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Standards for Histocompatibility Testing
(4/98) Copyright © 1995 - 2002 American Society for Histocompatibility and Immunogenetics. All rights reserved.

Section L - Platelet and Granulocyte Transfusion

L1.000 HLA typing.

L1.100 The patient and members of his immediate family should be typed for HLA-A and B antigens.

L1.200 Typing for HLA-C,D,DR, DQ and DP is not necessary.

L2.000 The donor should give his informed consent before blood is taken for typing and before the donor is placed on a list of donors available to be called.

L2.100 Donor records should be maintained so that donors can be rapidly retrieved according to HLA type.

L3.000 Screening the sera of patients for lymphocytotoxic antibodies at intervals is an appropriate way to detect alloimmunization.

L4.000 Crossmatching.

L4.100 Lymphocytotoxic crossmatches are optional.

L4.200 Crossmatching by techniques which utilize donor platelets or granulocytes as the target cells is preferred.

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Minimal criteria which all accredited histocompatibility laboratories must meet

A - General Policies
B - Personnel Qualifications
C - General Comments and Quality Assurance
D - HLA Antigens
E - Serologic Typing - HLA Class I
F - Serologic Typing - HLA Class II
G - Mixed Leukocyte Culture Tests
H - Antibody Screening
I - Renal Transplantation
J - Non-Renal Transplantation
K - Marrow Transplantation
L - Plat & Gran Transfusion
M - Disease Association
N - Parentage Testing
P - Nucleic Acid Analysis
Q - Flow Cytometry
R - ELISA


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