E-Newsletter 3rd Edition

September 2011

A Message from ASHI's Secretary, Dorothy Levis

Fall is arriving and our annual meeting is just around the corner.  I look forward to seeing so many friends each year as well as attending the sessions. ASHI has been busy preparing for the International Summer School in addition to our annual meeting.  September is time for ABHI certification exams and I send best wishes to all who are taking their exams at this time. Fall also is the time for labs to plan for next year's proficiency testing and at the meeting we will hear about some exciting enhancements to the surveys.

Many ASHI members have responded to the call for volunteer opportunities and will soon be hearing about upcoming committee activities at the annual meeting. Watch for announcements for these committee meetings.  The pre-meeting accreditation inspector's workshop will train volunteers interested in doing inspections and will also help laboratories learn more about the inspection process.  Seasoned inspectors need to attend the afternoon session every two years or do on-line review sessions to stay current.  The Accreditation Update session always brings the newest information from the Accreditation Review Board (ARB), Quality Assurance and Standards (QAS), Proficiency Testing (PT) and Centers for Medicare and Medicaid (CMS). Attending this session helps prepare your laboratory for its next inspection.  Also, this year there will be a special workshop on CPT codes for Histocompatibility. 

We hope our members are enjoying this e-newsletter with its timely updates between the Quarterly issues.  Melissa Roberts is your contact for comments or suggestions for this information. She may be contacted via .

ASHI 37th Annual Meeting/ Registration

Early Registration Deadline: September 19  
(Register Now - Click Here)

The ASHI 37th Annual Meeting is only one month away.  If you haven't registered yet, there is still time to make the early registration deadline and save up to $135 on registration fees.

Be sure to take advantage of all that this year's meeting has to offer.  Beginning with new morning sessions aimed at providing attendees with an overview of the day's theme, and including a full day dedicated to both bone marrow and solid organ transplantation, this year's meeting has been designed with the attendees needs in mind.

Three Ways to Register

1. INTERNET

For online registration, click here.

2. FAX

Fax your completed registration form, including payment information to ASHI at: 877-716-6404
 
3. MAIL
Mail your completed registration form, including payment information to:

ASHI
15000 Commerce Parkway, Suite C
Mount Laurel, NJ 08054
All checks must be made payable to ASHI, in U.S. dollars and drawn on a U.S. bank

To register, download the Annual Meeting brochure or for more information, click here.

Get 'In the Groove' with Soul Incision at the House of Blues

Tickets are still on sale for ASHI's Annual Banquet at the House of Blues.

Eat, drink and get jazzed in true New Orleans style at this unique venue.  Located in the heart of the world famous French Quarter, the House of Blues is just a short walk from the Sheraton New Orleans. Tickets for this soulful event include an open bar and a hearty buffet of local favorites such as Catfish Bites, BBQ Brisket and Pistolettes. Cut a rug on the spacious dance floor as you listen to the ever popular stylings of Soul Incision. Don't miss the chance to enjoy classic southern hospitality with ASHI in this unique and down to earth atmosphere.

Top 3 Reasons to Stay at ASHI Annual Meeting Host Hotel
Reservation Deadline: September 14

ASHI Discounted Room Rate:  $239+tax (rate includes complimentary Internet)
Online Reservations: www.starwoodmeeting.com/Book/ashi1
Toll Free Reservations: (800) 325-3535

The Sheraton New Orleans is the official host hotel for the ASHI 37th Annual Meeting.  The reservation deadline is quickly approaching, so book now!

1.    Great Location
The Sheraton New Orleans is in the center of it all.  Visit Bourbon Street, ride the Canal Street Trolley or stop in Cafe Du Monde for a cafe au lait and beignet.  By staying at the Sheraton New Orleans, youíll be surrounded by all that New Orleans has to offer. 

2.    Great Convenience
Cut your travel time to just a minute by staying steps away from all meetings, receptions and events. Eliminate the stress commuting to the Annual Meeting when all you have to do is open your hotel room door and hop on the elevator.  Networking opportunities are everywhere when you stay at the host hotel.  Network in the lobby, in the elevator or even at the pool!

3.    Support ASHI
ASHI has worked diligently with the hotel to provide the best rate and service as a convenience for meeting attendees. In order to reserve the required meeting space, ASHI has a contractual obligation to fill a specified number of sleeping rooms.

If reservations are made at other hotels, ASHI will be at risk for defaulting on this obligation. Failure to meet the contractual obligation will result in ASHI paying higher costs (penalties) to the hotel. This will likely force ASHI to increase annual registration fees for future meetings.

For more information the Sheraton New Orleans, click here.

MEMBERSHIP COMMITTEE SPOTLIGHT

Over the last several years, the ASHI Membership Committee has been working to update the ASHI membership categories and benefits so that they will be most useful and cost-effective to those in our field.  The Technologist Membership category was added several years ago and now represents nearly 20% of our total membership.  More recently, the Affiliate Membership category was added to allow vendors and consultants to be an official part of our organization.  Some of the benefits of Affiliate Membership include access to ASHI-U and Human Immunology on-line as well as the ability to serve on ASHI committees.  We have also increased the benefits for Institutional Members. Institutional Members can now receive discounted registration for up to 6 individuals for the ASHI Regional and Annual meetings in addition to continuing education credits from 24 modules from ASHI-U, free of charge.  The Institutional Members are also eligible to receive free access to Human Immunology online or can opt for a paper copy of Human Immunology for only $30.  All ASHI members continue to receive the ASHI Quarterly, have free access to ASHI-U and receive discounted registration at ASHI Regional and Annual meetings.   It is our hope that these expanded categories and benefits will encourage membership for the continued growth of our organization.  For specific descriptions of all categories, please refer to the Membership page of the ASHI website at http://www.ashi-hla.org/about/membership/.


Current membership totals by category

ASHI's Recent Accomplishments in National Transplant and Laboratory Affairs

For many ASHI members, awareness of ASHI's activities is limited to attendance at annual and regional meetings, having and performing lab inspections, subscribing to the PT program, reading the Quarterly and Human Immunology, and completing continuing education from ASHI University. But there's a lot more going on behind the scenes. Most members don't realize that ASHI is heavily involved in influencing national policies on transplantation and advocating for histocompatibility laboratories and professionals.  Recently, ASHI has made huge strides in increasing our involvement with other organizations and government agencies. The following is a list of the many activities ASHI has been involved in during the past year (in no particular order):

• Entered into Cooperative Agreement with The Joint Commission (TJC) - the first organization to do so!

• Participated in The Joint Commission Liaison meeting as well as the Laboratory Professional and Technical Advisory Committee (Lab-PTAC), a group of laboratory professionals from many disciplines that reviews TJC activities as they relate to the operation and accreditation of the laboratories

• Responded to UNOS proposals including the new kidney allocation algorithm 

• Was invited to participate in the UNOS Society Leadership Roundtable to discuss issues of mutual interest

• Provided written testimony and an oral presentation to the Center for Medicare and Medicaid Services (CMS)/Medicare Evidence Development & Coverage Advisory Committee (MEDCAC) on the impact on kidney transplant graft survival of alternative modalities for treating anemia in individuals with chronic kidney diseases, i.e. red blood cell transfusions vs. erythropoiesis-stimulating agents (ESAs)

• Responded to the Technology Assessment Program at the Agency for Healthcare Research and Quality on the Impact of Pre-transplant Red Blood Cell Transfusions in Renal Allograft Rejection Commented on a Proposed Decision Memorandum issued by CMS as part of its ongoing National Coverage Analysis for ESAs in nephrology

• Attended an open meeting with a coalition of laboratory professional associations, including the American Clinical Laboratory Association (ACLA) and Association for Molecular Pathology (AMP), on the issue of Food and Drug Administration (FDA) oversight of laboratory developed tests (LDTs).

• Responded to FDA draft guidance on commercially distributed in vitro diagnostic products labeled for research use only, and investigational use only

• Initiated a letter writing campaign for ASHI members regarding FDA oversight of LDTs

• Was invited to be on the steering committee for The Office of Blood Research and Review (OBRR) Heritable Marker Workshop to clarify and provide updated regulatory and scientific information to manufacturers of CBER-regulated heritable markers in vitro diagnostic kits

• Endorsed the American Society for Transplantation (AST) document addressing the FDA's changes to the Laboratory Developed Assays rules - this document was presented on Capitol Hill and to the FDA and Department of Health and Human Services (DHHS)

• Was invited to participate as a key partner in a consensus conference on paired and chain kidney exchange by the AST Kidney Pancreas Advisory Council

• Was invited to participate in the formation of the AST Transplant Diagnostics Community of Practice

• Held a Transplant Histocompatibility Conference to address concerns regarding the use of solid-phase HLA antibody test results for assessing risk in organ transplants.

• Participated in the AMA Molecular Pathology Coding Workgroup and attended a CMS meeting on CPT codes for molecular diagnostic tests. Made recommendations on National Correct Coding Initiative (NCCI) edits and Medically Unbelievable Edits (MUE) for HLA codes.

• Participated in a coalition with the AMP and the American College of Medical Genetics (ACMG) to pursue PhD status as a Qualified Healthcare Practitioner for Molecular Genetic studies in Genetics and Oncology

• Collaborated with the AABB in a response to the DHHS's Request for Information regarding the development of a public-private partnership to establish a national biovigilance system to prevent malignancies and infections from being transferred by blood, organ and tissue donors

• Participated with ASBMT and NMDP on the Harmonization of Histocompatibility Typing Terms Group

• Commented on proposed changes to NMDP standards

• Was invited to join the Worldwide Network for Blood Marrow Transplantation (WBMT) and participate in planning a scientific symposium at the BMT Tandem meetings and EBMT in 2012.

• Was invited by the Foundation for the Accreditation of Cellular Therapy (FACT) and the Joint Accreditation Committee of ISCT-EBMT (JACIE) to review and comment on the FACT-JACIE International Standards for Cellular Therapy Product Collection, Processing, and Administration

• Was invited to join the Coordinating Council on the Clinical Laboratory Workforce (CCCLW) to promote clinical laboratory education to ensure a qualified workforce for the future

• Partnered with the European Federation for Immunogenetics (EFI) and the Asia-Pacific Histocompatibility and Immunogenetics Association (APHIA) to organize the 8th annual International Summer School for Immunogenetics

• Partnered with the Association of Medical Laboratory Immunologists (AMLI) and the AST Basic Science Advisory Council to host two satellite symposia at the 2011 FOCIS annual meeting

• Collaborated with FOCIS on a call for clinical trial contributions for their Translational Immunology Update ePublication

• Was invited to participate in program planning for the FOCIS 2012 meeting

• Was invited to join the National Medical Laboratory Professionals Week coalition as a supporting organization

• Was invited to have an entry in a directory of CMS-deemed health care accrediting organizations.

ASHI would like to thank the many volunteers who have spent countless hours representing ASHI at meetings and writing comments and testimonials on our behalf. Without them, we could not accomplish our vision of being the foremost authority and leading educational resource in immunogenetics and histocompatibility and to improve the quality of human life and health through the translation and implementation of scientific innovations to clinical practice. The many invitations we have received to participate in coalitions, workgroups and program planning committees speak to our increased visibility in the national and international transplantation arena.

ASHI-U and Lab Manual Update

The Education Committee would like to provide an update to membership regarding the status of ASHI University. The initial model for ASHI-U successfully provided a platform for technologists to engage in educational modules while earning necessary continuing education credits. Initially, our next steps were to build more modules until we covered all techniques and methodologies employed in the histocompatibility lab.

Coinciding with the development of ASHI-U was the growing need to update the ASHI Lab Manual. Members of the committee asked to address the needs of revising the Lab Manual and those from ASHI-U conceived a product which is complimentary to each (ASHI-U and the Lab Manual) while maintaining their own distinct value to membership. The end product will be a combined web-based educational resource and lab manual available to all members as a benefit to membership.

The ASHI Board of Directors has charged the Education Committee with developing this new model. Development of new modules has stopped and we have begun revising current ASHI-U modules to provide a distinct lab manual section which will eventually be a stand alone product as well as have a link to the corresponding ASHI-U module.

This new product will be a member benefit and we need members to assist us in completing these modules to meet our very aggressive timeline for completion. If you have previously authored a section of the Lab Manual or ASHI-U, we need your help. You have already done much of the work and some simple changes in format will allow you to be recognized as a published author.

If you previously missed out on the opportunity to author an ASHI-U module or section of the Lab Manual and have an interest in being an author, or have an interest in reviewing modules for scientific content, please contact us via the ASHI-U website or by contacting Melissa Roberts at Association Headquarters, .

Dean Sylvaria & Lori Osowski
Co-chairs, Education Committee

This E-Newsletter is sponsored by:

Life Tech Submits 3500 CE Analyzer and HLA Typing Kits for FDA 510(k) Clearance

Life Technologies announced on August 1st, 2011, in a press release, that the company had completed its clinical trial and had subsequently submitted the 3500 Dx Genetic Analyzer capillary electrophoresis sequencer and Secore® HLA typing kits for US Food and Drug Administration 510(k) clearance.  If cleared, the assay would be the first sequencing-based HLA typing test to receive clearance from the FDA.  To read the press release click here:
http://www3.appliedbiosystems.com/cms/groups/mcb_marketing/documents/generaldocuments/cms_097440.pdf

In response to the July, 2011 IMGT database update of over 400 allele discoveries, updates have already been made to the Secore® product line and uTYPE® analysis software.  Product line updates include the addition of 3 new GSSP kits for additional ambiguity resolution, and references of the July, 2011 IMGT release have been built-into the analysis software for the most up-to-date data analysis.  Continual maintenance of kits and software is the key to being able to deliver 100% resolution, 100% of the time.

Life Technologies is planning to exhibit at the annual ASHI meeting this October, highlighting the Secore® SBT workflow.  The company will also host a luncheon at the conference, including speakers from one of the US clinical trial sites and a leading registry.

American Society for Histocompatibility and Immunogenetics

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Home > Travel Expenses

Travel Expenses

The following are approved forms and documentation for use when planning and submitting reimbursement request for ASHI related travel. We advise bookmarking this page for quick access and most up-to-date documentation.

Best Practices Travel Guidelines

Financial Policy - Board Approved 

Reimbursement Request Form

 

 

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Home > 2011 Elections

2011 Elections

To download the 2011 Election Bios, click here.

Marilyn S. Pollack, PhD, D(ABHI)  -  President-Elect Candidate

Marilyn Pollack has been a dedicated and hard working member of ASHI since the original AACHT days and sincerely welcomes this opportunity to serve ASHI in an even more important capacity than ever before. In the past, she has served as a Councilor, as the Secretary and member of the then-called ASHI Executive Council, as the Chair of the ASHI QA/S Committee, as the ASHI Chair of the Joint ASHI-CAP Proficiency Testing Committee, as an ASHI ARB Commissioner, Co-Chair and Program Director (with a liaison relationship with our CMS regulating organization) and, most recently, as the ASHI Proficiency Testing Program Director.   She has also been the Director of a National Marrow Donor Program Donor Center, a member of the UNOS Histocompatibility Committee, the Chair of the then-called American Society of Transplant Physicians Membership Committee and a member of the AABB Relationship Testing Standards Program Unit. All these various activities have provided her with a very broad understanding of how various professional organizations can work together to promote common interests and about ASHI’s own structure and resources that can be used to help answer clinical and laboratory questions from individual ASHI members.

Marilyn is currently a Professor of Pathology at the University of Texas Health Science Center and Director of the University Health System’s Histocompatibility and Immunogenetics Laboratory in San Antonio. Her laboratory performs clinical testing for deceased and living donor organ transplant candidates, for related and unrelated donor HPC transplant candidates, in support of transfusion service patients (platelet transfusion candidates and possible TRALI cases) and for assessment of risk for various HLA associated diseases and drug hypersensitivity reactions. She has continuously participated in grant-supported research activities related to clinical histocompatibility testing, most recently in relation to the role of donor-specific antibodies in lung transplant recipients, and has over 200 publications in our field. This broad and continuous clinical experience helps ensure that she keeps well informed about new test procedures and the ASHI organization’s role in keeping its members well informed about important new changes. She is committed to continuing to help make ASHI shine as the most important professional organization in transplant immunology and immunogenetics.

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Judy Baker, CHS, I(ASCP) – Vice President of Operations Candidate

Judy Baker has been in histocompatibility for 30 years and has served in a number of roles in both ABHI and ASHI including Continuing Certification member and chair for ABHI, vice president and president of ABHI, 3 years as the editor of the ASHI Quarterly, 5 years as an ARB commissioner, a member of the Board of Directors of ASHI, and as secretary of ASHI. She is the manager of the Transplant Immunology Lab at Baylor University Medical Center in Dallas. Her hobbies are travel, photography, Zumba, and art. She is married, has one son and 3 Tibetan terriers.

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Malek Kamoun, MD, PhD – Doctoral Candidate for Board

Dr Kamoun is a Professor of Pathology and Laboratory Medicine at Penn. He received his training in human immunogenetics in Dr. Jean Dausset’s laboratory in Paris, France. He is currently the Director of the HLA lab at Penn; he has over 20 years of extensive experience in clinical histocompatibility. He has published over 115 peer -reviewed research papers.  His current research interests focus on understanding the significance of HLA amino acid polymorphism in clinical transplantation and autoimmunity as well as the effects of B cell alloresponse and anti-HLA antibodies on allograft outcomes. He has served more than 3 years on several ASHI and UNOS committees.

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James M. (Jim) Mason, PhD – Doctoral Candidate for Board

BS (Chemistry), University of Memphis and PhD (Pathology) University of Tennessee, Memphis. Pathology Faculty UT, Memphis, 1972-89.  LabCorp Director of HLA and Parentage Testing Laboratory (1989-2002). Currently Laboratory Director Mid-South Transplant Foundation, Memphis TN (1999 – present). NICHD Lectureship (Pathogenesis of SIDS); Astra Pharmaceutical Award, Society of Perinatal Obstetrics; Outstanding Service Award, Human Identity Trade Association (HITA). HITA Board of Directors (President, 1993); ASHI - Finance /Audit Committee, Quality Assurance and Standards Committee (Chair 2005-2008), Proficiency Testing Committee; AABB - Histocompatibility Testing Committee, Transplantation Immunology Committee (Chair 1989-92), Relationship Testing Standards Project Unit (SPU), Molecular Testing SPU. Sixty-two publications. Two Patents.

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Lorita Rebellato-deVente, PhD, MS, D(ABHI) – Doctoral Candidate for Board

Lorita Rebellato-de Vente, Ph.D., D (ABHI) is an associate professor in the Department of Pathology at East Carolina University and Director of the Histocompatibility Laboratory at Pitt County Memorial Hospital, Greenville, North Carolina. Lorita served as both member and chair of the ASHI bylaws committee. She served in the ABHI CHS/CHT examination committee and in the director’s credentials committee. Currently, she is a member of the ABHI director’s exam committee.

Lorita is involved with teaching and has an interest in post-transplant monitoring. She has been studying antibody responses in patients transplanted at East Carolina University.

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Walter Herczyk, MT(ASCP), CHS – Non-Doctoral Candidate for Board

Walter Herczyk is currently the manager for the Transplant Immunology and Immunogenetics Laboratory at the University of Chicago Medical Center. Walt has worked at Allegheny General Hospital, University of North Carolina and Duke University Medical Center during his 22 years in the field of HLA.

Since becoming a member of ASHI, Walt has actively been involved with the organization by his participation at meetings, involvement on committees and general support for the advancement of transplantation.

Walt plans on bringing his hard work and dedication to the ASHI Board as he has done in all his commitments to ASHI.

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Donna P. Lucas, MS, CHS – Non-Doctoral Candidate for Board

Donna Lucas, MS, CHS is the senior research manager at the Johns Hopkins Immunogenetics Laboratory where she has worked and grown since 1980. She has been an active member of ASHI since 1994. She has served as a commissioner on the Accreditation Review Board, as a member of the Standards Committee, and as a laboratory inspector. She has been involved in 4 workshops at annual meetings and a presenter at 2 regional meetings. She has been a contributing author for the ASHI Manual.

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Mickie McCarter, BS, MT(ASCP), CHT, CHS(ABHI) – Non-Doctoral Candidate for Board

Mickie McCarter, BS, MT (ASCP), CHT, CHS (ABHI) is the supervisor of DCI Transplant Laboratory at the University of Tennessee Medical Center in Knoxville, Tennessee, where she has been employed since 1992. She was responsible for the establishment and set up of the laboratory’s molecular HLA typing. She is an active member of ASHI, having served on the ASHI Proficiency Testing Committee for seven years. Her service includes three years as co-vice chair and one year as chair of the committee during the transition to the new PT program. She is currently active as a laboratory inspector for the ASHI Laboratory Accreditation Program.

Mickie is honored to be nominated to serve as a non-doctorial board member on the ASHI Board of Directors and, if elected, will work hard to contribute to ASHI’s continued movement in a positive direction. She welcomes the opportunity to serve in a new capacity.

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Dean Sylvaria, BS, CHS – Non-Doctoral Candidate for Board

Dean Sylvaria, BS, CHS(ABHI) is the supervisor of the HLA Laboratory at Beth Israel Deaconess Medical Center, Boston, Massachusetts. Dean started his career in Histocompatibility and Immunogenetics in 1993 across the street at Brigham & Women’s Hospital. He has been a member of ASHI since 1994. His professional contributions include developing and promoting ASHI University, service to the Education Committee (multiple terms), Chair of the Education Committee with responsibility for planning the ASHI Regional workshops (2008-present), service on the Audit and Finance Committee (2008-present), service as an ASHI inspector since 2000 and Commissioner for the Accreditation Review Board (2009-present), UNOS Histocompatibility Committee representative for Region 1 (2008-2010) and member of the Annual Program Planning Committee (2009-present). Dean has also held several positions on local committees serving on BWH’s Laboratory Safety Committee (1995-2007), as well as the Quality Assurance Committee and Donor Selection Committee (2007-present) for the Transplant Institute at Beth Israel Deaconess Medical Center. Dean enjoys sharing his experience and knowledge of HLA with technologists, residents and clinicians while serving the transplant community.

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Dawn Wagenknecht, MS, CHS – Non-Doctoral Candidate for Board

Dawn is the Supervisor and Manager of the HLA-Vascular Biology Laboratory at Franciscan St. Francis Health in Beech Grove (Indianapolis), IN.   A member of ASHI since the beginning of her career, Dawn has served on both ASHI and ABHI committees.  Dawn chaired the organizing committees for the 1988 and 1994 ASHI regional workshops in Indianapolis, served 4 years on the ABHI CHT and CHS Exam Committee, and was a member, then Co-Chair, of the ASHI QAS Committee.  Currently, Dawn is Co-Chairing the Harmonization of Histocompatibility Typing Terms Working Group and is the ASHI liaison to the AABB Molecular Testing Standards Unit.

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Home > E-Newsletter 2nd Edition

E-Newsletter 2nd Edition

June 2011

A Message From The Vice President Of Operations, John Hart

Just as each spring brings a renewal of nature, there are many new, exciting things happening at ASHI.  The current newsletter highlights many of the areas that continue to grow and be updated, affecting both our membership and those who interact with us through the delivery of laboratory services. 

If you are planning to attend the International Summer School, you won’t want to miss the opportunity to apply for a travel stipend.  The Proficiency Testing committee continues to improve our first class program and the Molecular Pathology Workgroup is busy with the overhaul of the Histocompatibility CPT codes.  Opportunities for ASHI members also exist with FOCIS and the IDAWG 16th International Histocompatibility Workshop survey.

All of these activities highlight the volunteer efforts of so many ASHI members.  Getting involved is one of the many ways members can contribute to our field.  If you have any comments or suggestions for future e-newsletters, please, send them to Melissa Roberts via email, .

Please enjoy this issue.

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In the Groove

Many thanks to Michael Gautreaux for participating in our online social media discussion and suggesting "In the Groove"  as the new official name of the ASHI E-Newsletter.  To get connected with other ASHI members and participate in industry-related discussions, visit http://www.ashi-hla.org/news/connect/ to get started.  Then post YOUR first discussion!

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2011 International Summer School
San Juan, Puerto Rico

ASHI announces that two travel stipends will be available to support students/scientists who wish to attend the 2011 International Summer School to be held at the Sheraton Old San Juan in Puerto Rico from September 19-22, 2011.  

An announcement regarding the details of the International Summer School and the opening of the travel stipend application process will be made soon.  In preparation for that announcement, the information below has been made available. 

Applicants for travel stipends must supply:

• Completed application
• Statement of motivation for attending this meeting
• A summary of current research
• Letter of support from their supervisor/head of department
• Curriculum Vitae

Travel stipend criteria are listed below:

• Have current ASHI membership
• The applicant must currently be enrolled or have recently completed an advanced degree (Ph.D., MD, or equivalent)
• Research and active technical staff will also be considered
• Have background slides and data (or research plan) for a 20 minute presentation to be given at the International Summer School
• Stay for the duration of the meeting

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Membership Directory

The 2011 Membership Directory is now available on the ASHI web site.  It is available in both a pdf version and an online search option.  To view the directory and verify that your contact information is correct, please log in to the Members Only section.  To correct or update your information, please click on “Update Your Profile” from the red navigation toolbar.  Be sure to click the "Submit" button upon completion. 

NOTES:

• The pdf version of the Membership Directory is published annually.  For the most up-to-date information, please use the online search option.
• The ASHI Accredited Laboratories is listed separately in the Lab Center section of the web site under Accreditation.

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Committee Spotlight: The ASHI Proficiency Testing (PT) Program

Those of you who aren’t directly involved in entering ASHI PT Survey results or, in  reading the Performance and Summary Reports may not be aware of the incredible number of improvements that have been made during the last 2 years as ASHI has changed to an entirely in-house system. 

The ASHI PT Program offers surveys designed to assess laboratory performance in HLA typing by serological, low resolution DNA, and/or high resolution DNA   methods: the detection of HLA B27 by any method; HLA antibody screening and/or specificity identification and crossmatching by different methods; and monitoring engraftment after allogeneic HPC transplant.   Some of the most significant improvements, thanks in large part to the efforts of our PT Program’s Data Manager, Danny Youngs, are the following:

• All results entry and Summary and Performance Reports for 2010 and 2011 use the new WHO HLA nomenclature.
• The entry of results is more user friendly– all results can be entered at once for each sample or partially entered and saved for additional entry later.  All results for the B27 and EMO Surveys can be entered on a single “page”.
• Analyses of consensus for antibody specificities for all “regions” are now combined.  (All regions receive the same sera for analysis but separate analyses in the past caused some discrepancies between regions in consensus results.)
• The selection of “serology equivalent” results for low resolution molecular no longer requires a separate field entry (e.g., B*(60)40 or B*(61)40 are now possible low resolution molecular entries).
• The collected information about cell quality for HLA Typing and Crossmatching are now included in the Summary Reports for Surveys HT and AC, respectively.
• Types reported for any loci are included in the combined analyte grades, even if only results for a single locus or single allele are reported (as might occur for labs only doing disease or drug hypersensitivity risk testing).
• The PT Vendor continues to provide samples for HLA Typing with substantial allele variety from ethnically diverse populations.  Three new HLA-alleles have been identified in the last two years: B*27:51, A*03:71 and another new A*03 allele. This new A*03 allele has an exon 4 substitution at nucleotide position 643 that changed codon 191 from histidine to aspartic acid.  In addition, one of the samples sent in 2010 surprised laboratories by having a DRB1*15 haplotype without a DRB5 gene and some alleles previously thought to be “rare” have been seen more than once (e.g., A*23:17).  The expert evaluation of results enhances the educational value of these surveys.
• Performance Reports and Summary Reports for each survey are available at the same time, allowing survey participants immediate access to explanatory comments about the unusual features of any of the samples tested. 
• Typing for Cells sent for crossmatching now includes DQA1 types in addition to A, B, C, DRB1, DRB3/4/5, DQB1, and DPB1 types.   This assists labs in interpreting the PT Crossmatch results in ways that are similar to the way they can interpret clinical crossmatch results.
• Laboratories accredited by ASHI are now able to request that their Survey Performance Reports be sent directly to the ASHI Accreditation Review Board.  (Laboratories accredited by the CAP continue to be able to request that their Performance Reports be sent to the CAP.)   This new option for ASHI accredited laboratories will reduce considerably the number of documents laboratories will need to submit with their ASHI re-accreditation applications.
• The deadlines for submission of results were extended to 11:59 PM Pacific Time on the Survey Due dates to accommodate west coast laboratories with last-minute entries.

There have been other improvements as well, many of which were made in response to user comments. The committee is happy to receive questions and suggestions from PT users.  For further questions about the ASHI PT Surveys or, to provide suggestions please contact Cecilia Blair ( or 856-642-4411).

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Major Changes To Molecular CPT Coding For 2012

As most of you are aware, the current CPT codes for molecular testing, including HLA, are composed of a complex list of "stacking" codes that must be used to build the charge for any non-microbiology molecular test.  This has proved to be cumbersome and confusing for those creating the charge and has not been informative for the payors who are billed for this charge, despite the use of modifiers to identify the gene tested.  

In December of 2009, the AMA CPT Editorial Panel convened a workgroup to propose solutions to issues for coding molecular assays in cancer, genetics and histocompatibility.   ASHI as part of the original workgroup has participated actively for the last year and a half in the development of new codes for these molecular assays.   In March of this year (in an unprecedented move) the AMA CPT Editorial Panel released a draft of the molecular testing codes that had been approved for 2012 and asked for public comment.   The link to this information was provided at that time in a blast email from ASHI Headquarters.    The link and a brief overview provided by the AMA is given below.  ASHI continues to participate in the workgroup as it responds to the public comment and works on other issues. 

For more information about the workgroup process and what it will mean for the coding of molecular testing, a link is provided to an article written by Mark Synovec, one of the co-chairs of the workgroup, and published in CAP Today. 
http://digital.olivesoftware.com/Olive/ODE/CapToday/Default.aspx?href=CAP/2011/04/01&pageno=5&view=document

Because of the extensive nature of the changes, there will be a workshop at the ASHI Annual Meeting that will provide information on how these codes should be used.  The presentation will be given by ASHI members who participated in the workgroup.  There will also be time for questions and answers at the end of the workshop.

FROM THE AMA
Following is a summary of the announcement that is located on the CPT web site at:
http://www.ama-assn.org/ama1/pub/upload/mm/362/request-for-molecular-pathology-code-review-and-feedback.pdf (ed.note:  this was included in the March 2011 blast email from ASHI)
 
In December 2009, the AMA CPT Editorial Panel convened a workgroup to propose solutions to issues for coding molecular assays in cancer, genetics and histocompatibility.

• The output of that workgroup, illustrated in the test descriptors provided and available in this release for review and comment to interested stakeholders before publication for CPT 2012, represents the major changes to molecular assay reporting that are coming next year.
• These changes do NOT affect molecular microbiology tests or most cytogenetic assays.
• The most commonly-performed tests (Tier 1) will have a test (analyte) specific CPT code.
• Less commonly-performed tests (Tier 2) have been assigned to 9 resource level codes determined by level of resources required for their performance and interpretation.
• Analytes/tests that have new codes assigned and are listed in Tiers 1 and 2 MUST be coded using the most specific CPT code available and NOT with 'stacking codes' (83890-83914).
• CPT 'stacking codes' (83890-83914) will remain available to report tests in 2012 for tests that have not been assigned analyte-specific or resource level codes. 'Stacking codes' will be retired at the conclusion of this initiative (most likely 2013).
• This process is ongoing and there will be significant additional analytes included in 2013

Access to the proposed descriptors is necessary to ensure that a broad base of review is performed by those who will be required to report these services.
Any requests for revision should be sent to AMA staff by April 15th at .

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Opportunity for International Collaboration and Visibility: Call for Clinical Trial Contributions

ASHI is a member of the Federation of Clinical Immunology Societies (FOCIS), which has created an opportunity for collaboration with their member societies in building an interdisciplinary clinical trial listing in the new ePublication, Translational Immunology Update. The section will include phase 1 and 2 studies using novel immunotherapeutics or standard immunotherapeutics in new diseases or new ways.  The trials will be formatted in a table with key variables including the drug name, disease, N, overall study design, primary outcome variable and result.  The goal is for readers to have a better understanding of the application of clinical immunology outside of their field. To participate, submit trials of which you are aware to http://translationalimmunology.pbworks.com/Clinical-Trial-Contributions. Please note, you will need to request access to the contribution site, which will be granted within 24 business hours. 2011 publication deadlines: June 1, August 1, October 1, December 1.

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ASHI At FOCIS 2011

The Federation of Clinical Immunology Societies (FOCIS) is the leading collaborative forum for education, research and networking across the broad field of clinical immunology. ASHI has partnered with the American Society for Transplantation (AST) and the Association of Medical Laboratory Immunologists (AMLI) to sponsor two exciting Member Society Symposia at FOCIS 2011 on Thursday, June 23, 2011 at the Marriott Wardman Park Hotel, Washington, D.C.  ABHI has approved the ASHI/AMLI symposium for three (3) hours or .45 CECs. Please join us as we explore the various immunologic issues that bind our community.

For more information on FOCIS 2011:
June 23, 2011 Washington D.C.
http://www.focisnet.org/FOCIS/index.php?option=com_content&task=view&id=120&Itemid=152

ASHI/AST co-sponsored symposium:
June 23, 2011 8:00 am-12:15 pm.
Tolerogenic B Cells and B cell Signatures in Transplant Rejection and Tolerance. 
http://www.focisnet.org/FOCIS/images/focis2011/ast-ashi agenda final-3.8.pdf
 
ASHI/AMLI co-sponsored symposium:
June 23, 2011 12:45 pm-4:15 pm.
Recent Progress in Elucidating the Role of Host Genetics and Immune Responses in Transplantation and Infectious Disease: Implications for the Clinical Immunology/HLA Laboratory. 
http://www.focisnet.org/FOCIS/images/focis2011/amli-ashi agenda-4.14.11.pdf
Note: This symposium has been approved for three (3) hours or .45 ABHI CECs.
 
Additional FOCIS Educational Offerings: 
http://www.focisnet.org/FOCIS/index.php?option=com_content&task=view&id=17&Itemid=30

To learn more about FOCIS and membership:
http://www.focisnet.org/FOCIS/index.php

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IDAWG Survey

ASHI IDAWG 16th IHIW Survey of Immunogenetic Data Management and Analysis Practices

ASHI is collaborating with the Immunogenomics Data Analysis Working Group (IDAWG) to survey the histocompatibility and immunogenetics community on current data management and analysis practices.

The IDAWG is an international collaboration of histocompatibility and immunogenetics investigators with the goal of making immunogenetic data more useful across studies and between research groups. Toward this end, the IDAWG has initiated an International Histocompatibility and Immunogenetics Workshop (IHIW) project for the development of new data-management tools and documentation standards.

This IHIW project will be informed by the responses to the ASHI IDAWG 16th IHIW Survey of Immunogenetic Data Management and Analysis Practices.  This is a broad survey of the approaches for HLA and KIR data management and transmission, HLA ambiguity management and resolution, and primary data analysis as currently applied by the community.

The survey is available at http://www.surveymonkey.com/s/IDAWG, and should take approximately 15 minutes to complete. All members of the histocompatibility and immunogenetics community are invited to take the survey.

The survey can be submitted anonymously, and although survey participants are invited to take part in the larger IDAWG Workshop project, information specific to individual laboratories will be kept confidential; individual laboratories will not be identified without providing consent.

When survey participants have indicated their interest, the survey will be followed-up with synthetic datasets for the purpose of demonstrating HLA ambiguity resolution and primary data-analysis practices.

More information about this project can be found at http://immunogenomics.org/workshop.html. Please direct any questions or comments about the survey to .

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This E-Newsletter is sponsored by:

 

 

 

Life Technologies Initiates Clinical Trials Leading to 510(k) Submission of a Class I and Class II HLA Sequence-Based Typing Solution

Life Technologies announced on March 21, 2011 in a company press release that the company is entering into clinical trials to prove the safety and effectiveness of their DNA sequence-based typing platform for analysis of the HLA system for the purpose of submission for 510(k) clearance. 

The company’s exhibit at the American Association for Clinical Chemistry (AACC) Annual Meeting in Atlanta, Georgia July 24-28th will include components of the HLA workflow that are planned for submission.  Featured products include the 3500 Dx Genetic Analyzer system, SeCore® kits and uTYPE® analysis software. Company representatives will be available at the exhibit to discuss the HLA workflow in detail.  To read the press release click here.

Other Life Technologies HLA events include a luncheon on June 17th during the ASHI Regional Meeting in Seattle.  The event will feature customer discussions about first-hand research experiences with the company’s HLA-related products including SeCore® SBT kits, uTYPE® Analysis Software, AllSet™ Gold SSP kits, and the PlexMark® BioMarker Panel.  Please contact Bill Yang () to attend.

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In the Groove

Welcome to 'In the Groove' an ASHI e-newsletter publication.  The e-newsletter contains timely and important information for professionals working in histocompatibility, immunogenetics and transplantation. This e-newsletter is intended to supplement the ASHI Quarterly by providing information that just can’t wait until the next issue.

The e-newsletters include updates from ASHI committees, proposals out for public comment from regulatory agencies, news from other associated societies, surveys, notices about ASHI meetings and other meetings of interest to our members, tables of contents from recent issues of Human Immunology, and news from our sponsoring vendors. The electronic format provides the opportunity to read information on the go from portable devices and the ability to click directly to the items that interest you most.

If you have any comments or suggestions for future e-newsletters, please send them to Melissa Roberts via email:

2011 - 4th Edition (December 2011)
2011 - 3rd Edition (September 2011)
2011 - 2nd Edition (June 2011)
2011 - 1st Edition (March 2011)

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E-Newsletter 1st Edition

March 2011

A Message from the President Elect, Amy Hahn

Welcome to the inaugural edition of the ASHI e-newsletter! We’re starting small, but future e-newsletters will be full of the timely and important information you need as a professional working in histocompatibility, immunogenetics and transplantation. This e-newsletter isn’t intended to take the place of the ASHI Quarterly, rather it will supplement it by bringing you information that just can’t wait until the next issue. The items you see in the e-newsletter will include news from ASHI committees, proposals out for public comment from regulatory agencies, news from other associated societies, surveys, notices about ASHI meetings and other meetings of interest to our members, tables of contents from recent issues of Human Immunology, and news from our sponsoring vendors. By having this information in electronic format, you’ll be able to click right through to the items that interest you most. We hope that you’ll find this e-newsletter to be a useful and educational benefit of being a member of ASHI. If you have any comments or suggestions for future e-newsletters, please send them to Melissa Roberts via email:

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Save the Date – ASHI Regional Workshops

The ASHI Education Committee cordially invites you to attend this year’s ASHI Regional Workshops in Chicago and Seattle. We are honored to have our President, Dr. Geoffrey Land, provide a Keynote Address on volunteerism at our Thursday evening reception. Make plans to arrive early   - you don’t want to miss out on this opportunity. The faculty is eager to share their expertise and experience with the attendees. Our goal is to provide an interactive, educational atmosphere that will provide ASHI members,  from the novice to experienced bench technologists and supervisors, with some necessary theory and practical application in the laboratory.  For more information or to download the regional brochure, click here.

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Changes to CPT Appendix I Effective January 1, 2011

We would like to bring to your attention a change that was made in the AMA 2011 CPT Coding Manual Appendix I.  (see page 431 of the 2011 Standard Edition of the CPT Coding Manual. )

The Histocompatibility/Blood Typing/Identity/Microsatellite section has been changed for 2011.  Modifiers are now available for all HLA loci.  
•  Modifier 4E, previously designated DR, has been changed to 'DRB All' and should only be used for a combined low resolution DRB1/3/4/5 typing.
•  Modifiers 4F and 4G, previously designated DQ and DP, have been changed so that they now code for DQB1 and DPB1 respectively. 
•  HLA D has been deleted. 
•  Unique modifiers for DRB1, DRB3, DRB4, DRB5, DQA1, and DPA1 have been added. 

Labs that are using the genetic testing code modifiers from Appendix I should make the appropriate changes to their CPT codes. 

From CPT codes, Appendix I, Genetic Testing Code Modifiers

4A HLA-A*
4B HLA-B*
4C HLA-C*
4E HLA DRB all (use for typing for DR that includes DRB1/3/4/5 in the same kit or same test.)
4P HLA-DRB1*
4Q HLA-DRB3*
4R HLA-DRB4*
4S HLA-DRB5*
4T HLA-DQA1*
4F HLA-DQB1*
4U HLA-DPA1*
4G HLA-DPB1*

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 AST Establishes Transplant Diagnostics Community of Practice

The American Society of Transplantation is excited to announce the launch of the Transplant Diagnostics Community of Practice (Tx Dx COP).  This community of practice is open to all transplant professionals involved in diagnostics, including transplant pathologists, immunogeneticists, and other laboratory medicine specialists.  The COP serves as a forum to network and share ideas, expertise, and knowledge to achieve shared goals.
 
An executive committee was formed to represent the diverse group of transplant diagnostics, and consists of a Chair, Co-Chair, and 3-4 Members-at-Large.  Overall goals of the Tx Dx COP are to:

•  provide a mechanism by which physicians and medical professionals involved in transplantation diagnostics can network

•  serve as an authoritative voice on matters related to diagnostics in transplantation for the AST, as well as other medical organizations and governmental institutions

•  create and promote the spread of best practices through the communication, implementation and maintenance of diagnostic and quality assurance standards;

•  develop educational resources for medical professionals and patients involved with organ transplantation

•  Provide strong networking opportunities and develop professional skills by sharing knowledge and experience with preexisting organizations

 
Annually, the COP meets face-to-face at the American Transplant Congress (ATC).  At this meeting, members of the COP can network, discuss future initiatives and volunteer for projects. 
 
Membership is open to anyone involved in the science and practice of transplantation. Non-AST members can participate for a one-year trial. After this period, non-members must join AST to continue participation in the COP.
 
If you are interested in becoming a member of the AST Transplant Diagnostics Community of Practice, please use the online form to submit your professional interest details and contact information. For more information visit, the AST Tx Dx COP website at http://www.a-s-t.org/cop/transplant-diagnostic-cop.

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ASHI sponsors Symposia at FOCIS 2011

Please join ASHI at the upcoming FOCIS 2011 for the satellite symposia on June 23rd in Washington, DC.  For details about FOCIS or the ASHI sponsored event please visit FOCIS.

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ASHI’s comments for the MEDCAC on “The Impact of ESA Use in Renal Transplantation” and “The Impact of Pre-Transplant Red Blood Cell (RBC) Transfusions in Renal Allograft Rejection.”

 

The Medicare Evidence Development & Coverage Advisory Committee (MEDCAC) held a January 19, 2011 hearing on “The Impact of Erythropoiesis Stimulating Agents (ESA) on Renal Transplant Survival.” Dr. Susie Leffell presented comments on ASHI’s behalf. To read her testimony, click here.

Following this hearing there was a February 3, 2011 deadline for comments on the technology assessment portion of “The Impact of Pre-Transplant Red Blood Cell (RBC) Transfusions in Renal Allograft Rejection.” The ASHI leadership submitted comments which will be reviewed and posted by May 3, 2011 at http://www.ahrq.gov/clinic/techix.htm. To read these comments now, click here.

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Mexico City Workshops

IMMUNOGENETICS:
Monday, July 25 – Friday, July 29

MOLECULAR GENETICS:
Monday, August 1 – Friday, August 5

For more information, click here click here.

For information about the agenda, click here.

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Membership Connection

Get connected with Facebook, Linkedin, and Twitter for the latest ASHI announcements and discussions regarding the association, education and events, and industry related topics. Don’t forget to check out the Eblasts Archives page for the latest e-mail blasts and the News Archives for the latests news postings to ASHI.

 

Facebook
http://www.facebook.com/pages/American-Society-for-Histocompatibility-Immunogenetics/147211865310535

 

Linkedin
http://www.linkedin.com/groupRegistration?gid=1878945&sharedKey=22ABC2119A72

 

Twitter
http://twitter.com/ASHI_HLA

 

News Archives
http://www.ashi-hla.org/news

 

Eblast Archives
http://www.ashi-hla.org/news/eblasts

 

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Home > ARB Release Form

ARB Release Form

Click here if the download does not automatically start.

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Shared Resources

Documents

Summary of the ASHI presentation at the FDA meeting on LDTs(Adobe PDF)

 

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Home > taking1

taking1

ccc

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Home > Forms

Forms

Application Form For Continuing Certification (89KB, PDF)

Application Form for Provider Status (582KB, PDF)

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Annual Dues

The following is the current schedule for the ABHI's annual dues. Annual Dues for CHA, CHT, and CHS $45 Annual Dues for Histocompatibility Director $150

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Provider Fee Schedule

The ABHI approved provider fee schedule is provided in the table below.

Category	Provider	Fees or Corporate/Vendor Sponsorships	Program Hours	Fee
A	Laboratory/Organization/Society	No attendee registration fees, membership fees, or sponsorships collected	15 or fewer hrs per year	$50
B			More than 15 hrs per year	$100
C	Laboratory/Organization/Society	Program does collect registration fees, membership fees, or sponsorships	15 or fewer hrs per event	$175
D			More than 15 hrs per event	$350
E	Corporate, Commercial, Vendor	Sponsorship	10 or fewer hrs per program	$290
F			More than 10 hrs per program	$400
G	Organization/Society, Corporate, Commercial or Vendor	Not applicable	Offering same program at multiple venues	$600

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Taking the Exam

Administering or Taking the Examination
The examination will be by computer at an AMP Assessment Center . Candidates do not need any prior computer experience or typing skills to take the examination. On the day of the examination, report to the Assessment Center no later than the scheduled testing time. Look for signs indicating AMP Assessment Center Check-in. A CANDIDATE WHO ARRIVES MORE THAN 15 MINUTES AFTER THE SCHEDULED TESTING TIME WILL NOT BE ADMITTED.

Identification
To gain admission to the Assessment Center , a candidate needs to present two forms of identification, one with a current photograph. Both forms of identification must be current and include the candidate's current name and signature. The candidate will be required to sign a roster for verification of identity. Acceptable forms of photo identification include a current driver's license with photograph, a current state identification card with photograph, a current passport, or a current military identification card with photograph. Employment ID cards, student ID cards and any type of temporary identification are NOT acceptable as the primary form of identification. CANDIDATES MUST HAVE PROPER IDENTIFICATION TO GAIN ADMISSION TO THE ASSESSMENT CENTER . Failure to provide appropriate identification at the time of the examination is considered a missed appointment. There will be no refund of the testing fee.

Rules for Examination
Security
AMP maintains test administration and test security standards that are designed to assure that all candidates are provided the same opportunity to demonstrate their abilities. The Assessment Center is continuously monitored by audio and video surveillance equipment for security purposes.

The following security procedures apply during the examination: Examinations are proprietary. No cameras, notes, tape recorders, personal digital assistants (PDAs), pagers or cellular phones are allowed in the testing room.

No programmable calculators are permitted. Only silent, hand-held, solar-or battery-operated calculators without paper tape-printing capabilities or alphabetic keypads, may be used. Financial calculators are allowed if they meet these specifications. Calculator malfunction during a test does not constitute grounds for challenging test scores or requesting additional test time. No guests, visitors or family members are allowed in the testing room or reception areas. No personal items, valuables, or weapons should be brought to the Assessment Center . Only keys and wallets may be taken into the testing room. AMP is not responsible for items left in the reception area.

Examination Restrictions
No personal belongings will be allowed in the Assessment Center . Pencils will be provided during check-in. The candidate will be provided with scratch paper to use during the examination, which must be returned to the supervisor at the completion of testing, or the candidate will not receive a score report. No documents or notes of any kind may be removed from the examination room. No questions concerning the content of the examination may be asked during the examination.

Eating, drinking or smoking will not be permitted in the Assessment Center . The candidate may take a break during the examination, but will not be allowed additional time to make up for time lost during breaks.

Misconduct
Individuals who engage in any of the following conduct may be dismissed from the examination, their scores will not be reported and examination fees will not be refunded. Examples of misconduct are when a candidate: creates a disturbance, is abusive, or otherwise uncooperative; uses electronic communications equipment such as pagers, cellular phones, PDAs; gives or receives help or is suspected of doing so; attempts to record examination questions or make notes; attempts to take the examination for someone else; or is observed with notes, books or other aids.

Copyrighted Examination Questions
All examination questions are the copyrighted property of ABHI. It is forbidden under federal copyright law to copy, reproduce, record, distribute or display these examination questions by any means, in whole or in part. Doing so may subject the candidate to severe civil and criminal penalties.

Practice Test
After the candidate's identification has been confirmed, he/she will be directed to a testing carrel. The candidate will be instructed on-screen to enter their Social Security number, and instructed on how to take their photograph which will remain on screen throughout the testing session. This photograph will also print on the score report.

Prior to attempting the examination, the candidate will be given the opportunity to practice taking a test using the computer. The time used for this practice test is NOT counted as part of the examination time or score. Once the candidate is comfortable with the computer testing process, he/she may quit the practice session and begin the timed examination.

Timed Examination
Following the practice test, the actual examination will begin. Before beginning, instructions for taking the examination are provided on-screen.

The computer monitors the time spent on the examination. The candidate will have 3.5 hours to complete the CHA, CHS, and CHT examinations and 5 hours to complete the Labratory Director examination. The examination will terminate if testing exceeds the time allowed. Click on the "Time" box in the lower right portion of the screen or select the Time key to monitor testing time. A digital clock indicates the time remaining to complete the examination. The Time feature may be turned off during the examination.

Only one examination question is presented at a time. The question number appears in the lower right portion of the screen. Choices of answers to the examination questions are identified as A, B, C, or D. The candidate must indicate his/her choice by either typing in the letter in the response box in the lower left portion of the computer screen or clicking on the option using the mouse. To change an answer, enter a different option by pressing the A, B, C, or D key or by clicking on the option using the mouse. The candidate may change his/her answer as many times as he/she wishes during the testing time limit.

To move to the next question, click on the forward arrow (>) in the lower right portion of the screen or select the NEXT key. This action will move the candidate forward through the examination question by question. To review any question, click the backward arrow (<) or use the left arrow key to move backward through the examination.

An examination question may be left unanswered for return later in the testing session. Questions may also be bookmarked for later review by using the mouse and clicking in the blank square to the right of the Time button. Click on the hand icon or select the NEXT key to advance to the next unanswered or bookmarked question on the examination. To identify all unanswered and bookmarked questions, repeatedly click on the hand icon or press the NEXT key. When the examination is completed, the number of examination items answered is reported. If not all questions have been answered and there is time remaining, return to the examination and answer those questions. Be sure to provide an answer for each examination question before ending the examination. There is no penalty for guessing.

Candidate Comments
During the examination, online comments may be provided for any question by clicking on the button displaying an exclamation point (!) to the left of the Time button. This opens a dialogue box where comments may be entered. Comments will be reviewed, but individual responses will not be provided.

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Statement of Competence

Statements of Competence for Histocompatibility Personnel (Adobe PDF)

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Applying

Submitting an application for the examination s
Complete the paper application included in the Candidate Handbook and mail it with the appropriate fee to ABHI, P.O. Box 19173 , Lenexa , Kansas 66285 -9173.  ABHI overnight address is: 18000 W. 105th Street, Olathe, Kansas  66061

The application is processed and a confirmation notice of eligibility is sent to the candidate within approximately two weeks. If a confirmation notice is not received within three weeks, contact the ABHI at 913/895-4602., ext. 4778.

Scheduling the examination and Administration Process
Once the candidate receives their confirmation notice he/she should immediately schedule an examination appointment at their convenience during the month in which they have applied. The confirmation notice contains a web address and toll-free telephone number for the candidate to contact AMP; ABHI’s testing agency. Appointments can also be scheduled online 24 hours a day, seven days a week at www.goAMP.com . The toll-free line is answered from 7:00 a.m. to 7:00 p.m. (Central Time) Monday through Thursday and 7:00 a.m. to 5:00 p.m. (Central Time) on Friday. The candidate must be prepared to confirm a date and location for testing and to provide her/his Social Security number as a unique identification number.

A candidate's eligibility and acceptance of the application is valid only during March or September. A candidate who fails to schedule an appointment for examination by the end of either month's eligibility deadline must re-submit a complete application including examination fee to schedule an examination appointment.

The ABHI examination is administered via computer at over 150 Applied Measurement Professionals (AMP) Assessment Centers geographically distributed throughout the United States and Canada . The international assessment centers that are available can be viewed at: http://www.goamp.com/AMP/Internationallocations.htm

The examinations are administered by appointment only Monday through Friday at 9:00 a.m. or 1:30 p.m. during the months of March and September . Individuals are scheduled on a first-come, first-served basis. Refer to the chart below.

Note: Examinations will not be offered on Labor Day.

If the candidate contacts AMP by 3:00 p.m. Central Time on...	Depending on availability, an examination may be scheduled beginning...
Monday	Thursday
Tuesday	Friday
Wednesday	Monday
Thursday	Tuesday
Friday	Wednesday

The candidate must contact AMP to schedule an appointment and will be given the specific time to report to the center. No admission ticket will be issued; therefore, the specified examination location, date and time should be noted. Candidates who arrive at the Assessment Center later than 15 minutes from the scheduled appointment time will not be admitted. Unscheduled candidates (walk-ins) will not be admitted to the Assessment Center .

ABHI reserves the right to verify information supplied by the candidate. An application is considered complete only if all requested information is complete and accurate; if the candidate is eligible for the examination; and if fees are submitted. Examination fees for ineligible applications will be refunded minus a $50 processing fee.

Computerized Version Appointment Changes
A candidate may reschedule ONE appointment for the computerized version of the examination at no charge by calling AMP at 888/519-9901 at least four business days prior to the scheduled testing session. (See table below.)

If an examination is scheduled on...	The candidate must call AMP by 3:00 p.m. Central Time to change his/her reservation by the…
Monday	previous Tuesday
Tuesday	previous Wednesday
Wednesday	previous Thursday
Thursday	previous Friday
Friday	previous Monday

A candidate who wishes to reschedule their examination but fails to contact AMP at least four business days prior to the scheduled testing session forfeits the application and all fees paid to take the examination. A complete application and examination fee are required to reapply for examination.

A candidate who cancels their examination after confirmation of eligibility forfeits the application and all fees paid to take the examination. A complete application and examination fee are required to reapply for examination. If a candidate must cancel an examination appointment or would like to request a refund due to a medical emergency the candidate must submit the request in writing accompanied by official written notification from attending physician to the ABHI Executive Office.

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Exam Fees

The following is the new schedule for the ABHI's examination application fees January 1, 2009. CHA and CHT Examination Application Fees $195 CHS Examination Application Fee $225 Histocompatibility Laboratory Director Examination Application Fee $890

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Exam Schedule

The ABHI Certification Examination for Associates, Technologists and Specialists will be offered in March and September . The examination will be administered by computer, and offered on any weekday during the months of March and September at over 150 assessment centers in the United States. There will be no specific pre-scheduled testing dates. Once a candidate’s eligibility is confirmed he/she will receive notice from the testing agency including instructions on how to schedule their examination appointment during March and September.  Test time for the Associates, Technologists and Specialists has been extended an additional 30 minutes allowing 3.5 hours to testing time.

The application deadlines will be January 1 and June 1 respectively for the CHA, CHS and CHT examinations.

The Histocompatibility Laboratory Director examination will be offered in September of each year. The application deadline will be June 1.

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Continuing Education

Only CHAs, CHSs, and CHTs who are due to recertify in the current year will be required to submit the completed application for Continuing Certification and documentation of CECs.  ABHI will no longer be reviewing every individual's CE activity each year. ABHI will review the CE Activity of only those individuals whose certification will be expiring at the end of the current year.  The application and documentation of activity will now be due to the ABHI Executive office by November 15 of the recertifying year.  All other ABHI certificants who are not within their recertifying year will be required to submit annual dues, notices will be released in December. 

Accepted CE Activities

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Provider Fee Schedule

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Examinations

 

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Candidate Handbook

ABHI Candidate Handbook

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Related Links

Links to Resources and Useful Information

We hope you will use this collection of links for accessing resources and useful information. If you know of any useful resources related to our field, please send your suggestions . While we strive to check the validity of the links, web sites come and go, or move quite frequently. If any link operates incorrectly, please let us know so that it can be corrected.

Clinical and Transplantation
Government and Regulations
Immunology and Societies
Journals and Libraries
MHC and HLA
Molecular Biology and Genetics

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Clinical and Transplantation

clinical information and transplant organizations

• ABO Mismatch Reporting Center - accumulates and analyses available data with the aim to reach a deeper insight and to bring together those interested in ABO disparate transplantation. Great bibliography on ABO-mismatched transplants.
• AllergyImmunoLinx.com/Surgery/Transplantation Articles - a free, fast, and easy-to-use Web site designed to keep medical professionals informed of daily clinical developments. Each morning, the top Allergy and Immunology articles in surgery/transplantation and other specialties are aggregated from hundreds of premier medical journals.
• American Society of Transplantation
• Anthony Nolan Bone Marrow Trust [UK]
• Bone Marrow Donors Worldwide [The Netherlands]
• Bone Marrow Transplant Topics @ http://www.bmtinfo.org
• The Immune Tolerance Network (ITN) is an international clinical research consortium founded by the National Institute of Allergy and Infectious Diseases (NIAID), with additional support from the Juvenile Diabetes Research Foundation (JDRF), whose mission is to accelerate the clinical development of immune tolerance therapies. The ITN develops, implements, and conducts trials of novel immune tolerance therapies in type 1 diabetes, autoimmune diseases, solid organ and islet transplantation, and allergy and asthma. ITN trials look beyond the traditional endpoints of safety and efficacy, building into each trial a complementary set of genetic, cellular, and immunological studies that explore the underlying mechanisms of tolerance and disease.
• International Society for Hemotherapy & Graft Engineering (ISHAGE)
• International Pediatric Transplant Association - The International Pediatric Transplant Association (IPTA) is a professional organization of individuals in the field of pediatric transplantation.
• Medical Matrix-Guide to Internet Clinical Medicine Resources
• MedScape - a robust and integrated multi-specialty medical information and education tool. You may choose a personal Medscape home page from an assortment of specialty sites including Transplantation, primary care medicine sites, and nonclinical sites such as "Money & Medicine" or "Humor & Medicine." Requires a simple, one time, free registration. Excellent source for review of current medical literature, access to electronic journals, and CE programs (mostly free).
• National Marrow Donor Program (NMDP)
• NIAID Plan for Research on Immune Tolerance: Clinical Trials of Transplant Tolerance
• SEOPF
• TransplantHealth is a patient-oriented web site designed to provide transplant patients with information during the various stages of transplantation
• Transplant Pathology Internet Services (TPIS) at the University of Pittsburgh - a great source of transplant-related information and educational resources -- download the updated HLA Matchmaker Software by Rene Duquesnoy, Ph.D.
• Transweb: An Internet Resource Devoted to Transplantation and Donation
• UNOS

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Government and Regulations

CLIA, HCFA, OSHA, MSDS's, Federal Register and more

• Centers for Medicare and Medicaid Services (CMS, formerly HCFA)
• Federal Register - search for rules and regulations here.
• Analyte Specific Reagents - Final Rule (PDF). Requires free Acrobat Reader software.
• HIPAA Privacy Regulation Guidance - guidance on the final HIPAA regulations issued by HHS on 7/6/2001; full compliance by health care organizations, including labs, is required by 7/14/2003.
• MSDS Database at Vermont SIRI
• OSHA Information
• Cahaba Government Benefits Administrator - administers Medicare health insurance for the Centers for Medicare & Medicaid Services (CMS).
• Thomas: Legislative information (Library of Congress)

More Information on the Analyte Specific Reagent Rule:

• ASR Fact Sheet from the College of American Pathologists (CAP)
• Questions & Answers from the College of American Pathologists (CAP)
• "ASR: FDA Issues Final Rule" - an article by Jeffrey N Gibbs published in IVD Magazine, January 1998

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Immunology and Societies

Immunology resources and links to related organizations

• American Association of Blood Banks (AABB)
• American Association of Immunologists
• The Antibody Resource Page
• AMLI - Association of Medical Laboratory Immunologists
• ASCB - American Society for Cell Biology - this site has excellent information on public policy issues, such as discussions on human cloning and its impact on the practice of transplantation.
• ASEATTA - The Australasian and South East Asian, Tissue Typing Assoc. Inc. It has members in Australia, New Zealand, Hong Kong, Thailand, India, Singapore, Mongolia, Malaysia, The Phillipines, South Africa, Indonesia, Japan, the USA and New Guinea. [Australia]
• British Society for Histocompatibility and Immunogenetics (BSHI) [UK]
• Clinical Cytometry Society
• More about Corticosteroids [CH]
• Cyclosporin A images [UK]
• Cytokines Online Pathfinder Encyclopedia [DE]
• European Federation for Immunogenetics (EFI)
• Federation of Clinical Immunology Societies (FOCIS) - ASHI is now a participating society! See meeting announcement below.
• Immune Responses lecture guide
• Molecular Immunology - a great collection of immunology information and a wealth of links
• Images of Immunoglobulin Structures [UK]
• International Society for Analytical Cytology (ISAC)
• The Lymphatic System and Immunity
• Facts about Leukocytes and Mast Cells [CH]
• How Lymphocytes Produce Antibody - Cells Alive

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Journals and Libraries

tables of contents, abstracts and full-text articles; Medline

• Allergy and Clinical Immunology International , official journal of the World Allergy Organization, includes reviews and original articles on both clinical and research topics, association and meeting news, and a regular website review column. Currently, volumes from 1995 through the present are available online in full-text form free of charge.
• ASM Journals Online
• Blood & Marrow Transplant Newsletter is a not-for-profit organization that provides publications and support services to bone marrow, peripheral blood stem cell, and cord blood transplant patients and survivors.
• Clinical and Applied Immunology Reviews - table of contents
• Clinical and Experimental Allergy - tables of contents
• Clinical and Experimental Immunology - tables of contents
• Elsevier: Table of Contents of 900 journals including Human Immunology You can also sign up for the Table of Contents to be emailed to you directly each month. [The Netherlands]
• Entrez (Medline-Molecular Biology)
• European Journal of Immunogenetics - tables of contents
• Experimental and Clinical Immunogenetics - tables of contents
• Genes and Immunity - tables of contents
• HighWire Press - a service of Stanford University Libraries, is claimed to be the Earth's largest free full-text science archives
• Treatment Strategies - Hematology - a print and on-line eBook publication that provides the readership with a collection of comprehensive and thought provoking articles from the most respected key opinion leaders, leading doctors and authorities in the field.

Human Immunology Online! - tables of contents and abstracts; full-text and PDF format are available to ASHI members for downloading

• Immunity
• Immunogenetics - tables of contents and abstracts; full-text is available in PDF format for registered users
• Immunology - tables of contents
• International Digital Electronic Access Library - IDEAL is a developmental project of Academic Press, aiming to greatly expand and improve access to a large number of scientific journals. Journal tables of contents and abstracts are freely available to anyone (guest login required). Authorized Users at sites within the licensed consortia of the project can view, search, print, and download complete articles in the Acrobat format.
• Journal of Biological Chemistry
• Journal of Immunology
• Journal of Molecular Biology [UK]
• Journal of Molecular Diagnostics
• Leukemia Insights Newsletter from the M.D. Anderson Cancer Center - a source of information on Bone Marrow transplantation.
• National Library of Medicine
• Nature
• Nature Immunology - access to first two issues free; register for free access to tables of contents
• New England Journal of Medicine
• Reviews in Immunogenetics [DK] - tables of contents and sample full-text issue
• Science
• "The Scientist" On line
• Seminars in Immunology - tables of contents and abstracts
• Search Medline free through the National Library of Medicine:
  • PubMed
  • Medline provides free access to MEDLINE, sets of related articles pre-computed for each article cited in MEDLINE, and linkages to publishers' sites for full-text journals. At least 24 journals available, some by subscription only.
  • MEDLINEplus has extensive information from the National Institutes of Health and other trusted sources on over 500 diseases and conditions. There are also lists of hospitals and physicians, a medical encyclopedia and dictionaries, health information in Spanish, extensive information on prescription and nonprescription drugs, current health news, and links to thousands of clinical trials.
• Scandinavian Journal of Immunology - tables of contents
• Tissue Antigens [Denmark]
• Transplantation
• Virtual Library-Immunology

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MHC and HLA

immunogenetics, MHC, HLA and disease association resources

• Allele Frequencies in Worldwide Populations
• Birkbeck College XRay Crystalography images
• HLA Class I and Class II Sequence Data at the Anthony Nolan Research Institute [UK]
• HLA Gene and Haplotype Frequencies in the North American Population : The National Marrow Donor Program Donor Registry
• HLA and Disease Resources :

    HLA-B27 and Spondyloarthropathy

Select Entries from OMIM

    Mechanisms of HLA Association in Disease from the Institute of Transplantation Immunology [Norway]

    Rheumatic Diseases A nice lecture outline from Temple University

    Major Histocompatibility Complex and Rheumatoid Arthritis

A Cutting Edge Article for RHEUMA21ST by Editor Robert F. Willken

• IMGT/HLA Database - The IMGT/HLA Database is part of the international ImMunoGeneTics IMGT project and provides a specialist sequence databases for sequences of the human major histocompatibility complex (HLA). This includes all official sequences for the WHO HLA Nomenclature Committee For Factors of the HLA System. Development of this database has been undertaken by James Robinson, Julia G Bodmer and Steven GE Marsh. [UK]
• Immunogenomic Data-Analysis Working Group (IDAWG)
• Online Mendelian Inheritance in Man (OMIM) - This database is a catalog of human genes and genetic disorders authored and edited by Drs. Moyra Smith, Victor A. McKusick and their colleagues at Johns Hopkins and elsewhere, and developed for the World Wide Web by NCBI, the National Center for Biotechnology Information. The database contains textual information, pictures, and reference information. It also contains copious links to NCBI's Entrez database of MEDLINE articles and sequence information. The following are direct links to MHC entries:
  • HLA-A
  • HLA-B
  • HLA-C
  • HLA-DMA
  • HLA-DMB
  • HLA-DNA
  • HLA-DOB
  • HLA-DPA1
  • HLA-DPB1
  • HLA-DQA1
  • HLA-DQB1
  • HLA-DR
  • HLA-E
  • HLA-G
  • HLA-H

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Molecular Biology and Genetics

databases, protocols and other resources for molecular genetics

• Association for Molecular Pathology Homepage - source for info on clinical application of molecular biology techniques with links to related sites.
• ATCC - The American Type Culture Collection - search this catalog to find available cell lines.
• The Comprehensive Protocol Collection (CPC) from Dartmouth U.
• Genome Database-Home Page
• The ImMunoGeneTics Database ,IMGT, is an integrated specialised database containing nucleotide sequence information of genes important in the function of the immune system, including the B cell antigen receptor (Immunoglobulin or Ig), the T cell antigen receptor (TcR) and the class I and class II genes of the Major Histocompatibility Complex (MHC). [FR]
• National Center for Genome Resources
• PCRLinks - a website that provides selected Internet resources about the Polymerase Chain Reaction Technique.
• Search GenBank
• Sequence Submission Forms and Data Retrieval

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Press Policies

The American Society for Histocompatibility and Immunogenetics (ASHI) welcomes press coverage of its major meetings, specialty conferences, and regional educational workshops. Representatives from recognized news organizations or publications are cordially invited to attend scientific sessions at these events for the express purpose of gathering news and information to produce editorial coverage of the meetings.

In addition to the Annual Meeting, ASHI holds a series of educational workshops and specialty meetings throughout the year. The following policies and guidelines have been prepared for news media interested in covering these meetings. If you have any questions regarding policies or available resources, please contact ASHI’s communications manager at . We look forward to working with you.

Complimentary registration is available to representatives of print, electronic and Internet general interest media and healthcare trade media (collectively known as press). To register as press, journalists must contact ASHI’s communications manager at least two weeks in advance of the meeting. There will be no on-site media registration available.

Journalists may attend the conference and report about research presented at the meeting, only if they have prior approval from the scientists presenting the research. Registration for the Annual Meeting, educational workshops or special conferences will be coordinated through ASHI’s communications manager.

To qualify as press, journalists must present media identification or a business card issued by a recognized news organization in addition to two bylined medical articles. Freelance journalists must also present a letter of assignment on letterhead from a recognized news organization or publication.

Journalists working for medical publishing companies must have appropriate press credentials (i.e., proof of an editorial assignment) in order to register and the publication must meet the following criteria:

- Must have multiple sponsors (no single-sponsor publications)
- Must have complete editorial freedom from their sponsors
- Exhibitors will not be allowed to register as press unless they can provide proof of an editorial assignment

Journalists reporting for online media outlets who wish to register as press must work for news-making organizations that meet the following criteria:

- The Web site must provide original, editorial news coverage
- Editorial content must be independent of advertising and sponsorship
- Advertising on the Web site must be clearly identifiable as such
- Any sponsors of the Web site should be clearly identified as such and should be multiple in number (i.e., no single-sponsored Web sites)

No filming or photography is allowed during any of the program sessions, including general sessions, symposia, workshops, and oral or poster presentations.

All news releases regarding presentations made at the specialty conferences must indicate that they are embargoed for release at the date and time the data are presented at the meeting.

Reporters, producers and editors agree to the embargoes and release times stated on the news releases and other materials. Failure to abide by the embargoes will result in suspension of credentials, which will affect attendance at the current and future conferences and ability to receive advance press materials.

Information regarding media registrants is proprietary. ASHI does not make available press registration lists.

Media events or news briefings other than those organized by ASHI are not permitted in any ASHI meeting areas without prior consent from ASHI’s communications manager.

ASHI reserves the right to bar from this and future meetings any journalist who deliberately promotes the viewpoint of one company or institution, or who attempts to solicit manuscripts, advertising, or subscriptions from registrants or exhibitors.

For more information regarding ASHI specialty conferences please contact:

Communications Manager
American Society for Histocompatibility and Immunogenetics
15000 Commerce Pkwy., Suite C
Mt. Laurel, NJ 08054
Telephone: 856-642-4420
Email:

*Please note that smoking is not permitted in meeting areas or at other ASHI events.

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Related Meetings

2012 Meeting Dates

16th International HLA and Immunogenetics Workshop and Conference

For more information: http://www.16ihiw.org

Joint IHWS/EFI/BSHI Conference

May 28 - June 3, 2012 Liverpool

For more information: http://ihiwefibshi.org/

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FOCIS 2012

June 20 - June 23, 2012
Vancouver, BC, Canada

For more information: http://www.focisnet.org/FOCIS/index.php?option=com_content&task=view&id=138&Itemid=9

 

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American Foundation for Donation & Transplantation (AFDT) 

16th Histocompatibility Specialist Course
June 22-30, 2012
New York, New York Hotel & Casino in Las Vegas, NV
http://www.amfdt.org

The curriculum is designed for senior technologists and new laboratory directors involved in the day to day management and development of the
histocompatibility laboratory. Applicants should have a background in immunology, Immunogenetics and histocompatibility.
Cost: $1,500
Hotel per weeknight: $69++; weekend: $99++
Registration to start January 2012

For more information: Contact: Arlene Skinner, 800-kidney9,

 

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ARB

Accreditation Review Board

Accreditation Review Board (ARB) meetings are closed meetings, open only to the Accreditation Review Board.

2010 -2011 Meetings

December 3 - 5, 2010, Las Vegas, Nevada

April 1 - 3, 2011, Portland, Oregoen

July 28 - 30, 2011, Atlanta, Georgia

December 2011 TBD

If you are on the ARB and have a question regarding the above meetings, please contact Nadege Toth, the Associate Meeting Manager at 856.793.0766 or via email to .

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Membership Directory

The ASHI Membership Directory is a copyrighted document that is not for commercial use.  It may be used for personal or professional use. It is available in two formats. A listing of Accredited Laboratories may be found in the Accreditation section of the Lab Center.

PDF  MEMBERSHIP DIRECTORY (for downloading)
The PDF version of the directory is published annually and is available to ASHI members upon request.  For the most up-to-date information, please use the searchable online directory provided below. Request can be made by emailing .

SEARCHABLE ONLINE DIRECTORY (online search)

For the most up-to-date directory information, please use the search box listed below.

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White Papers

• Pre-Transplant Assessment of Donor-Reactive, HLA-Specific Antibodies in Renal Transplantation: Contraindication vs Risk (pdf, 107KB)