC
  • ASHI Laboratory Manual, 4th Ed. 2001, updates 2005

  
  

  Laboratory Management

  
  

  • Clinical Laboratory Medicine, K. McClatchey (ed), Lippincott, Williams & Wilkins, 200
  • Management: Theory, Process and Practice, RM Hodgetts
  • Clinical Laboratory Management Review. Bi-monthly from CLMA, Williams & Wilkins

  
  

  Basic Immunology

  
  

  • Cellular and Molecular Immunology, 5th Ed. A. Abbas (ed). Saunders 2005
  • Essential Immunology, 6th Ed. Roitt, Brostoff & Male. Mosby 2001
  • Immunology: The Immune System in Health and Disease, 6th Ed. C. Janeway (ed) Garland Publishing, 2004
  • Microbiology and Immunology Online - University of South Carolina School of Medicine
  • The Immune System, P. Parham, Garland Publishing, Elsevier Science, 2004
  • Illustrated Dictionary of Immunology, JM Cruse & RE Lewis. CRC Press, 2002

  
  

  Histocompatibility and Immunogenetics

  
  

  • Clinimmune Practice Exam 
  • HLA Facts Book, Marsh, Parham,& Barber, Academic Press, 2005
  • HLA in Health and Disease 2nd Ed., Academic Press, 2000
  • HLA Beyond Tears, 2nd Ed. GE Rodey DeNovo, Inc. 2000
  • The HLA Dictionary 2004, Schreuder, Hurley, Marsh,etal: Tissue Antigens (2005) 65,1-55;
    or Human Immunology (2005) 66,170-210; or International Journal of Immunogenetics (2005) 32,19-69.

  
  

  Transplantation

  
  

  • Primer on Transplantation, 2nd Ed. Norman & Suki, AST, 2001
  • Clinical Transplants, published yearly 1988-present, Cecka & Terasaki, (eds) UCLA Tissue Typing Laboratory, Los Angeles, CA
  • Hemopoietic Cell Transplantation, 3rd Ed. Thomas, Blume & Forman, Blackwell Science
  • Cord Blood Characteristics: Role in Stem Cell Transplantation, Cohen, Gluckman, Rubinstein & Madrigal (eds). Blackwell Science, Inc. 2000

  
  

  Flow Cytometry

  
  

  • Immunophenotyping, Stewart & Nicholson (eds) Wiley-Liss, Inc, 2000
  • Flow cytometry in Clinical Diagnosis, Keren (ed) ASCP Press 3rd Ed, 2001
  • Practical Flow Cytometry, 4th Ed. Shapiro (ed) Wiley-Liss, Inc. 2003

  
  

  Molecular Biology

  
  

  • DNA Methods for HLA Typing – Workbook
  • DNA Methods for HLA Typing – Answers
  • DNA: The Secret of Life, Barry & Watson, Knopf Publishing, 2003.
  • Genes VIII, Lewin, 8th Ed, Wiley & Sons, 2003.
  • PCR Technology: Current Innovations, Library of Congress, Cataloging-in-Publication Data, 2nd Ed, 2003.
  • Molecular Biology of the Cell, 4th Ed. Alberts, Garland Publishing, 2002.
  • Human Molecular Genetics, 3rd Ed. Strachan, AP Read, 2003.
  • Molecular Typing 2000: A Technical Manual for Histocompatibility Laboratories, AFDT or American Foundation for Donation and Transplantation

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  2011 Corporate Supporters

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  ASHI Quarterly

  The ASHI Quarterly is a newsletter published to communicate information to the membership regarding Society activities, and clinically-relevant scientific articles of interest to the histocompatibility and immunogenetics community. Issues addressed include updates on the activities of the Accreditation Program, new governmental regulations, summaries of the annual meeting and regional workshops, new product updates and literature reviews. An ASHI Quarterly subscription is included as a membership benefit to all full, associate, institutional and sustaining members.

  Access to articles printed in the ASHI Quarterly is available to ASHI members on the Members Only site

   

   

   

  For information on placing an advertisement in the ASHI Quarterly, please contact Kathy Miranda at or 856-793-0907.

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  Human Immunology

  Human Immunology is a monthly, peer-reviewed journal providing an exchange of information and ideas on structural polymorphism of HLA genes in healthy and diseased populations, their function, regulation and expression in normal and malignant cells. The journal also publishes research on the structure and function of molecules that play a role in the activation and regulation of the immune system, and on the immune response of patients with transplants, autoimmunity or infectious diseases. Subdisciplines such as neuroimmunology, immunopharmacology, and developmental and reproductive immunology are included, as well as editorials and seminar series on topics of general concern.

  Human Immunology is published 12 times a year by Elsevier Science Publishing Company, New York. A subscription is included in ASHI full, sustaining full, institutional and sustaining institutional membership categories. Click here for an order form for members (pdf).

  Abstracts and full length text of papers published in our scientific journal, Human Immunology , are available on the Elsevier web site. Follow the path below for first time registration.

  Online access to full text articles is free to all ASHI Members. Please click here (first time registration ) to sign up for the first time.

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  Sample Questions

  CHT/CHS Questions

  The CHT and CHS Examinations have been developed to objectively measure the knowledge and skills required for histocompatibility technologists and specialists. Both examinations contain 150 multiple-choice questions. The examinations are developed by an examination committee of experts in the field who are appointed by ABHI.

  The following are examples of multiple-choice questions. Each of the questions is followed by four suggested answers. Select the one answer that is the best for each question. Click on following question numbers to start:

  
  CHT/CHS Question 1
  CHT/CHS Question 2
  CHT/CHS Question 3
  CHT/CHS Question 4

   

  Director Exam Questions

  The Histocompatibility Laboratory Director Examination has been developed to objectively measure the knowledge and skills required for serving as the director of a histocompatibility laboratory. The examination contains 200 scored multiple-choice questions and is divided into two parts. Part 1 contains 110 scored items to be administered in 3 hours, and part 2 contains 90 scored items to be administered in 2 hours. Thirty additional pretest (not scored) items are interspersed to each part of the exam (15 to Part 1 and 15 to Part 2). A detailed content outline can be found in the candidate handbook. The examination is developed by a committee of experts in the field who are appointed by ABHI.

  The following are examples of multiple-choice questions. Each of the questions is followed by four suggested answers. Select the one answer that is the best for each question. Click on following question numbers to start:

  
  Director Exam Question 1
  Director Exam Question 2
  Director Exam Question 3
  Director Exam Question 4
  Director Exam Question 5
  Director Exam Question 6
  Director Exam Question 7
  Director Exam Question 8
  Director Exam Question 9
  Director Exam Question 10
  Director Exam Question 11
  Director Exam Question 12
  Director Exam Question 13
  Director Exam Question 14
  Director Exam Question 15
  Director Exam Question 16
  Director Exam Question 17
  Director Exam Question 18
  Director Exam Question 19
  Director Exam Question 20

  American Society for Histocompatibility and Immunogenetics

  

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  Home > Abstracts

  Abstracts

  Please wait while we take you to the ASHI Abstracts system. If you are not automatically redirected continue to the ASHI Abstracts system.

  American Society for Histocompatibility and Immunogenetics

  

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  Home > Accepted CE Activities

  Accepted CE Activities

  The following are acceptable as CE activities:

  1. Programs approved by the American Board of Histocompatibility and Immunogenetics (ABHI). This includes ASHI national and regional programs or any other programs sponsored by other organizations that have applied to ABHI for approval. These programs must be at least one (1) hour in duration and be a formally organized scientific or career-related education, plenary or poster session, workshop,roundtable, symposia or coloquia whose content covers at least one of the major fields of competence of the ABHI "Statements of Competency for Histocompatibility Personnel." Credit will be calculated at the rate of 0.15 CEC per contact hour . Documentation of attendance must be submitted to ABHI for credit.
  
  
  2. Programs which meet the above criteria but are not ABHI approved may be submitted for CE credit. However, credit will be calculated at the rate of 0.1 CEC per contact hour . Documentation of attendance must be submitted to ABHI for credit.
  
  
  3. Earned academic credit in career-related college or university course work calculated at the rate of 1 semester hour = 1.5 CEC's and 1 quarter hour = 1.2 CEC's. Course descriptions and official transcripts of successful completion of academic course work are required for credit. A maximum of 4.5 CEC's may be claimed per three (3) year period.
  
  
  4. Presentation of a paper, poster or workshop at any meeting or workshop pertaining to the field of histocompatibility and immunogenetics. Maximum credit for each presentation is 0.3 CEC. Additionally, a maximum of 1 CEC may be claimed for the time spent on the preparation of the presentation. A copy of the program or other appropriate documentation is required for credit.
  
  
  5. Performance of laboratory work or analysis for, but not actual attendance or presentation of, data at any national or international histocompatibility workshop. Signature of the laboratory director, supervisor or sponsor will be required as verification of participation to receive credit. Credit will be calculated at the rate of 0.1 CEC per contact hour. A maximum of 1 CEC may be claimed per three (3) year period.
  
  
  6. Be listed as an author, within your 3 year cycle, of a paper or chapter in a recognized journal or book pertaining to histocompatibility and/or immunogenetics. A maximum of 1 CEC may be claimed for each chapter or publication and appropriate documentation (e.g., copy of abstract, etc.) is required for credit.
  7. 
     Teaching of histocompatibility and immunogenetics or career-related subjects to allied health professionals, quality control managers, histocompatibility and immunogenetics students, medical students and residents, nurses, and other health professionals. Credit is awarded at the rate of 0.1 CEC per contact hour with a maximum of 1.5 CEC per three (3) year period. Signature of the laboratory director, supervisor or sponsor will be required as verification of participation to receive credit.
  
  
  8. The performance of an on-site laboratory inspection for the ASHI laboratory inspection program. A maximum of 0.8 CEC may be claimed per inspection with a maximum of eight (8) inspections per three (3) year period. Documentation from ASHI is required for credit.
  
  
  9. The time spent serving as a committee member of ASHI , ABHI or other prorofessional organizations or associations (e.g., SEOPF , UNOS ) relating to histocompatibility and immunogenetics. A maximum of 1 CEC per year may be claimed for each committee membership in addition to 2 CEC's per year for committee chairs. Documentation is required for credit.
  
  
  10. Attendance at an ABHI approved audio/visual recorded presentation of any ASHI scientific meeting or other symposia of career-related material. Signature of the laboratory director, supervisor or sponsor will be required as verification of participation to receive credit. Credit will be awarded at the rate of 0.15 CEC per contact hour with a maximum of 1 CEC per three (3) year period.
  
  
  11. Self-instruction of career related topics can be claimed at the rate of 0.1 CEC per contact hour for the following:
      (1) Any audio/visual materials.
      (2) Open or closed circuit television and radio broadcasts and instruction using telephone networks (i.e., teleconferences).
      (3) Reading of publications on histocompatibility and immunogenetics and other related medical literature.
      
      Signature of the laboratory director, supervisor or sponsor is required for credit. A maximum of 1 CEC may be claimed per three (3) year period.
  12. Programs which include the areas of safety, management, computer technology and quality assurance may be submitted for CE credit. Credit will be calculated at the rate of 0.1 CEC per contact hour. Documentation of attendance must be submitted to ABHI for credit. A maximum of 1.5 CEC may be claimed per three (3) year period.

  In-house Continuing Education Program An excellent way for histocompatibility labs to provide continuing education credits for their technologists is to plan and execute an in-house continuing education program. The process and application are fully described below. Labs can hold monthly journal clubs or invite speakers to talk about one of the many areas that fall within the "Statements of Competence for Histocompatibility Personnel". Preferably, the program is planned at the beginning of the year and the application is completed for the entire year or an application may be filled out for each session to be held. The session must be at least 1 hour in length and attendance must be taken. The program must be sponsored by the lab that is submitting the application.

   

  ---

  Application Form For Continuing Certification (89KB, PDF)

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  Home > International Summer School

  International Summer School

  The 9th International Summer School on Immunogenetics -
  
  

  This year’s meeting is being organized by APHIA (Asia-Pacific Histocompatibility and Immunogenetics Association) with support from ASHI (American Society for Histocompatibility and Immunogenetics) and EFI (the European Federation for Immunogenetics). The meeting will be held at the Whaler’s Inn Resort, Victor Harborm South Australia from the 11th - 13th November 2012. 

  For more details, click here.

  Application Deadline TBD

  
  

  ---

  
  

  Historical Information
  

  The following information regarding past International Summer School on Immunogenetics is available for historical purposes.

  The 8th International Summer School on Immunogenetics -2011

  The 7th International Summer School on Immunogenetics -2010

  The 6th International Summer School on Immunogenetics -2009

  The 5th International Summer School on Immunogenetics -2008

  The 4th International Summer School on Immunogenetics -2007

  The 3rd International Summer School on Immunogenetics -2006

  The 2nd International Summer School on Immunogenetics -2005

   

  American Society for Histocompatibility and Immunogenetics

  

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  Home > Exam Matrices

  Exam Matrices

  To begin your preparation in an informed and organized manner, you should know what to expect from the actual examination in terms of the content tested. The test matrices describe the content categories covered on the examination. The matrices can be used to get a general impression of the examination and, with closer inspection, can give you specific study direction. For example, by comparing the number of items in each category, you can determine the relative importance given to each category on the examination.

  Content Area	Number of Items  **CHA Exam CHT Exam	Number of Items  CHS Exam
  1. General Laboratory Skills and Specimen Requirements  Specimen Requirements Laboratory Safety Laboratory Maintenance	10	9
  2. Reagent Preparation  Prepare Solutions, Stains, and Gradients Prepare Serological Reagents Prepare Reagents for Molecular Assays	15	16
  3. Methodology  Cell and Serum Preparation Serological Assays Molecular Biology Assays	40	29
  4. Test Results Interpretation  Serological Results Molecular Biology Assays Results Reporting	40	37
  5. General Histocompatibility Testing Principles and Theory  Major Histocompatibility Complex (MHC) Immunogenetics Molecular Genetics Basic Immunology and Serology	30	25
  6. Quality Assurance  Reagents Instrumentation/Equipment Documentation Compliance	15	19
  7. Supervisory Functions/Management (CHS only) Staffing Cost Management Laboratory Operations	N/A	15
  TOTAL	150	150

  ---

  More detailed content outlines based on the job analysis outlining the specific tasks in Candidate Handbook (101KB, PDF)

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  Home > Suggested Seminars

  Suggested Seminars

  Applicants may also wish to participate in some of the following review seminars and courses.

  AFDT Histocompatibility Basic Course. A four-day basic program in histocompatibility testing including immunology and genetics. Call (804) 323-9890 for more information.

  AFDT Histocompatibility Specialist Course. A 10-day intensive program in histocompatibility testing including immunology and genetics.  Call (804) 323-9890 for more information.

  * The Basic Course is offered biennially and alternates with the Specialists Course byAFDT. Call (804) 323-9890 for more information.

  ASHI Annual Meeting. This meeting is held annually in the fall. Call the ASHI Executive Office at (856) 638-0428 for more information.

  ASHI Regional Educational Workshops.

  * All ASHI Regional Educational Workshops are held annually in the spring. Contact the ASHI Executive Office for more information (Phone:  (856) 638-0428, Fax: (856) 439-0525, E-mail: ).

  International Histocompatibility Workshop and the International Congress of Histocompatibility and Immunogenetics (IHWC). Call (206) 667-6990 or Fax: (206) 667-6969 for more information.

  American Society for Histocompatibility and Immunogenetics

  

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  Home > Publications

  Publications

  The American Society for Histocompatibility and Immunogenetics sponsors several publications. Human Immunology, accepts contributions of original work in the field of immunogenetics. The journal is published 12 times a year by Elsevier Science. Full text articles are available on line for ASHI members. ASHI Quarterly contains news, scientific articles and information of interest to the membership. The Membership Directory, published each Spring, lists complete contact information for all members, Board of Directors, Committees and histocompatibility laboratories. ASHI publishes patient information brochures describing the role of histocompatibility testing in solid organ and bone marrow transplantation. The ASHI Laboratory Procedure Manual provides current protocols for test procedures, quality control and quality assurance practices. ASHI sponsors the publication of books detailing investigation of the Major Histocompatibility Complex and the study of immunogenetics. The Archives have been established to organize annual meeting abstracts and short communications in the fields of Histocompatibility and Immunogenetics. Key word search is available for abstracts presented over the last several years.

  

  HHS Proposes One-Year Delay for ICD-10 Implementation

  HHS Proposes One-Year Delay for ICD-10 Implementation: Is This Good News for Clinical Pathology Laboratories?
  
  Read more: HHS Proposes One-Year Delay for ICD-10 Implementation: Is This Good News for Clinical Pathology Laboratories? | Dark Daily http://www.darkdaily.com/hhs-proposes-one-year-delay-for-icd-10-implementation-is-this-good-news-for-clinical-pathology-laboratories-51112#ixzz1v9Yz2PtG

  READ MORE > >

  The American Society for Microbiology Award Nominations

  The American Society for Microbiology (ASM) is dedicated to acknowledging the best in microbiology.  ASM administers 28 scientific achievement awards. 

  READ MORE > >

  2012 Call for Award Nominations

  2012 Call for Award Nominations

  
  

  READ MORE > >

  2012 Call for ASHI Board Nominations

  The ASHI Nominations Committee encourages ASHI members to nominate candidates for all available board positions

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  Leading Global Cell Therapy Organizations Support U.S. Department of Justice Appeal of Ruling

  (Corrected Copy)

  MINNEAPOLIS, Jan 23, 2012 (BUSINESS WIRE) -- A coalition of nine leading international health organizations today issued a statement supporting the U.S. Department of Justice's appeal of the Ninth Circuit Court ruling that allows certain marrow donors to be compensated. Filed Jan. 17, the Justice Department's appeal cites the potential for serious health risks to patients and donors if the ruling stands.

  Approximately 5,000 patients each year in the United States receive marrow transplants from unrelated donors to treat leukemia, lymphoma and a number of other diseases. The marrow is a source of stem cells that are critical to restoring the immune system for these patients. Two techniques are used to extract these stem cells. The first draws marrow directly from the donor's hip bone and the second moves the stem cells out of the bone marrow and into the bloodstream using a stimulating hormone, and then collects peripheral blood stem cells (PBSCs) in a procedure similar to the collection of platelets from blood donors.

  READ COMPLETE ARTICLE HERE
  http://www.businesswire.com/news/home/20120123006041/en/CORRECTING-REPLACING-Leading-Global-Cell-Therapy-Organizations

   

  READ MORE > >

  CPT Informational Page

  ASHI is pleased to provide this CPT Informational page for the convenience and education of the HLA community.  Please be aware that sometimes the links may have vendor or third party associations which ASHI neither supports nor promotes.  Registration may be required for access to related articles. ASHI is not responsible for emails received from the vendor or third party.  

  http://www.ashi-hla.org/news/cptupdate/

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  CPT December 2011 Update

   

   

  
  Medicare has provided some additional information about CPT coding for genetic tests in 2012.  While they will only accept the current stacking codes for 2012, they are requesting that labs bill BOTH the stacking codes and the new CPT codes for genetic tests (including HLA and chimerism).  They are requesting an estimated charge be attached to the new codes.  They will not pay this charge, but they wish information for developing a charge structure.   See links below to a CMS newsletter and also an article about this request.  In addition, a link is provided for the CMS Clinical lab fee schedule for 2012, for your information.
  

  
  

   

  http://www.genomeweb.com//node/1002586?hq_e=el&hq_m=1165578&hq_l=3&hq_v=5600a24afa

   

  https://www.cms.gov/MLNMattersArticles/downloads/MM7654.pdf   (pages 3-4)

   

  http://www.cms.gov/ClinicalLabFeeSched/

   

   

  READ MORE > >

  URGENT! ASHI Member Responses Needed to UNOS Proposal

   

  DEADLINE DECEMBER 23!
  

   

  Dear ASHI Members,

   

  Upon further review of the UNOS proposals out for public comment, it was discovered that the proposed revisions to the UNOS bylaws would have a significant negative impact on the amount of HLA training necessary to direct a histocompatibility laboratory. 

   

  While ASHI is going to officially comment on these proposals again as a unified group, it is important to remember that even though we represent Histocompatibility professionals, ASHI's official comment is viewed by OPTN/UNOS as a single comment. Thus, it is important that each of us responds to UNOS individually on these proposals, so that the final revisions of their bylaws truly reflect the specific education and experience necessary to direct a Clinical Histocompatibility Laboratory and provide proper supervision of day-to-day testing.

   

  Our concerns regarding these proposed revisions are  <<click here to read more.>> 

   

   

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  Feedback requested by January 24, 2012 on proposed National Patient Safety Goal (NPSG)

  Proposed National Patient Safety Goal (NPSG) addressing overuse of treatments, procedures, and tests for the Hospital and Critical Access Hospital Accreditation Programs

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  International HLA and Immunogenetics Workshop and Joint Conference Abstract Submission

  Abstract Submission is now open for the International HLA and Immunogenetics Workshop and Joint Conference.  You're invited to participate in the joint conference of: 

   
  - International HLA and Immunogenetics Workshop Conference (IHIW)
  - 26th European Immunogenetics and Histocompatibility Conference (EFI)
  - 23rd British Society of Histocompatibility and Immunogenetics Conference (BSHI)
   
  Abstract submission is now open
  Abstract Submission Deadline: 1st February 2012
   
  http://ihiwefibshi.org/

  READ MORE > >

  37th Annual Meeting Posters and Abstracts

  Posters and Abstracts submitted to the 37th Annual Meeting may be viewed via the following links:

  READ MORE > >

  AST Annual Scientific Exchange

  ASE is for clinicians AND basic scientists.  There is an almost equal distribution among basic, clinical, and translational abstracts at ASE, and almost every session includes an Expert Commentary to bridge the gap between basic and clinical. ASE shows you the clinical implications of basic work and the basic questions raised by clinical work. This analysis is critically useful, but often overlooked at other transplant meetings.

  ASE is for fellows AND senior faculty. ASE is also dynamic because it is designed just as much for senior faculty and PIs as it is for young investigators and trainees. Both sides benefit from the high level of interaction and discussion that takes place: trainees receive critical feedback that is scarce at other meetings, but which they need desperately. Senior faculty can discuss research in more detail than at other meetings, which opens the door to collaborations and new research directions. This level of interaction is simply not possible at larger meetings.

  We hope you will join us in San Antonio December 1-4 for what is sure to be another highly acclaimed Annual Scientific Exchange. Full Program Available Online   

  http://2011.ast-ase.org/

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  IT’S HERE!  The ASHI Annual Meeting App

  
  Access information about the ASHI 37th Annual Meeting via your smart phone or mobile device.  Create a customized schedule, find room locations and view exhibitor information right in the palm of your hand.*

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  In Memoriam - Dr. Charles Bernard Carpenter

  Dr. Carpenter was a founding member of the American Society for Histocompatibility and Immunogenetics and served as ASHI president from 1977-78.
  

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  Proposed Revisions to the ASHI Standards

  Proposed Revisions to the ASHI Standards

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  An Opportunity to Advocate for our Renal Transplant Patients

  
  New bipartisan legislation introduced by Senators Durbin and Cochran would assist thousands of renal transplant patients under the age of 65 who are being cut off from Medicare after 36 months by extending coverage of immunosuppressive drugs.  To learn more about The Comprehensive Immunosuppressive Drug Coverage for Kidney Transplant Patients Act and what you can do to help get this legislation passed, see http://www.kidney.org/news/newsroom/nr/Durbin_Cochran.cfm

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  INFORMATION UPDATE - ASHI’s Call to Action: Public Comment

   

  FDA MAILING ADDRESS - UPDATED
  

  Dear ASHI Member:

  
  On June 27th we notified you that the FDA recently published a DRAFT guidance document regarding Research Use Only/Investigational Use Only (RUO/IUO) products. We hope you have already submitted your comments through the FDA web site. If you have not, the DRAFT guidance document can be found here and the page for submission of comments can be accessed here.  Deadline for public comment is August 29, 2011.  

  Since then, the ASHI Board of Directors has determined that the issue of proposed FDA oversight of laboratory developed tests (LDTs) has become so critical that more needs to be done. Thus, we are asking you to write to the FDA as well as your elected officials regarding this topic which is very important to our laboratories, transplant programs and patients. To assist you in this effort, ASHI has drafted the attached template that can be customized and sent to the FDA and/or your government official. The address for the FDA is on the letter, and links

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  International Summer School - Deadline Extended

  Deadline EXTENDED - AUGUST 3, 2011

  This year's meeting is being organized by ASHI (American Society for Histocompatibility and Immunogenetics) with support from APHIA (Asia-Pacific Histocompatibility and Immunogenetics Association) and EFI (the European Federation for Immunogenetics). The meeting will be held at the Sheraton Old San Juan in Puerto Rico from September 19-22, 2011. The deadline for submission of documentation to attend has been extended to August 3, 2011.

  For more details, click here.

  
  

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  CMS Issues Proposed Rule to Retract Physician Signature Requirement - 7/6/11

  June 30—After months of silence on the issue, CMS officials are proposing a rule to retract the physician signature requirement on test requisitions paid under the Clinical Laboratory Fee Schedule (CLFS), acknowledging that the policy could negatively impact patient care and would be difficult to implement. CAP was among the first and strongest opponents of the requirement when CMS first proposed it in the 2011 Physician Fee Schedule (PFS).

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  ASHI and The Joint Commission Announce A Cooperative Agreement

  June 16, 2011

  
  

  The Joint Commission and the American Society for Histocompatibility and Immunogenetics (ASHI) announce a cooperative agreement to recognize histocompatibility (HLA) accreditation. ASHI will now be accepted as the deemed accreditor for transplant testing services in Joint Commission facilities, effective July 1, 2011.

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  ASHI AT FOCIS 2011 - Joint Symposium Eligible for ABHI CECs

  The Federation of Clinical Immunology Societies (FOCIS) is the leading collaborative forum for education, research and networking across the broad field of clinical immunology. ASHI has partnered with the American Society for Transplantation (AST) and the Association of Medical Laboratory Immunologists (AMLI) to sponsor two exciting Member Society Symposia. Plus, we have just learned that ABHI has approved the ASHI/AMLI symposium for three (3) hours or .45 CECs - another good reason to attend!

  READ MORE > >

  Conference Announcement - HLA Epitope Matching in Clinical Transplantation

  Conference Announcement - HLA Epitope Matching in Clinical Transplantation June 15-16, 2011

  READ MORE > >

  Law passed requiring CT insurance providers to cover bone marrow tests done at ASHI-accredited labs

  Legislation co-sponsored by State Representative Tony Hwang (R-134) which would require health insurance providers to cover bone marrow testing has now passed the State House of Representatives.

  READ MORE > >

  Lab Professionals Week - April 26-30, 2011

  National Medical Laboratory Professionals Week (NMLPW) is an annual celebration of the medical laboratory professionals and pathologists who play a vital role in every aspect of health care.

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  2011 Call For Abstracts

  The 2011 abstract submission site is now live!
  
  All abstract submission will be peer reviewed and considered for oral or poster presentation.  Accepted abstracts will be posted on the ASHI Web site and published in the supplement Human Immunology, which will be available on site at the Annual Meeting.
  
  Submission Site:         www.call4abstracts.com/ashi/
  Submission Deadline:  May 13, 2011 11:59 PM (CDT)

  READ MORE > >

  Award Nominations Now Open

  Each year the American Society for Histocompatibility & Immunogenetics (ASHI) sponsors several awards to recognize scientific accomplishments and contributions to the fields of histocompatibility and immunogenetics, and service to the society. ASHI is currently accepting nominations for the following awards:

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  AFDT Basic Histocompatibility Course

  Purpose: Provide the technician/technologist with a wellrounded background in basic transplant immunology and related laboratory skills and to provide the transplant fellow with basic immunology. Objective: Meet the needs of the beginning HLA technician/technologist by providing pertinent information about HLA testing, methodologies, and information necessary to meet the ASHI Statement of Competency.

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  Conference Announcement - “HLA Epitope Matching in Clinical Transplantation”

  This two-day conference addresses the characterization of antibody-defined HLA epitopes and their significance in compatibility testing for transplantation. Analyses of antibody reactivity patterns specific for class I, class II and MICA epitopes are applied to determining mismatch acceptability for sensitized patients and immune monitoring following transplantation. Information about HLA epitope immunogenicity and antigenicity may lead to new donor selection strategies based on permissible mismatching.

  READ MORE > >

  ASHI’s Response to MEDCAC regarding the use of RBC transfusions vs ESA in renal transplant patients.

  The Medicare Evidence Development & Coverage Advisory Committee (MEDCAC) held a January 19, 2011 hearing on “The Impact of Erythropoiesis Stimulating Agents (ESA) on Renal Transplant Survival.” Dr. Susie Leffell presented comments on ASHI’s behalf. To read her

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  ASHI teams up to fight back against childhood cancer

  Through the Dreyer's and Edy's® brands, ASHI teams up with Nestlé® to fight back against childhood cancer.  Click here to learn more about the "Cool Comfort Coupon" campaign.

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  Immune Tolerance Network (ITN) Symposium

  In celebration of the Immune Tolerance Network's (ITN) 10th anniversary there will be a free one-day symposium, “Ten Years of Tolerance,” on November 1st, 2010, on the NIH campus in Bethesda, MD.

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  Harmonization of Histocompatibility Typing Terms Statement

  The purpose of the Harmonization of Histocompatibility Typing Terms Statement is to recommend and to initiate discussion regarding terminology, definitions of resolution levels, format for reporting HLA assignments and match reporting for transplantation. This initiative began in February of 2010.  Representative members of the groups listed below have met via conference calls over the past seven months to prepare this document. We now request and welcome your participation in this effort.

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  Proposed Amended ASHI Bylaws - Response to Public Comment

  On June 1, 2010, the Bylaws Committee circulated the proposed amended ASHI Bylaws to the membership for comment. The committee has reviewed, discussed and carefully considered all of the comments and recommendations received from the membership.  A summary of the comments we received

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  The American Academy of Microbiology Award Nominations

  The American Society for Microbiology (ASM) is dedicated to acknowledging the best in microbiology.  ASM administers 28 scientific achievement awards. 

  READ MORE > >

  Summary of the recent FDA public meeting

  A summary of the recent FDA meeting on laboratory developed tests is available on the members only section.  To view the summary, visit:
  http://www.ashi-hla.org/members/shared-resources/

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  Request for Membership Response to Proposed Revisions to the ASHI Standards

  The Quality Assurance and Standards Committee (QAS) has been working on updates to the ASHI Standards. We propose a new definition and two new standards suggested by partner organizations and working groups.  In addition, revisions brought to our attention by other ASHI Committees and ASHI members are among the changes.

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  International Summer School

  ASHI travel stipends for the 2010 International Summer School Messolonghi, Greece

  A limited number of ASHI travel stipends are available to support students/scientists who wish to attend the 2010 International Summer School.  Summer school details are available

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  Annual Meeting Registration NOW OPEN!

  Is Hollywood calling your name?  Don't miss the ASHI 36th Annual Meeting in Hollywood, Florida September 26th - September 30th, 2010.  Securing your spot at the 36th Annual Meeting is just a click away.  Register Online Now or download the registration form.

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  FDA AMR Public Workshop

  The Food and Drug Administration (FDA) is announcing a public workshop regarding scientific issues in clinical development of medical products (i.e., human drugs, therapeutic biological products, and medical devices) for prophylaxis and/or treatment of acute antibody mediated rejection (AMR) in kidney transplant recipients.

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  Call for Volunteers

  Are you interested in serving on an ASHI committee for the 2010 - 2011 term?

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  ASHI Bylaws Committee Request Membership Response to Amended Bylaws

  Dear Colleagues,
  The ASHI Bylaws Committee, consisting of Julie Ward, Siva Kanangat, and Lori Osowski, is submitting an amended version of the ASHI Bylaws to the Society members for comment on two (2) revisions:

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  Haiti Kidney Transplant Program’s Request for Financial Support

  Haiti hospitals were heavily damaged during the earthquake that struck on January 12, 2010.  ASHI has received a request for financial support from The Haiti Transplant Program that we'd like to share with our members and their facilities.

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  2010 International Summer School - 4/20/10

  The Seventh International Summer School on Immunogenetics - 2010

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  New Version of HLA Nomenclature Launched April 2010 - 4/16/10

  The NMDP has updated their website dedicated to the nomenclature change with new language as well as training that was conducted for transplant programs and cord blood banks.

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  Institute for Justice Coalition press release - 3/23/10

  Institute for Justice Coalition press release

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  Institute for Justice Coalition - 3/23/10

  ASHI is now a member of the Institute for Justice Coalition.

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  The HLA Nomenclature Report 2010 is now published - 3/22/10

  The HLA Nomenclature Report 2010 is now published.

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  Award Nominations Now Open - 3/17/10

  Each year the American Society for Histocompatibility & Immunogenetics (ASHI) sponsors several awards to recognize scientific accomplishments and contributions to the fields of histocompatibility and immunogenetics, and service to the society.
  

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  2009 ASHI Standards available online - 2/12/10

  The 2009 ASHI Standards are available online at http://www.ashi-hla.org/lab-center/accreditation/forms/standards/.

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  HLA Nomenclature Changes effective April 1, 2010

  With the increasing number of HLA alleles described, the World Health Organization (W.H.O.) Nomenclature Committee for Factors of the HLA System decided to introduce changes in the way the alleles are designated and named.   These changes will be effective April 1, 2010.

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  NMDP- Notice of Upcoming Release of Request for Proposal - 12/4/09

  The National Marrow Donor Program  (NMDP) anticipates releasing a Request for Proposal

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  Updated Allele*Frequencies in Worldwide Populations website - 11/12/09

  Please visit the Allele*Frequencies in Worldwide Populations http://www.allelefrequencies.net/ and contribute to the growing allele frequencies from around the world. 

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  The Joint Commission - Laboratory Accreditation Program - 11/2/09

  The Joint Commission released the 2010 National Patient Safety Goals for the laboratory accreditation program.

   

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  Attention Independent Histocompatibility Laboratories - 9/3/09

  Effective 8/3/2009 CMS has awarded the contract for the fiscal intermediary of all Independent Histocompatibility Laboratories

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  ASHI travel stipends available to the 2009 International Summer School

  2009 International Summer School -ASHI travel stipends available to support students/scientists

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  35th Annual Meeting Registration is Open! - 8/4/09

  35th Annual Meeting Registration is Now Open! 

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  Public comment period for the NetCord-FACT Cord Blood Standards - 7/23/09

  NetCord and The Foundation for the Accreditation of Cellular Therapy (FACT) have published the Fourth Edition of the NetCord-FACT International Standards for Cord Blood Collection, Processing, Testing, Banking, Selection, and Release

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  HLA Nomenclature Update - 6/16/2009

  HLA Nomenclature Update - 6/16/2009

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  Submit your abstracts now!

   

   The ASHI 35th Annual Meeting Call for Abstracts Submission Site is Now Live!

   

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  Nominations Now Open for Five ASHI Awards

  Each year the American Society for Histocompatibility & Immunogenetics (ASHI) sponsors several awards to recognize scientific accomplishments and contributions to the fields of histocompatibility and immunogenetics, and service to the society.

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  ASHI to Host Three Educational Workshops in 2009

  ASHI will host a series of regional educational workshops to further advance the science, education, and application of immunogenetics and transplant immunology.

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  ASHI Meeting Highlights Breakthroughs in Histocompatibility and Immunogenetics Research

  ASHI wrapped up its 34th Annual Meeting in Toronto as a success.

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  ASHI Launches Extended Membership Program

  As a professional society, ASHI works to advance the science and application of histocompatibility and immunogenetics by providing members with valuable educational opportunities, publications, professional recognition and a forum for the exchange of information. Now, ASHI is making it more affordable for up-and-coming professionals to experience similar benefits, while continuing to advance the association and the field.

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